Showing 20 articles starting at article 1
Categories: Birth Defects, Eating Disorders
Published Research sheds light on how proteins linked to Alzheimer's disease influence neuronal growth
(via sciencedaily.com) Original source New research has shed light in the complex interplay between cell proteins, and how they impact on neurons in neurodevelopmental disorders and Alzheimer's disease.
Published Study explores role of epigenetics, environment in differing Alzheimer's risk between Black and white communities
(via sciencedaily.com) Original source Environmentally caused alterations to specific areas of the genome -- known as imprint control regions -- during early development may contribute to the risk of developing Alzheimer's disease, and Black people may be more affected than white people.
Published Metabolism of autism reveals developmental origins
(via sciencedaily.com) Original source Researchers have shed new light on the changes in metabolism that occur between birth and the presentation of autism spectrum disorder (ASD) later in childhood. The researchers discovered that a small number of biochemical pathways are responsible for the majority of these changes, which could help inform new early detection and prevention strategies for autism.
Published Brain mechanisms underlying sensory hypersensitivity in a mouse model of autism spectrum disorder
(via sciencedaily.com) Original source A research team has identified the primary cause of sensory hypersensitivity in a mouse model of autism spectrum disorders (ASD).
Published Gene linked to learning difficulties has direct impact on learning and memory
(via sciencedaily.com) Original source A gene previously linked to intellectual disability has been found to regulate learning and memory in mice.
Published Genetics, not lack of oxygen, causes cerebral palsy in quarter of cases
(via sciencedaily.com) Original source The world's largest study of cerebral palsy (CP) genetics has discovered genetic defects are most likely responsible for more than a quarter of cases in Chinese children, rather than a lack of oxygen at birth as previously thought.
Published Pregnancy cytokine levels impact fetal brain development and offspring behavior
(via sciencedaily.com) Original source Researchers have discovered in a preclinical model that cytokines, proteins that control immune response, circulating in maternal blood during pregnancy may mitigate an offspring's risk for psychiatric conditions. The findings are surprising because circulating maternal cytokines are at such low levels that they were not implicated in fetal brain development and offspring behavior before.
Published Gene-based therapy restores cellular development and function in brain cells from people with Timothy syndrome
(via sciencedaily.com) Original source In a proof-of-concept study, researchers demonstrated the effectiveness of a potential new therapy for Timothy syndrome, an often life-threatening and rare genetic disorder that affects a wide range of bodily systems, leading to severe cardiac, neurological, and psychiatric symptoms as well as physical differences such as webbed fingers and toes.
Published Mosaics of predisposition cause skin disease
(via sciencedaily.com) Original source Clarifying the cause of a skin disease led to the discovery of a new disease-causing gene, a new category of diseases, and new perspectives for both counseling and therapy. The discovery is the first time that epigenetic silencing, the 'switching off' of an otherwise intact gene, has been recognized as the cause for a skin disease.
Published Genetic variant identified that shaped the human skull base
(via sciencedaily.com) Original source Researchers have identified a variant in the gene TBX1 as key in the development of the unique morphology at the base of the skull. TBX1 is present at higher levels in humans than in closely related hominins. Low TBX1 also occurs in certain genetic conditions causing altered skull base morphology. This study provides a greater understanding of human disease and evolution.
Published Adults with congenital heart disease faced higher risk of abnormal heart rhythms
(via sciencedaily.com) Original source Adults with congenital heart defects were more likely to experience an abnormal, irregular heartbeat, finds a new study.
Published Two key brain systems are central to psychosis
(via sciencedaily.com) Original source When the brain has trouble filtering incoming information and predicting what's likely to happen, psychosis can result, research shows.
Published Impact of aldehydes on DNA damage and aging
(via sciencedaily.com) Original source Researchers have discovered the connection between aldehydes, organic compounds produced by cells as part of metabolic processes, and rapid aging. Their findings indicate a potential treatment for diseases that lead to accelerated aging as well as a means to counteract aging in healthy people by controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.
Published Are lab-grown brain tissues ethical? There is no no-brainer answer
(via sciencedaily.com) Original source Researchers offer insights into the ethical dilemmas and legal complexities surrounding brain organoids, especially those derived from human fetal tissue. Their findings advocate for thorough regulatory frameworks to ensure that scientific and medical progress in this field is conducted responsibly and ethically, with strong regulations supported by sound ethical and legal principles.
Published Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases
(via sciencedaily.com) Original source Scientists report that a progressive neurodegenerative disease can be triggered by a viral infection. The mechanism relates to mitochondrial roles in antiviral defense mechanisms.
Published Even moderate alcohol usage during pregnancy linked to birth abnormalities
(via sciencedaily.com) Original source Researchers have found that even low to moderate alcohol use by pregnant patients may contribute to subtle changes in their babies' prenatal development, including lower birth length and a shorter duration of gestation.
Published YKT6 gene variants cause a new genetic disorder finds a new study
(via sciencedaily.com) Original source A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.
Published Synaptic protein change during development offers clues on evolution and disease
(via sciencedaily.com) Original source An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The findings offer first insights into the mechanism behind synaptic development and open up routes for research on possible treatments.
Published Study of different autism types finds shared mechanism that may respond to drugs
(via sciencedaily.com) Original source An analysis of how brains with different forms of autism develop has revealed common underlying mechanisms that may respond to existing medications.
Published Craving snacks after a meal? It might be food-seeking neurons, not an overactive appetite
(via sciencedaily.com) Original source Psychologists have discovered a circuit in the brain of mice that makes them crave food and seek it out, even when they are not hungry. When stimulated, this cluster of cells propels mice to forage vigorously and to prefer fatty and pleasurable foods like chocolate over healthier foods like carrots.