Showing 20 articles starting at article 1
Categories: Birth Defects, Skin Care
Published Human embryo-like models created from stem cells to understand earliest stages of human development
(via sciencedaily.com) Original source Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why and how pregnancies fail.
Published Innovative paper-like, battery-free, AI-enabled sensor for holistic wound monitoring
(via sciencedaily.com) Original source Scientists have invented a paper-like, battery-free, AI-enabled sensor patch -- PETAL -- for convenient and effective monitoring of wound recovery. This novel technology provides early warning of complications to improve wound care. The paper-like, battery-free PETAL sensor patch uses five colorimetric sensors to measure biomarkers in the wound within 15 mins. A proprietary AI algorithm quickly analyses the digital image of the sensor patch to determine wound healing status with an accuracy rate of 97%.
Published Study hints at how cancer immunotherapy can be safer
(via sciencedaily.com) Original source Cancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumors. Immunotherapies that block checkpoint receptors like PD-1, proteins that limit the capacity of T cells to attack tumors, have become the choice for the treatment of numerous types of solid cancer. However, the introduction of PD-1-blocking agents can often result in T cells attacking healthy tissues in addition to cancer cells, causing severe, sometimes life-threatening, side effects that can blunt the benefits of immunotherapy. A new study reveals new insights into how PD-1 functions to maintain healthy tissues, findings that can help scientists predict, treat, or even prevent the side effects of PD-1 blocking immunotherapies.
Published What role does alternative splicing play in neurodegenerative disease?
(via sciencedaily.com) Original source Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these disorders.
Published The IL-17 protein plays a key role in skin aging
(via sciencedaily.com) Original source A team of scientists has discovered that IL-17 protein plays a central role in skin aging. The study highlights an IL-17-mediated ageing process to an inflammatory state.
Published Poorly insulated nerve cells promote Alzheimer's disease in old age
(via sciencedaily.com) Original source Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
Published PAINTing a wound-healing ink into cuts with a 3D-printing pen
(via sciencedaily.com) Original source The body is pretty good at healing itself, though more severe wounds can require bandages or stitches. But researchers have now developed a wound-healing ink that can actively encourage the body to heal by exposing the cut to immune-system vesicles. The ink can be spread into a cut of any shape using a 3D-printing pen, and in mice, the technology nearly completely repaired wounds in just 12 days.
Published Open-analysis platform for pediatric brain tumors provides robust data resource for childhood cancer research
(via sciencedaily.com) Original source Researchers have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, researchers have used this platform to identify initial findings about genetic variants associated with poorer outcomes that could help guide future diagnostic and therapeutic advances.
Published Scientists unveil RNA-guided mechanisms driving cell fate
(via sciencedaily.com) Original source The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.
Published New type of drug candidate effectively accelerates wound healing in clinical study
(via sciencedaily.com) Original source Complicated, hard-to-heal wounds are a growing medical problem and there are currently only two drugs approved with proven efficacy. In a new study on humans, researchers show that treatment with a specific type of modified lactic acid bacteria works well and has a positive effect on the healing of wounds.
Published One step closer to developing a potentially ultraprotective sunscreen from our own melanin
(via sciencedaily.com) Original source Researchers have announced a major advance in understanding the fundamental structure of melanin and one of its components that turns light into heat, protecting the body from sun damage.
Published Non-antibiotic treatment for women with persistent acne shown to be effective
(via sciencedaily.com) Original source A team of researchers has shown that a cheap and readily available drug, used to treat high blood pressure, could help the thousands of women who suffer from persistent acne.
Published Understanding the speed of brain communication
(via sciencedaily.com) Original source Called the human connectome, this structural system of neural pathways develops as people age. A new study shows transmission speed among brain regions increases into early adulthood. Learning more about neuron transmission may improve the understanding of psychological disorders.
Published A special omega-3 fatty acid lipid will change how we look at the developing and aging brain
(via sciencedaily.com) Original source Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.
Published Gene responsible for severe facial defects identified
(via sciencedaily.com) Original source Goldenhar syndrome is a rare congenital disease, affecting early fetal development. This syndrome includes malformations of varying severity, affecting different parts of the face. Its causes and modes of transmission are still poorly understood. An international collaboration has discovered that pathogenic variants of the FOXI3 gene -- responsible for the development of the ear -- cause one form of this developmental disorder. The scientists were also able to identify the modes of transmission of the disease when this particular gene is involved.
Published Researchers reveal an ancient mechanism for wound repair
(via sciencedaily.com) Original source The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Problems with 'pruning' brain connections linked to adolescent mental health disorders
(via sciencedaily.com) Original source Problems with the brain's ability to 'prune' itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today. The findings may help explain why people are often affected by more than one mental health disorder, and may in future help identify those at greatest risk.
Published How alcohol consumption contributes to chronic pain
(via sciencedaily.com) Original source A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.
Published A gene involved in Down syndrome puts the brakes on neurons' activity in mice
(via sciencedaily.com) Original source Researchers have found that an extra copy of a gene in Down syndrome patients causes improper development of neurons in mice.
Published Wearable patch can painlessly deliver drugs through the skin
(via sciencedaily.com) Original source A wearable patch applies painless ultrasonic waves to the skin, creating tiny channels that drugs can pass through.