Showing 20 articles starting at article 1
Categories: Diabetes
Published Researchers identify causal genetic variant linked to common childhood obesity
(via sciencedaily.com) Original source Researchers have identified a causal genetic variant strongly associated with childhood obesity. The study provides new insight into the importance of the hypothalamus of the brain and its role in common childhood obesity and the target gene may serve as a druggable target for future therapeutic interventions.
Published An electrifying discovery may help doctors deliver more effective gene therapies
(via sciencedaily.com) Original source In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering has developed a stimulating method that could make the human body more receptive to certain gene therapies.
Published Cranberry extracts could boost microbiota and counter cardiometabolic diseases
(via sciencedaily.com) Original source Cranberry extracts appear to improve intestinal microbiota and help prevent chronic diseases such as diabetes and cardiovascular diseases. The study reported beneficial effects after only four days of use.
Published Experimental type 1 diabetes drug shelters pancreas cells from immune system attack
(via sciencedaily.com) Original source Scientists say that an experimental monoclonal antibody drug called mAb43 appears to prevent and reverse the onset of clinical type 1 diabetes in mice, and in some cases, to lengthen the animals' lifespan.
Published Food in sight? The liver is ready!
(via sciencedaily.com) Original source What happens in the body when we are hungry and see and smell food? A team of researchers has now been able to show in mice that adaptations in the liver mitochondria take place after only a few minutes. Stimulated by the activation of a group of nerve cells in the brain, the mitochondria of the liver cells change and prepare the liver for the adaptation of the sugar metabolism. The findings could open up new avenues for the treatment of type 2 diabetes.
Published Physical activity in nature helps prevent several diseases, including depression and type 2 diabetes
(via sciencedaily.com) Original source Physical activity in natural environments prevent almost 13,000 cases of non-communicable diseases a year in England and save treatment costs of more than 100 million, new research has found.
Published Genetics predict type 2 diabetes risk and disparities in childhood cancer survivors
(via sciencedaily.com) Original source Learn how ancestry changes genetic risk variants' impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk. Learn how ancestry changes genetic risk variants' impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk.
Published Follow-up 50 years on finds landmark steroid study remains safe
(via sciencedaily.com) Original source A follow-up analysis 50 years later finds no adverse heart health risk from Professor Mont Liggins' landmark steroid study to reduce illness and death for pre-term babies.
Published Shoe technology reduces risk of diabetic foot ulcers
(via sciencedaily.com) Original source Researchers have developed a new shoe insole technology that helps reduce the risk of diabetic foot ulcers, a dangerous open sore that can lead to hospitalization and leg, foot or toe amputations.
Published Siblings with unique genetic change help scientists progress drug search for type 1 diabetes
(via sciencedaily.com) Original source Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress the search for new treatments in type 1 diabetes.
Published New study focuses on the placenta for clues to the development of gestational diabetes
(via sciencedaily.com) Original source A new study has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.
Published Take it from the rats: A junk food diet can cause long-term damage to adolescent brains
(via sciencedaily.com) Original source A study on the effects of a junk food diet on rats reinforces scientific understanding about the gut-brain connection.
Published Scientists uncover a missing link between poor diet and higher cancer risk
(via sciencedaily.com) Original source A research team has unearthed new findings which may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from poor diet. The insights gained from this study hold promise for advancing cancer prevention strategies aimed at promoting healthy aging.
Published This outdated diabetes drug still has something to offer
(via sciencedaily.com) Original source Researchers have discovered the biochemical workings of an old-fashioned diabetes drug, and it's helping them develop new, safer alternatives.
Published Does the time of day you move your body make a difference to your health?
(via sciencedaily.com) Original source Undertaking the majority of daily physical activity in the evening is linked to the greatest health benefits for people living with obesity, according to researchers who followed the trajectory of 30,000 people over almost 8 years.
Published Global research team finds no clear link between maternal diabetes during pregnancy and ADHD in children
(via sciencedaily.com) Original source An international research team has just provided valuable evidence through a 20-year longitudinal study to address the longstanding debate concerning the potential impact of maternal diabetes on attention-deficit/hyperactivity disorder (ADHD) in children. This study, analysing real-world data from over 3.6 million mother-baby pairs in China's Hong Kong, Taiwan, New Zealand, Finland, Iceland, Norway and Sweden, showed that maternal diabetes during pregnancy is unlikely to be a direct cause of ADHD.
Published Beating back bitter taste in medicine
(via sciencedaily.com) Original source The bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are particularly sensitive to bitter taste. A team found that the diabetes drug rosiglitazone could partially block the bitter taste of some especially bad-tasting medications. The hope is that repurposed drugs could be added in small doses to other medicines to make them less bitter and taste better, thereby encouraging compliance with bitter drug regimens.
Published Few newly diagnosed type 2 diabetics succeed in losing weight -- weight gain linked to much higher risk of complications
(via sciencedaily.com) Original source A register-based study identified three distinct BMI trajectory groups among patients with newly diagnosed type 2 diabetes. In a four-year follow-up, most patients followed a stable trajectory without much weight change. Only 10% of patients lost weight, whereas 3% gained weight. Mean BMI exceeded the threshold of obesity in all groups at baseline. Weight loss is a central treatment goal in type 2 diabetes, but the study shows that few patients succeed in it.
Published Study finds less invasive, safer option for removing benign pancreatic tumors
(via sciencedaily.com) Original source Researchers describe a new technique for the minimally invasive removal of benign tumors located in the challenging posterior head of the pancreas (right side of abdomen, nestled in the curve of the duodenum (or first part of the small intestine). The technique, called the retro-laparoscopic approach, allows surgeons to safely and effectively remove these tumors without removing healthy pancreatic tissue, thereby preserving organ functionality.
Published Large language models respond differently based on user's motivation
(via sciencedaily.com) Original source A new study reveals how large language models (LLMs) respond to different motivational states. In their evaluation of three LLM-based generative conversational agents (GAs)--ChatGPT, Google Bard, and Llama 2, scientists found that while GAs are able to identify users' motivation states and provide relevant information when individuals have established goals, they are less likely to provide guidance when the users are hesitant or ambivalent about changing their behavior.