Showing 20 articles starting at article 1
Categories: Gynecology
Published Provides new explanation for why placenta may not properly separate at birth, putting mother and newborn at risk
(via sciencedaily.com) Original source A new study may change the way clinicians and scientists understand, diagnose and treat placenta accreta spectrum disorder, a serious condition in which the placenta fails to separate from the uterus at birth, jeopardizing the life and health of both mother and baby.
Published Candida evolution disclosed: New insights into fungal infections
(via sciencedaily.com) Original source Identification of genes under recent selection provides insights into the molecular mechanisms of human-related adaptation in Candida pathogens. The study reveals both known and novel genetic variants associated with drug resistance, offering potential targets for improved antifungal therapies.
Published How do painful fibroids grow?
(via sciencedaily.com) Original source Insights into how uterine tumors grow could give hope to millions of women who deal with painful fibroids.
Published Having a C-section is related to difficulties with conceiving
(via sciencedaily.com) Original source Women who delivered their previous pregnancy by C-section spent a longer time trying to conceive their next pregnancy. Additionally, women who spent a longer time trying to conceive their current pregnancy were more likely to deliver by C-section. The authors concluded that differences in time spent trying to conceive are unlikely to be due to the surgical procedure itself.
Published Blood clotting risk quickly drops after stopping hormonal contraceptives
(via sciencedaily.com) Original source Using birth control pills and other hormone-based contraceptives is known to elevate the risk of blood clots, but a new study suggests that this risk largely goes away within two to four weeks after one stops using these contraceptives. The findings can help patients and doctors weigh the benefits and risks of hormonal contraceptives and guide when to stop using them ahead of events that could further increase the risk of dangerous clots, such as major surgery, prolonged periods of immobility, or when tapering anticoagulant medications after a blood clot.
Published Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence
(via sciencedaily.com) Original source Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.
Published Fungal infection in the brain produces changes like those seen in Alzheimer's disease
(via sciencedaily.com) Original source Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.
Published Brain is 'rewired' during pregnancy to prepare for motherhood
(via sciencedaily.com) Original source Researchers have shown that pregnancy hormones ‘rewire’ the brain to prepare mice for motherhood. The findings show that both estrogen and progesterone act on a small population of neurons in the brain to switch on parental behavior even before offspring arrive. These adaptations resulted in stronger and more selective responses to pups.
Published New device rapidly controls postpartum hemorrhage
(via sciencedaily.com) Original source A study led by obstetricians has shown that a new device can rapidly control postpartum hemorrhage, a major cause of severe maternal morbidity and death, in a wide range of patients.
Published Natural compound found in plants inhibits deadly fungi
(via sciencedaily.com) Original source A new study finds that a natural compound found in many plants inhibits the growth of drug-resistant Candida fungi -- including its most virulent species, Candida auris, an emerging global health threat.
Published A gut hormone for controlling appetite doubles as an immune regulator for the fungal microbiome
(via sciencedaily.com) Original source Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research.
Published Deadly fungus beaten with new type of treatment
(via sciencedaily.com) Original source Researchers have discovered a new way to attack fungal infections. The key is to block fungi from being able to make fatty acids, the major component of fats. Resistance to anti-fungal drugs is increasing and this new approach will be particularly useful because it works in a new way and affects a broad range of fungal species.
Published New study using human fibroid cells supports use of green tea compound as treatment for uterine fibroids
(via sciencedaily.com) Original source In a pre-clinical, proof-of-concept study, researchers found that epigallocatechin gallate (EGCG), a green tea compound with powerful antioxidant properties, could be promising for both treating and preventing uterine fibroids. Results of the study add to growing evidence that EGCG may reduce fibroid cell growth. The study was specifically designed to identify the biochemical mechanisms responsible for EGCG action in fibroid cells.
Published Elimination of type of bacteria suggests treatment for endometriosis
(via sciencedaily.com) Original source A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.
Published Dynamic expression of brain serotonin receptors across the menstrual cycle provides clues about premenstrual dysphoric disorder
(via sciencedaily.com) Original source A new study explores the interplay between the serotonin system and estradiol in the brain, showing that the central nervous system in patients with premenstrual dysphoric disorder (PMDD) seems to increase serotonin transporter density from the periovulatory phase (when estradiol levels are high) to premenstrual cycle phase (when both estradiol and progesterone are decreasing). The findings have the potential to advance the clinical treatment of PMDD.
Published Migraines during menstruation: Low estrogen levels paired with higher CGRP levels may jump start migraine
(via sciencedaily.com) Original source As estrogen levels fluctuate, a new study has found for female participants with migraine, their levels of the protein calcitonin gene-related peptide (CGRP) that plays a key role in starting the migraine process also fluctuate.
Published Does lifetime exposure to estrogen affect risk of stroke?
(via sciencedaily.com) People with a higher cumulative estrogen exposure throughout their life may have a lower risk of stroke, according to a new study. The lower risk was found for both ischemic stroke and intracerebral hemorrhage.
Published Birth choices after previous cesarean and risk of pelvic floor surgery
(via sciencedaily.com) Original source Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who have had a previous cesarean section when planning how to give birth in their next pregnancy.
Published Fungal association with tumors may predict worse outcomes
(via sciencedaily.com) The presence of some fungal species in tumors predicts -- and may even help drive -- worse cancer outcomes, according to a new study.
Published Advanced imaging sheds light on immune escape of shape-shifting fungus
(via sciencedaily.com) Original source Fungal pathogens have a major global impact upon human health -- they are often difficult to diagnose and treat, and there is an urgent need for better diagnostics and more effective antifungal treatments. Using newly developed imaging technologies, researchers have now revealed how Candida albicans, a common fungus, evades immune responses. According to the researchers this involves an 'alien-like' shape shifting that allows the fungus to break out of immune cells.