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Categories: Mental Health Research

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Using artificial intelligence (AI) to analyze specialized brain MRI scans of adolescents with and without attention-deficit/hyperactivity disorder (ADHD), researchers found significant differences in nine brain white matter tracts in individuals with ADHD.

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A novel pilot study incorporating mindfulness into exposure therapy shows promise for reducing symptoms of post-traumatic stress in cardiac arrest survivors. One in three survivors of cardiac arrest survivors develop PTSD,  increasing their risk of mortality, yet no specific treatment has been developed for this population.  

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Taking into account whether people believe they are receiving a real treatment or a fake one (placebo) could provide better insights that could help improve interventions for conditions such as depression and ADHD. 

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Experiences of discrimination and acculturation are known to have a detrimental effect on a person's health. For pregnant women, these painful experiences can also affect the brain circuitry of their children, a new study finds. These effects, the researchers say, are separate from those caused by general stress and depression. The study was published in the journal Neuropsychopharmacology.

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Depression is one of the most common mental illnesses in the world, but current anti-depressants have yet to meet the needs of many patients. Neuroscientists recently discovered a small molecule that can effectively alleviate stress-induced depressive symptoms in mice by preventing aversive memory formation with a lower dosage, offering a new direction for developing anti-depressants in the future.

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Children whose mothers are highly stressed, anxious or depressed during pregnancy may be at higher risk for mental health and behavior issues during their childhood and teen years, according to new research.

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Researchers have shed new light on why electroconvulsive therapy has such a high success rate, a mystery that has puzzled doctors and scientists for almost a century. Findings could help improve this controversial treatment.

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We've known for more than a century that women outlive men. But new research shows that, at least in the United States, the gap has been widening for more than a decade.

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A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according to new research. The study shows that in B.C. alone, implementing pharmacogenomic testing could save the provincial public health system an estimated $956 million over 20 years.

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New research shows promise in treating addiction cravings by combining eye movements and guided instructions to process memories. Researchers transformed dysfunctional memories stored in the brain through processing and integration. EMDR was as effective as cognitive behavioral therapy for cravings with the combination of both resulting in more reduction in craving than cognitive behavioral therapy (CBT) alone. Both groups (experimental group and control group using only CBT) had clinically significant reductions in cravings, repetitive negative thoughts, and irrational cognitions, with the experimental group showing greater decreases overall.  

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A surprising thing happened when researchers began exploring whether early-life stress compounds the effects of a childhood head injury on health and behavior later in life: In an animal study, stress changed the activation level of many more genes in the brain than were changed by a bump to the head.

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Research and treatment of psychiatric disorders are stymied by a lack of biomarkers -- objective biological or physiological markers that can help diagnose, track, predict, and treat diseases. In a new study, researchers use a very large dataset to identify predictive brain imaging-based biomarkers of mental illness in adolescents.

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A new study has found that individuals with severe mental illness are almost twice as likely to report physical multimorbidity, emphasizing the critical importance of addressing the intersection between mental and physical health.

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Researchers have identified a new neural circuit in the brain which produces a strong sense of discomfort when activated. The discovery also allows them to show for the first time that the subthalamic nucleus, a structure in the brain that controls voluntary movements, may also play a role in the development of depression. The results could lead to better treatments for Parkinson's disease.

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A new study has found postpartum individuals living in states with generous mandated paid family and medical leave (PFML) are more likely to breastfeed and less likely to experience postpartum depression symptoms compared to those living in states with little or no mandated state-paid leave. The findings were even more pronounced among lower-income populations covered by Medicaid.

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Major depressive disorder (MDD) is a widespread mental health condition that for many is disabling. It has long been appreciated that MDD has genetic as well as environmental influences. In a new study researchers identify a gene that interacted with stress to mediate aspects of treatment-resistant MDD in an animal model.

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A new study has shown that women who are taking the oral contraceptive pill are less likely to report depression. The research, which analysed data from 6,239 women in the United States aged 18-55 years old, found that the prevalence of major depression amongst users of the oral contraceptive pill (OCP) was significantly lower, at 4.6%, compared to former OCP users (11.4%).

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A research team has identified the most widespread genetic contribution by Denisovans to date. The study reveals that the genetic variant observed, which affects zinc regulation, could have signified an evolutionary advantage in our ancestors' adaptation to the cold. The study also reveals that this genetic adaptation may have predisposed modern humans to neuropsychiatric disorders.

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Youngest children in their class with ADHD are just as likely to keep the diagnosis when enter adulthood as older pupils in their year group. In the past, scientists have questioned the validity of ADHD in younger pupils, arguing they are only diagnosed because they are less mature than their peers. But this study shows that these children are no more likely to lose ADHD diagnosis over time than those born towards the start of the school year.

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In a study of different types of distraction involving more than 1,000 participants, researchers statistically derived a novel measure -- dubbed the 'd factor' -- that could represent a person's general tendency towards distraction and may be linked with attention-deficit/hyperactivity disorder (ADHD).