Published Research challenges current thinking on the genetic causes of very early menopause



The genetic causes of very early menopause will have to be reconsidered after researchers found that nearly all women who carried variations thought to cause the condition in fact had their menopause at an older age.
Published One in five women become pregnant naturally after having a baby conceived with IVF



New research analyzed data from 11 studies of over 5,000 women around the world between 1980 and 2021, to evaluate how common it is to get pregnant naturally after having a baby conceived by fertility treatment. Around 20% of women who needed fertility treatment, such as IVF, to conceive their first child are likely to get pregnant naturally in the future, finds a new study.
Published Hidden mechanism connects cancer and diabetes



Insulin resistance is usually associated with type 2 diabetes. Now researchers have found it in cancer patients and learned that it can cause cancer to spread faster.
Published Fewer meals may prevent Type 2 diabetes, obesity



When intermittent fasting became all the rage among Hollywood celebrities, skeptics balked at the idea of skipping meals. But new research suggests the celebs might not have been that far off. The review found that a specific type of restricted eating may reduce the chances of developing Type 2 diabetes and improve your overall health. Known as time-restricted eating, this type of fasting means having regular but fewer meals, cutting out late-night snacks and not eating for 12 to 14 hours (often overnight).
Published Machine-learning method used for self-driving cars could improve lives of type-1 diabetes patients



The same type of machine learning methods used to pilot self-driving cars and beat top chess players could help type-1 diabetes sufferers keep their blood glucose levels in a safe range.
Published New diagnostic finds intact sperm in infertile men



Researchers develop new diagnostic tool to visualize protein biomarkers of well-developed sperm to determine if surgical sperm extraction may be successful for certain infertile men.
Published Elimination of type of bacteria suggests treatment for endometriosis



A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.
Published Sea cucumbers: The marine delicacy that can deter diabetes



They're a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research.
Published Can exercise help counteract genetic risk of disease?



Staying active could help keep the onset of type 2 diabetes at bay, even if someone has a genetic risk of developing the disease. Researchers say this highlights the importance of exercise in chronic disease prevention.
Published Scientists target human stomach cells for diabetes therapy



Stem cells from the human stomach can be converted into cells that secrete insulin in response to rising blood sugar levels, offering a promising approach to treating diabetes, according to a preclinical study.
Published Experimental drug inhibits or prevents diabetic eye disease



Researchers say they have evidence that an experimental drug may prevent or slow vision loss in people with diabetes. The results are from a study that used mouse as well as human retinal organoids and eye cell lines.
Published Researchers successfully induce primate oocytes in the lab



The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.
Published Afternoon exercise linked with greater improvements in blood sugar levels for patients with type 2 diabetes



A new study uses data from the Look AHEAD (Action for Health in Diabetes) study, a randomized controlled trial that compared an intensive lifestyle intervention with diabetes support and education in patients diagnosed with type 2 diabetes and overweight or obesity to track the development of cardiovascular disease over time.
Published Researchers map the brain during blood sugar changes



Researchers have successfully mapped specific regions in the brain that are activated in association with changes in blood sugar -- also known as glucose -- providing fundamental location information that could ultimately lead to more targeted therapies for people who struggle with conditions like diabetes.
Published Artificial pancreas reduces disease management burden for people with diabetes



Researchers design a novel algorithm for controlling implanted insulin pumps that accounts for the unique characteristics of individual patients. Their model, tested using an FDA-approved diabetes computer simulation, proves intraperitoneal (within the abdominal cavity) insulin delivery is fast and closely mimics natural physiological insulin delivery. They developed a model that can account for individual patient differences and validated a pump control algorithm that does not require meal announcement.
Published Happy worms have healthy eggs



Researchers have exposed roundworms (a well-established model organism in biological research) to selective serotonin reuptake inhibitors (SSRIs), a class of drugs used for treating depression and anxiety. Surprisingly, this treatment improved the quality of aging females' egg cells.
Published Scientists discover the dynamics of an 'extra' chromosome in fruit flies



Most chromosomes have been around for millions of years. Now, researchers have revealed the dynamics of a new, very young chromosome in fruit flies that is similar to chromosomes that arise in humans and is associated with treatment-resistant cancer and infertility. The findings may one day lead to developing more targeted therapies for treating these conditions.
Published High-throughput experiments might ensure a better diagnosis of hereditary diseases



All human beings are genetically very similar, sharing approx. 99.9% of the DNA code. The remaining 0.1% explains the natural differences between people, including our predisposition to hereditary diseases. Although sequencing of our genetic material is becoming a routine diagnostic analysis, it is unfortunately far from simple to determine whether specific small differences in our DNA affect our risk of developing disease. The usefulness of DNA sequencing is therefore often limited to the few cases where it is already known if a gene variant increases the risk of disease.
Published Potential breakthrough in Type 1 diabetes treatment



Scientists identified three biomaterial formulations that could help develop a more sustainable, long-term, self-regulating way to treat Type 1 diabetes using a new screening technique that involves tagging each biomaterial formulation in a library of hundreds with a unique 'barcode.'
Published Arterial stiffness may cause metabolic syndrome in adolescents via an increase in fasting insulin and LDL cholesterol



Arterial stiffness may be a novel risk factor for metabolic syndrome in teens.