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Categories: Birth Defects, Pregnancy and Childbirth

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Healthy Aging Pregnancy and Childbirth Today's Healthcare
Published

Researchers find that accelerated aging biology in the placenta contributes to a rare form of pregnancy-related heart failure      (via sciencedaily.com)     Original source 

In a new study, researchers show that elevated levels of proteins related to cellular senescence, or aging, in the blood and the placenta are linked to this form of heart failure.

Birth Defects
Published

Genetic variant identified that shaped the human skull base      (via sciencedaily.com)     Original source 

Researchers have identified a variant in the gene TBX1 as key in the development of the unique morphology at the base of the skull. TBX1 is present at higher levels in humans than in closely related hominins. Low TBX1 also occurs in certain genetic conditions causing altered skull base morphology. This study provides a greater understanding of human disease and evolution.

Birth Defects Chronic Illness Today's Healthcare
Published

Adults with congenital heart disease faced higher risk of abnormal heart rhythms      (via sciencedaily.com)     Original source 

Adults with congenital heart defects were more likely to experience an abnormal, irregular heartbeat, finds a new study.

Diabetes Pregnancy and Childbirth
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New study focuses on the placenta for clues to the development of gestational diabetes      (via sciencedaily.com)     Original source 

A new study has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.

Birth Defects Children's Health Psychology Research Schizophrenia
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Two key brain systems are central to psychosis      (via sciencedaily.com)     Original source 

When the brain has trouble filtering incoming information and predicting what's likely to happen, psychosis can result, research shows.

Chronic Illness Pregnancy and Childbirth Today's Healthcare
Published

Hypertensive disorders of pregnancy increase risk of cardiovascular death after giving birth      (via sciencedaily.com)     Original source 

Health researchers identify patients at risk for preventable death in the year after pregnancy.

Children's Health Diabetes Pregnancy and Childbirth
Published

Global research team finds no clear link between maternal diabetes during pregnancy and ADHD in children      (via sciencedaily.com)     Original source 

An international research team has just provided valuable evidence through a 20-year longitudinal study to address the longstanding debate concerning the potential impact of maternal diabetes on attention-deficit/hyperactivity disorder (ADHD) in children. This study, analysing real-world data from over 3.6 million mother-baby pairs in China's Hong Kong, Taiwan, New Zealand, Finland, Iceland, Norway and Sweden, showed that maternal diabetes during pregnancy is unlikely to be a direct cause of ADHD.

Birth Defects Healthy Aging
Published

Impact of aldehydes on DNA damage and aging      (via sciencedaily.com)     Original source 

Researchers have discovered the connection between aldehydes, organic compounds produced by cells as part of metabolic processes, and rapid aging. Their findings indicate a potential treatment for diseases that lead to accelerated aging as well as a means to counteract aging in healthy people by controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.

Child Development Children's Health Pregnancy and Childbirth Today's Healthcare
Published

No link between acetaminophen use during pregnancy and children's risk of autism, ADHD, and intellectual disability, says large sibling study      (via sciencedaily.com)     Original source 

In the largest study to date on the subject, researchers found no evidence to support a causal link between acetaminophen use during pregnancy and increased risk of autism, ADHD and intellectual disability in children. The findings use data from a nationwide cohort of over 2.4 million children born in Sweden, including siblings not exposed to the drug before birth.

Birth Defects Psychology Research
Published

Are lab-grown brain tissues ethical? There is no no-brainer answer      (via sciencedaily.com)     Original source 

Researchers offer insights into the ethical dilemmas and legal complexities surrounding brain organoids, especially those derived from human fetal tissue. Their findings advocate for thorough regulatory frameworks to ensure that scientific and medical progress in this field is conducted responsibly and ethically, with strong regulations supported by sound ethical and legal principles.

Healthy Aging Pregnancy and Childbirth Today's Healthcare
Published

Pregnancy accelerates biological aging in a healthy, young adult population      (via sciencedaily.com)     Original source 

Pregnancy may carry a cost, reports a new study. The research shows that women who reported having been pregnant looked biologically older than women who had never been pregnant, and women who had been pregnant more often looked biologically older than those who reported fewer pregnancies.

Birth Defects Chronic Illness
Published

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases      (via sciencedaily.com)     Original source 

Scientists report that a progressive neurodegenerative disease can be triggered by a viral infection. The mechanism relates to mitochondrial roles in antiviral defense mechanisms.

Birth Defects Child Development Children's Health Infant and Preschool Learning Infant's Health Nutrition Parenting Pregnancy and Childbirth
Published

Even moderate alcohol usage during pregnancy linked to birth abnormalities      (via sciencedaily.com)     Original source 

Researchers have found that even low to moderate alcohol use by pregnant patients may contribute to subtle changes in their babies' prenatal development, including lower birth length and a shorter duration of gestation.

Birth Defects Children's Health Chronic Illness
Published

YKT6 gene variants cause a new genetic disorder finds a new study      (via sciencedaily.com)     Original source 

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

Diet and Weight Loss Infant's Health Obesity Pregnancy and Childbirth
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Women with obesity do not need to gain weight during pregnancy, new study suggests      (via sciencedaily.com)     Original source 

The guidelines for weight gain during pregnancy in obese women have long been questioned. New research supports the idea of lowering or removing the current recommendation of a weight gain of at least 5 kg.

Depression Menopause Mental Health Research Pregnancy and Childbirth Today's Healthcare
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Positive associations between premenstrual disorders and perinatal depression      (via sciencedaily.com)     Original source 

Women affected by premenstrual disorders have a higher risk of perinatal depression compared with those who do not, according to new research. The relationship works both ways: those with perinatal depression are also more likely to develop premenstrual disorders after pregnancy and childbirth. This study suggests that a common mechanism might contribute to the two conditions.

Birth Control Diabetes Pregnancy and Childbirth Today's Healthcare
Published

Miscarriages linked to health risks in later pregnancies      (via sciencedaily.com)     Original source 

Researchers analyzed 52 studies involving more than 4 million pregnancies across 22 countries to investigate the health impacts of miscarriage, abortion and recurrent pregnancy loss (more than two miscarriages in succession) on subsequent pregnancies. The study found different health risks for each group.

Birth Defects
Published

Synaptic protein change during development offers clues on evolution and disease      (via sciencedaily.com)     Original source 

An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The findings offer first insights into the mechanism behind synaptic development and open up routes for research on possible treatments.

Birth Defects
Published

Study of different autism types finds shared mechanism that may respond to drugs      (via sciencedaily.com)     Original source 

An analysis of how brains with different forms of autism develop has revealed common underlying mechanisms that may respond to existing medications.

Pregnancy and Childbirth
Published

Stem cell model offers first glimpse of early human embryonic development      (via sciencedaily.com)     Original source 

The new platform's ethically grounded approach promises to reveal much about how human embryos form during the earliest stages of pregnancy.