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Categories: Birth Defects, Diabetes

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Diabetes Today's Healthcare
Published

Shoe technology reduces risk of diabetic foot ulcers      (via sciencedaily.com)     Original source 

Researchers have developed a new shoe insole technology that helps reduce the risk of diabetic foot ulcers, a dangerous open sore that can lead to hospitalization and leg, foot or toe amputations.

Diabetes
Published

Siblings with unique genetic change help scientists progress drug search for type 1 diabetes      (via sciencedaily.com)     Original source 

Two siblings who have the only known mutations in a key gene anywhere in the world have helped scientists gain new insights that could help progress the search for new treatments in type 1 diabetes.

Birth Defects
Published

Genetic variant identified that shaped the human skull base      (via sciencedaily.com)     Original source 

Researchers have identified a variant in the gene TBX1 as key in the development of the unique morphology at the base of the skull. TBX1 is present at higher levels in humans than in closely related hominins. Low TBX1 also occurs in certain genetic conditions causing altered skull base morphology. This study provides a greater understanding of human disease and evolution.

Birth Defects Chronic Illness Today's Healthcare
Published

Adults with congenital heart disease faced higher risk of abnormal heart rhythms      (via sciencedaily.com)     Original source 

Adults with congenital heart defects were more likely to experience an abnormal, irregular heartbeat, finds a new study.

Diabetes Pregnancy and Childbirth
Published

New study focuses on the placenta for clues to the development of gestational diabetes      (via sciencedaily.com)     Original source 

A new study has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.

Diabetes Diet and Weight Loss Nutrition Obesity
Published

Scientists uncover a missing link between poor diet and higher cancer risk      (via sciencedaily.com)     Original source 

A research team has unearthed new findings which may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from poor diet. The insights gained from this study hold promise for advancing cancer prevention strategies aimed at promoting healthy aging.

Birth Defects Children's Health Psychology Research Schizophrenia
Published

Two key brain systems are central to psychosis      (via sciencedaily.com)     Original source 

When the brain has trouble filtering incoming information and predicting what's likely to happen, psychosis can result, research shows.

Diabetes Diet and Weight Loss Obesity
Published

This outdated diabetes drug still has something to offer      (via sciencedaily.com)     Original source 

Researchers have discovered the biochemical workings of an old-fashioned diabetes drug, and it's helping them develop new, safer alternatives.

Diabetes Fitness
Published

Does the time of day you move your body make a difference to your health?      (via sciencedaily.com)     Original source 

Undertaking the majority of daily physical activity in the evening is linked to the greatest health benefits for people living with obesity, according to researchers who followed the trajectory of 30,000 people over almost 8 years.

Children's Health Diabetes Pregnancy and Childbirth
Published

Global research team finds no clear link between maternal diabetes during pregnancy and ADHD in children      (via sciencedaily.com)     Original source 

An international research team has just provided valuable evidence through a 20-year longitudinal study to address the longstanding debate concerning the potential impact of maternal diabetes on attention-deficit/hyperactivity disorder (ADHD) in children. This study, analysing real-world data from over 3.6 million mother-baby pairs in China's Hong Kong, Taiwan, New Zealand, Finland, Iceland, Norway and Sweden, showed that maternal diabetes during pregnancy is unlikely to be a direct cause of ADHD.

Birth Defects Healthy Aging
Published

Impact of aldehydes on DNA damage and aging      (via sciencedaily.com)     Original source 

Researchers have discovered the connection between aldehydes, organic compounds produced by cells as part of metabolic processes, and rapid aging. Their findings indicate a potential treatment for diseases that lead to accelerated aging as well as a means to counteract aging in healthy people by controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.

Diabetes
Published

Beating back bitter taste in medicine      (via sciencedaily.com)     Original source 

The bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are particularly sensitive to bitter taste. A team found that the diabetes drug rosiglitazone could partially block the bitter taste of some especially bad-tasting medications. The hope is that repurposed drugs could be added in small doses to other medicines to make them less bitter and taste better, thereby encouraging compliance with bitter drug regimens.

Birth Defects Psychology Research
Published

Are lab-grown brain tissues ethical? There is no no-brainer answer      (via sciencedaily.com)     Original source 

Researchers offer insights into the ethical dilemmas and legal complexities surrounding brain organoids, especially those derived from human fetal tissue. Their findings advocate for thorough regulatory frameworks to ensure that scientific and medical progress in this field is conducted responsibly and ethically, with strong regulations supported by sound ethical and legal principles.

Diabetes Diet and Weight Loss Obesity Today's Healthcare
Published

Few newly diagnosed type 2 diabetics succeed in losing weight -- weight gain linked to much higher risk of complications      (via sciencedaily.com)     Original source 

A register-based study identified three distinct BMI trajectory groups among patients with newly diagnosed type 2 diabetes. In a four-year follow-up, most patients followed a stable trajectory without much weight change. Only 10% of patients lost weight, whereas 3% gained weight. Mean BMI exceeded the threshold of obesity in all groups at baseline. Weight loss is a central treatment goal in type 2 diabetes, but the study shows that few patients succeed in it.

Birth Defects Chronic Illness
Published

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases      (via sciencedaily.com)     Original source 

Scientists report that a progressive neurodegenerative disease can be triggered by a viral infection. The mechanism relates to mitochondrial roles in antiviral defense mechanisms.

Diabetes Today's Healthcare
Published

Study finds less invasive, safer option for removing benign pancreatic tumors      (via sciencedaily.com)     Original source 

Researchers describe a new technique for the minimally invasive removal of benign tumors located in the challenging posterior head of the pancreas (right side of abdomen, nestled in the curve of the duodenum (or first part of the small intestine). The technique, called the retro-laparoscopic approach, allows surgeons to safely and effectively remove these tumors without removing healthy pancreatic tissue, thereby preserving organ functionality.

Child Development Diabetes
Published

Large language models respond differently based on user's motivation      (via sciencedaily.com)     Original source 

A new study reveals how large language models (LLMs) respond to different motivational states. In their evaluation of three LLM-based generative conversational agents (GAs)--ChatGPT, Google Bard, and Llama 2, scientists found that while GAs are able to identify users' motivation states and provide relevant information when individuals have established goals, they are less likely to provide guidance when the users are hesitant or ambivalent about changing their behavior.

Birth Defects Child Development Children's Health Infant and Preschool Learning Infant's Health Nutrition Parenting Pregnancy and Childbirth
Published

Even moderate alcohol usage during pregnancy linked to birth abnormalities      (via sciencedaily.com)     Original source 

Researchers have found that even low to moderate alcohol use by pregnant patients may contribute to subtle changes in their babies' prenatal development, including lower birth length and a shorter duration of gestation.

Birth Defects Children's Health Chronic Illness
Published

YKT6 gene variants cause a new genetic disorder finds a new study      (via sciencedaily.com)     Original source 

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.