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Categories: Birth Defects, Fertility

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Fertility Pregnancy and Childbirth
Published

Oocytes outsmart toxic proteins to preserve long-term female fertility      (via sciencedaily.com)     Original source 

The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these toxic proteins also influences oocyte quality and female fertility. The researchers discovered that mouse oocytes have specialized structures which roam the cytoplasm and act like a clean-up crew which capture and hold onto protein aggregates, rendering them harmless. Failure to degrade the toxic proteins led to the formation of defective eggs. 3 in 5 (60%) of mouse embryos that inherited the toxic proteins failed to complete the very earlies stages of development. The study presents a new frontier to explore the underlying mechanisms of poor oocyte quality, which is the leading cause of female infertility.

Fertility Pregnancy and Childbirth
Published

Scientists discover new target for reversible, non-hormonal male birth control      (via sciencedaily.com)     Original source 

Scientists discovered a new target for reversible, non-hormonal male birth control. The drug, an HDAC inhibitor, blocked sperm production and fertility in male mice without affecting libido or future reproduction.

Birth Defects Child Development Children's Health Depression Infant's Health Mental Health Research Parenting Pregnancy and Childbirth Psychology Research Today's Healthcare
Published

Stress during pregnancy can lead to early maturation of first-born daughters      (via sciencedaily.com)     Original source 

Researchers have found a correlation between early signs of adrenal puberty in first-born daughters and their mothers' having experienced high levels of prenatal stress. They did not find the same result in boys or daughters who were not first-born.

Fertility
Published

What can bulls tell us about men?      (via sciencedaily.com)     Original source 

Researchers have found genes in the reproductive organs of bulls that influence fertility. The findings can be transferred to humans, as these genes are also present in men.

Fertility Pregnancy and Childbirth
Published

Male fertility gene discovery reveals path to success for sperm      (via sciencedaily.com)     Original source 

The discovery of a pair of genes that work in perfect harmony to protect male fertility could provide new insights into some unexplained cases of the most severe form of infertility, research suggests.

Birth Defects Infant's Health
Published

Why ventilators can be tough on preemie lungs      (via sciencedaily.com)     Original source 

New research finds that premature lungs become stiffer than adult lungs under stress. This disrupts the function of transporters that are important for removing water from the lungs after birth.

Children's Health Diet and Weight Loss Fertility Infant's Health Pregnancy and Childbirth
Published

Genetic cause of low birth weight among children conceived after fertility treatment      (via sciencedaily.com)     Original source 

A medical researcher has identified a genetic cause for the increased risk of low birth weight in babies born following assisted reproductive technologies such as IVF.

Birth Defects Child Development Infant's Health Parenting Psychology Research
Published

Patterns of brain connectivity differ between pre-term and term babies      (via sciencedaily.com)     Original source 

A new scanning study of 390 babies has shown distinct patterns between term and pre-term babies in the moment-to-moment activity and connectivity of brain networks.

Birth Defects Nutrition Pregnancy and Childbirth Staying Healthy
Published

Pregnant women should avoid ultraprocessed, fast foods, experts urge      (via sciencedaily.com)     Original source 

Research shows that phthalates, a class of chemicals associated with plastics, can shed from the wrapping, packaging and even from plastic gloves worn by food handlers into food. Once consumed during pregnancy, the chemicals can get into the bloodstream, through the placenta and then into the fetal bloodstream. The chemical can cause oxidative stress and an inflammatory cascade within the fetus, researchers noted. Previous literature has indicated that exposure to phthalates during pregnancy can increase the risk of low birth weight, preterm birth and child mental health conditions such as autism and ADHD.

Birth Defects Chronic Illness Depression Mental Health Research Pregnancy and Childbirth Psychology Research
Published

Researchers make progress toward developing blood tests for psychiatric and neurological disorders      (via sciencedaily.com)     Original source 

Researchers used genetic material from human blood and lab-grown brain cells say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.

Birth Defects Chronic Illness Diabetes Diet and Weight Loss Infant's Health Nutrition Obesity Pregnancy and Childbirth
Published

Males born to obese mothers more likely to suffer health issues as adults      (via sciencedaily.com)     Original source 

Males born to obese women are more likely to be overweight at birth and develop metabolic complications in later life, including liver disease and diabetes.

Fertility Healthy Aging Menopause Today's Healthcare Women's Health - General
Published

How ovarian tissue freezing could prevent menopause -- possibly forever      (via sciencedaily.com)     Original source 

A new paradigm around the biological processes of menopause is capturing the attention of scientists. The primary question: can menopause be delayed in healthy women, allowing them to extend their child-bearing years -- and perhaps even forestall some of the health risks and uncomfortable symptoms linked to plummeting estrogen levels?

Birth Defects Children's Health Chronic Illness Healthy Aging Psychology Research
Published

Polycystic ovary syndrome tied to memory, thinking problems      (via sciencedaily.com)     Original source 

People with polycystic ovary syndrome may be more likely to have memory and thinking problems in middle age, according to new research. The study does not prove that polycystic ovary syndrome causes cognitive decline. It only shows an association.

Birth Defects Psychology Research
Published

Brain protein's virus-like structure may help explain cancer-induced memory loss      (via sciencedaily.com)     Original source 

In a rare but serious complication of cancer, the body's own immune system can start attacking the brain, causing rapid-onset memory loss and cognitive deficits. What triggers this sudden biological civil war was largely unknown. Now, researchers have found that some tumors can release a protein that looks like a virus, kickstarting an out-of-control immune reaction that may damage brain cells.

Birth Defects Pregnancy and Childbirth
Published

Maternal pulse recording during childbirth prevents encephalopathy in newborn babies      (via sciencedaily.com)     Original source 

External heart rate monitoring, the most common method of monitoring the fetus, may leave signs of fetal hypoxia undetected if the maternal pulse rate is not simultaneously monitored. The risk is that the fetal heart rate is masked by the maternal pulse, with fetal distress going unnoticed.

Birth Defects Children's Health Infant's Health Today's Healthcare
Published

Rare disorder causing extra fingers and toes identified      (via sciencedaily.com)     Original source 

A rare disorder which causes babies to be born with extra fingers and toes and a range of birth defects has been identified in new research. The disorder, which has not yet been named, is caused by a genetic mutation in a gene called MAX. As well as extra digits -- polydactyly -- it leads to a range of symptoms relating to ongoing brain growth, such as autism. The research marks the first time this genetic link has been identified.

Birth Defects Gynecology Infant's Health Pregnancy and Childbirth
Published

Provides new explanation for why placenta may not properly separate at birth, putting mother and newborn at risk      (via sciencedaily.com)     Original source 

A new study may change the way clinicians and scientists understand, diagnose and treat placenta accreta spectrum disorder, a serious condition in which the placenta fails to separate from the uterus at birth, jeopardizing the life and health of both mother and baby.

Birth Defects Chronic Illness Infant's Health Pregnancy and Childbirth
Published

Gene behind heart defects in Down syndrome identified      (via sciencedaily.com)     Original source 

Researchers have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21. Reducing the overactivity of this gene partially reversed these defects in mice, setting the scene for potential future therapies for heart conditions in people with Down syndrome.

Birth Defects Infant's Health Pregnancy and Childbirth
Published

Ultrasounds can help predict the risk of preterm births      (via sciencedaily.com)     Original source 

Researchers have developed a way to use ultrasound to predict whether a pregnant person is at risk of delivering a baby prematurely, which occurs in upward of 10% of pregnancies in the U.S.

Birth Defects Diet and Weight Loss Infant's Health Pregnancy and Childbirth
Published

Exposure to flame retardants linked to premature birth, higher birth weight      (via sciencedaily.com)     Original source 

Exposure to organophosphate ester flame retardants during pregnancy is linked to premature births and greater fetal growth, according to a new study.