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Categories: Chronic Illness, Relationships
Published Identifying a new liver defender: The role of resident macrophages (via sciencedaily.com) Original source
Researchers discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier conditions. Identified as 'sentinel macrophages,' they are activated by isoallo-lithocholic acid. This finding holds promise for developing preventive and therapeutic strategies for liver chronic inflammatory diseases, such as metabolic dysfunction-associated steatohepatitis (MASH), by enhancing the function of these macrophages to mitigate inflammation and improve treatment efficacy.
Published Physical activity in nature helps prevent several diseases, including depression and type 2 diabetes (via sciencedaily.com) Original source
Physical activity in natural environments prevent almost 13,000 cases of non-communicable diseases a year in England and save treatment costs of more than 100 million, new research has found.
Published Genetic variations may predispose people to Parkinson's disease following long-term pesticide exposure, study finds (via sciencedaily.com) Original source
A new study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.
Published Solving the riddle of the sphingolipids in coronary artery disease (via sciencedaily.com) Original source
Investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.
Published Low intensity exercise linked to reduced depression (via sciencedaily.com) Original source
New research has found a significant association between participating in low to moderate intensity exercise and reduced rates of depression.
Published Don't be a stranger -- study finds rekindling old friendships as scary as making new ones (via sciencedaily.com) Original source
Psychologists have found that people are as hesitant to reach out to an old friend as they are to strike up a conversation with a stranger, even when they had the capacity and desire to do so.
Published Liver cancer: Molecular signaling pathway of tumor development decoded (via sciencedaily.com) Original source
As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths. While the treatment options for this aggressive type of cancer remain limited, the incidence is increasing. A research team has now described a molecular signalling pathway that plays a key role in the development of liver cancer, thereby identifying a potential new starting point for the development of therapeutic treatments.
Published Exploring brain synchronization patterns during social interactions (via sciencedaily.com) Original source
Social interactions synchronize brain activity within individuals and between individuals. In a new study, researchers compared brain synchronization between pairs of people with relatively strong social ties (acquaintance pairs) and pairs with almost no social ties (stranger pairs). The study found that during a cooperative task, the stranger pairs exhibited more closely connected brain networks compared to the acquaintance pairs. These findings challenge the conventional understanding that stronger social bonds lead to greater brain synchronization.
Published Follow-up 50 years on finds landmark steroid study remains safe (via sciencedaily.com) Original source
A follow-up analysis 50 years later finds no adverse heart health risk from Professor Mont Liggins' landmark steroid study to reduce illness and death for pre-term babies.
Published Study finds COVID-19 pandemic led to some, but not many, developmental milestone delays in infants and young children (via sciencedaily.com) Original source
Infants and children 5 years old and younger experienced only 'modest' delays in developmental milestones due to the COVID-19 pandemic disruptions and restrictions, a study finds.
Published Analyzing the progression in retinal thickness could predict cognitive progression in Parkinson's patients (via sciencedaily.com) Original source
Although there are still some aspects pending confirmation for its use in the clinical setting, and its resolution needs to be improved slightly, a study has shown that a method routinely used to carry out ophthalmological tests can also be used to monitor the neurodegeneration that occurs in Parkinson's patients. In the course of the research it was found that the neurodegeneration of the retina probably precedes cognitive impairment.
Published Coal train pollution increases health risks and disparities (via sciencedaily.com) Original source
The first health impact study of coal train pollution centers on the San Francisco Bay Area, with scientists finding communities near passing coal trains suffer worse health outcomes.
Published Potential new treatment path for lasting Lyme disease symptoms (via sciencedaily.com) Original source
Researchers have identified a potential new treatment for persistent neurological symptoms of Lyme disease, commonly seen even after antibiotic use. The study found that fibroblast growth factor receptor inhibitors, previously studied in cancer, significantly reduced inflammation and cell death in infected brain and nerve tissues.
Published How data provided by fitness trackers and smartphones can help people with MS (via sciencedaily.com) Original source
Monitoring and treating a case of multiple sclerosis requires reliable and long-term data on how the disease is progressing in the person in question. Fitness trackers and smartphones can supply this data, as a research team has now shown.
Published Adults with congenital heart disease faced higher risk of abnormal heart rhythms (via sciencedaily.com) Original source
Adults with congenital heart defects were more likely to experience an abnormal, irregular heartbeat, finds a new study.
Published Common HIV treatments may aid Alzheimer's disease patients (via sciencedaily.com) Original source
Scientists have identified promising real-world links between common HIV drugs and a reduced incidence of Alzheimer's disease.
Published Scientists identify cell vulnerability 'fingerprint' related to Parkinson's, Lewy body dementia (via sciencedaily.com) Original source
A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias. The findings reveal that brain cells with Lewy bodies exhibit a specific gene expression pattern akin to a disease-related fingerprint.
Published Family and media pressure to lose weight in adolescence linked to how people value themselves almost two decades later (via sciencedaily.com) Original source
People who as teenagers felt pressure to lose weight from family or from the media, females, people who are not heterosexual, and people experiencing socioeconomic disadvantage, are most at risk of 'internalized' weight stigma, new research has found.
Published Microplastics make their way from the gut to other organs (via sciencedaily.com) Original source
Researchers have found that microplastics -- are having a significant impact on our digestive pathways, making their way from the gut and into the tissues of the kidney, liver and brain.
Published Physical activity reduces stress-related brain activity to lower cardiovascular disease risk (via sciencedaily.com) Original source
Over a ten-year period, biobank participants who met recommended levels of physical activity had a 23% lower risk of cardiovascular disease, and the protective effects were even more pronounced in individuals with depression.