Showing 20 articles starting at article 1
Published Human embryo-like models created from stem cells to understand earliest stages of human development (via sciencedaily.com) Original source
Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why and how pregnancies fail.
Published What role does alternative splicing play in neurodegenerative disease? (via sciencedaily.com) Original source
Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these disorders.
Published Poorly insulated nerve cells promote Alzheimer's disease in old age (via sciencedaily.com) Original source
Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
Published Open-analysis platform for pediatric brain tumors provides robust data resource for childhood cancer research (via sciencedaily.com) Original source
Researchers have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, researchers have used this platform to identify initial findings about genetic variants associated with poorer outcomes that could help guide future diagnostic and therapeutic advances.
Published Scientists unveil RNA-guided mechanisms driving cell fate (via sciencedaily.com) Original source
The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.
Published Understanding the speed of brain communication (via sciencedaily.com) Original source
Called the human connectome, this structural system of neural pathways develops as people age. A new study shows transmission speed among brain regions increases into early adulthood. Learning more about neuron transmission may improve the understanding of psychological disorders.
Published A special omega-3 fatty acid lipid will change how we look at the developing and aging brain (via sciencedaily.com) Original source
Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.
Published Gene responsible for severe facial defects identified (via sciencedaily.com) Original source
Goldenhar syndrome is a rare congenital disease, affecting early fetal development. This syndrome includes malformations of varying severity, affecting different parts of the face. Its causes and modes of transmission are still poorly understood. An international collaboration has discovered that pathogenic variants of the FOXI3 gene -- responsible for the development of the ear -- cause one form of this developmental disorder. The scientists were also able to identify the modes of transmission of the disease when this particular gene is involved.
Published Problems with 'pruning' brain connections linked to adolescent mental health disorders (via sciencedaily.com) Original source
Problems with the brain's ability to 'prune' itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today. The findings may help explain why people are often affected by more than one mental health disorder, and may in future help identify those at greatest risk.
Published How alcohol consumption contributes to chronic pain (via sciencedaily.com) Original source
A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.
Published A gene involved in Down syndrome puts the brakes on neurons' activity in mice (via sciencedaily.com) Original source
Researchers have found that an extra copy of a gene in Down syndrome patients causes improper development of neurons in mice.
Published Impact of maternal stress during pregnancy on child's health (via sciencedaily.com) Original source
New research examines the impact that maternal stress during pregnancy has on the neuro-development of babies.
Published Drinking alcohol while breastfeeding impacts health of newborns (via sciencedaily.com) Original source
What are the consequences of mothers consuming alcohol while breastfeeding? A research team at the University of California, Riverside, performed a mouse study to find out.
Published Early signs that may help predict ADHD risk (via sciencedaily.com) Original source
Information available at birth may help to identify children with higher likelihood of developing ADHD, according to new research.
Published Father's alcohol consumption before conception linked to brain and facial defects in offspring (via sciencedaily.com) Original source
Research investigating fetal alcohol syndrome (FAS) exclusively examines maternal alcohol exposure. However, because men drink more and are more likely to binge drink than women, scientists set out to challenge the existing dogma, using a mouse model to examine what happens when the mother, father and both parents consume alcohol.
Published A miniature heart in a petri dish: Organoid emulates development of the human heart (via sciencedaily.com) Original source
A team has induced stem cells to emulate the development of the human heart. The result is a sort of 'mini-heart' known as an organoid. It will permit the study of the earliest development phase of our heart and facilitate research on diseases.
Published Boosting the body's anti-viral immune response may eliminate aging cells (via sciencedaily.com) Original source
Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.
Published Scientists see anti-aging potential in an invasive weed (via sciencedaily.com) Original source
The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.
Published Living with pet cats or dogs is associated with fewer food allergies in young children, study finds (via sciencedaily.com) Original source
In an analysis of over 65,000 infants from Japan, children exposed to pet cats or indoor dogs during fetal development or early infancy tended to have fewer food allergies compared to other children.
Published Lone star tick bites may be to blame for unexplained digestive problems (via sciencedaily.com) Original source
New clinical guidance has been developed to help physicians and patients identify if unexplained digestive symptoms are due to alpha-gal syndrome, a food allergy that is caused by lone star tick bites.