Showing 20 articles starting at article 1
Categories: Birth Defects, Chronic Illness
Published Neurodegeneration in myelin disease: No myelin is better than bad myelin
(via sciencedaily.com) Original source Efficient removal of abnormal myelin allows survival of nerve fibers targeted by adaptive immune cells, according to a novel study.
Published Repairing nerve cells after injury and in chronic disease
(via sciencedaily.com) Original source Researchers discovered a mechanism for repairing damaged nerves during peripheral neuropathy in mice, wherein the protein Mitf orchestrates nerve repair after both trauma-induced and chronic nerve damage conditions, like Charcot Marie Tooth disease. Their findings may inspire novel therapeutics that bolster repair function and heal peripheral neuropathy -- even in hereditary and developmental cases.
Published Spike in premature births caused by COVID, halted by vaccines, study finds
(via sciencedaily.com) Original source COVID-19 caused an alarming surge in premature births, but vaccines were key to returning the early birth rate to pre-pandemic levels, according to a new analysis of California birth records.
Published Early-stage stem cell therapy trial shows promise for treating progressive MS
(via sciencedaily.com) Original source An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage.
Published Researchers develop new method for prenatal genetic testing
(via sciencedaily.com) Original source Researchers have developed a non-invasive genetic test that can screen the blood of pregnant individuals to survey all genes from the fetal genome.
Published Anti-rheumatic drugs could prevent thyroid disease
(via sciencedaily.com) Original source Anti-rheumatic drugs used for rheumatoid arthritis might prevent the development of autoimmune thyroid disease, according to a new observational study.
Published Clinical trial results give new hope for children with rare gliomas
(via sciencedaily.com) Original source A collaboration of researchers has published successful results from a Phase II clinical trial for the treatment of BRAF mutated low-grade paediatric gliomas.
Published Coffee grounds may hold key to preventing neurodegenerative diseases
(via sciencedaily.com) Original source A team of researchers found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.
Published 1060 million people with 'other' musculoskeletal disorders by 2050
(via sciencedaily.com) Original source A category of musculoskeletal disorders of our joints, muscles, bones, ligaments, tendons and spine are on the rise and a new forecast is as many as 1060 million people -- up from 464 million -- will be living with related disabilities by 2050, placing even greater pressure on stretched healthcare systems.
Published More needs to be done to prevent dependence on pain medication
(via sciencedaily.com) Original source Dependence on pain medication is on the rise due to lack of vigilance by medical professionals, according to a new study. Patients dependent on pain medication describe feelings of 'living in a haze' and being ignored and misunderstood by the medical profession.
Published Nanoplastics promote conditions for Parkinson's across various lab models
(via sciencedaily.com) Original source Nanoplastics interact with a particular protein that is naturally found in the brain, creating changes linked to Parkinson's disease and some types of dementia.
Published Cheap medicines prevented migraine as well as expensive ones
(via sciencedaily.com) Original source A new study sheds light on what works best to prevent migraine attacks, and surprisingly, cheaper medicines worked as well as the expensive ones.
Published Comprehensive guideline on using biomarkers for monitoring Crohn's disease
(via sciencedaily.com) Original source New AGA guideline outlines reliable blood and stool tests to monitor inflammation that can reduce how often patients need invasive endoscopy.
Published Unravelling the secrets of neurodegenerative diseases, one protein at a time
(via sciencedaily.com) Original source Proteins misfolding and clumping together, a process known as aggregation, is a key feature seen in several neurological conditions, including Alzheimer's and Parkinson's diseases. These disorders involve the formation of small, potentially harmful structures called oligomers, which could serve as valuable indicators for early diagnosis. They are incredibly small, however, and much rarer than the healthy non-aggregated proteins. This makes it hard to detect and measure them accurately.
Published Lab-grown 'small blood vessels' point to potential treatment for major cause of stroke and vascular dementia
(via sciencedaily.com) Original source Scientists have grown small blood vessel-like models in the lab and used them to show how damage to the scaffolding that supports these vessels can cause them to leak, leading to conditions such as vascular dementia and stroke.
Published High levels of maternal stress during pregnancy linked to children's behavior problems
(via sciencedaily.com) Original source Children whose mothers are highly stressed, anxious or depressed during pregnancy may be at higher risk for mental health and behavior issues during their childhood and teen years, according to new research.
Published New therapeutic strategy to reduce neuronal death in amyotrophic lateral sclerosis
(via sciencedaily.com) Original source Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control. Scientists have now suggested a potential therapeutic strategy to tackle this pathology that has no treatment to date. It is a molecular trap that prevents one of the most common genetic ALS-causing peptide compounds, the Poly-GR dipeptide, from causing its toxic effects in the body. The results show that this strategy reduces the death of neurons in patients and in an animal model (vinegar flies) of the disease.
Published Exposure to air pollution in utero may affect reproductive system development
(via sciencedaily.com) Original source From invisible wafts of diesel exhaust to sun-choking plumes of orange smoke, air pollution is known to damage respiratory well-being. Now, research suggests another reason to hold our breath: Polluted air also may hurt reproductive health. In a study of air pollution data in relation to markers of reproductive development in infancy, Rutgers researchers found certain pollutants may negatively alter anogenital distance, a measure of prenatal exposure to hormones.
Published US men die 6 years before women, as life expectancy gap widens
(via sciencedaily.com) Original source We've known for more than a century that women outlive men. But new research shows that, at least in the United States, the gap has been widening for more than a decade.
Published Reducing systolic blood pressure to less than 120 mm Hg reduced cardiovascular event risk
(via sciencedaily.com) Original source An intensive three-year intervention to lower the top blood pressure number to less than 120 mm Hg was more effective at preventing death, heart attack, stroke and other cardiovascular events in adults at high risk for cardiovascular disease, compared to the standard treatment target of under 140 mm Hg, according to new research.