Showing 20 articles starting at article 1
Published Scientists take next big step in understanding genetics of schizophrenia (via sciencedaily.com) Original source
Scientists are figuring out which of the 5,000 variants associated with schizophrenia have an actual causal effect in the development of the condition that affects millions of people worldwide.
Published Schizophrenia genetic risk factor impairs mitochondrial function (via sciencedaily.com) Original source
Researcher discovers possible link of mitochondrial function to the development of schizophrenia.
Published New neuroimaging approach could improve diagnosis of schizophrenia (via sciencedaily.com) Original source
New research has identified age-related changes in brain patterns associated with the risk for developing schizophrenia. The discovery could help clinicians identify the risk for developing mental illness earlier and improve treatment options.
Published Schizophrenia is associated with somatic mutations occurring in utero (via sciencedaily.com) Original source
As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. Researchers have now found a correlation between schizophrenia and somatic copy-number variants, a type of mutation that occurs early in development but after genetic material is inherited. This study is one of the first to rigorously describe the relationship between somatic -- not inherited -- genetic mutations and schizophrenia risk.
Published How does dopamine regulate both learning and motivation? (via sciencedaily.com) Original source
A new study brings together two schools of thought on the function of the neurotransmitter dopamine: one saying that dopamine provides a learning signal, the other saying that dopamine drives motivation.
Published Further link identified between autoimmunity and schizophrenia (via sciencedaily.com) Original source
Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies. Researchers have now identified autoantibodies that target a 'synaptic adhesion protein' in a subset of patients with schizophrenia. When injected into mice, the autoantibodies caused many schizophrenia-related changes.
Published Vitamin D alters developing neurons in the brain's dopamine circuit (via sciencedaily.com) Original source
Neuroscientists have shown how vitamin D deficiency affects developing neurons in the brain's dopamine circuit, which may lead to the dopamine dysfunction seen in adults with schizophrenia.
Published A special omega-3 fatty acid lipid will change how we look at the developing and aging brain (via sciencedaily.com) Original source
Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.
Published Exposure therapy to feared foods may help kids with eating disorders (via sciencedaily.com) Original source
Whether you're afraid of dogs, needles or enclosed spaces, one of the most effective interventions for this type of anxiety disorder is exposure therapy in which you confront your fear in a safe environment. A new study finds that exposure therapy is also a promising treatment for adolescents with eating disorders. They found that exposure to feared foods -- such as candy bars and pizza -- helped kids who were in a partial hospitalization program for eating disorders experience decreased anxiety toward food.
Published The drug fasudil is found to reverse key symptoms of schizophrenia in mice (via sciencedaily.com) Original source
Researchers used the drug fasudil to restore neurons and improve methamphetamine-induced cognitive dysfunction in a mouse model of schizophrenia.
Published Abnormal 12-hour cyclic gene activity found in schizophrenic brains (via sciencedaily.com) Original source
Researchers present the first evidence of 12-hour cycles of gene activity in the human brain. The study also reveals that some of those 12-hour rhythms are missing or altered in the postmortem brains of patients with schizophrenia.
Published Body Dissatisfaction Can Lead to Eating Disorders at Any Age (via sciencedaily.com) Original source
Eating disorders are stereotypically associated with adolescents and young adults. Growing evidence, however, suggests that these conditions can occur at any time during a woman's lifespan, including at midlife. A new study finds that body dissatisfaction is a primary cause of eating disorders, especially during perimenopause.
Published Scientists uncover possible neural link between early life trauma and binge-eating disorder (via sciencedaily.com) Original source
Research has revealed how a pathway in the brain that typically provides signals to stop eating may be altered by early life trauma. The discovery, obtained from studies in mice adds new perspective to binge eating and obesity.
Published Scientists link rare genetic phenomenon to neuron function, schizophrenia (via sciencedaily.com) Original source
Using state-of-the-art whole-genome sequencing and machine learning techniques, researchers conducted one of the first and the largest investigations of tandem repeats in schizophrenia, elucidating their contribution to the development of this devastating disease.
Published ADHD medication for amphetamine addiction linked to reduced risk of hospitalization and death, study finds (via sciencedaily.com) Original source
The ADHD medication lisdexamfetamine was associated with the lowest risk of hospitalization and death in people with amphetamine addiction, when medications generally used among persons with substance use disorders were compared, according to a new study.
Published Inflammation amplifies the effect of genetic risk variants for schizophrenia (via sciencedaily.com) Original source
Schizophrenia patients have fewer connections between nerve cells. This is believed to be caused by genetic risk variants leading to an excessive elimination of nerve cell connections by the immune cells of the brain. Researchers now report that the levels of protein from the relevant risk gene are elevated in first-episode patients and that inflammation further increases the expression of the risk gene.
Published Schizophrenia may increase dementia risk by 2.5 times (via sciencedaily.com) Original source
People with psychotic disorders such as schizophrenia are 2.5 times more likely than those without a psychotic disorder to eventually develop dementia, according to a new review.
Published Circadian rhythm disruption found to be common among mental health disorders (via sciencedaily.com)
Scientists hypothesize that circadian rhythm disruption is a psychopathology factor shared by a broad range of mental illnesses and that research into its molecular foundation could be key to unlocking better therapies and treatments.
Published Deep brain stimulation shows promise against binge eating disorder (via sciencedaily.com) Original source
A small device that detects food craving-related brain activity in a key brain region, and responds by electrically stimulating that region, has shown promise in a pilot clinical trial in two patients with loss-of-control binge eating disorder (BED), according to researchers.
Published Neuronal cell type for controlling the flow of information in the brain (via sciencedaily.com)
Researchers have identified specific cells that regulate the transmission of information between brain areas. This discovery forms the basis for the development of new treatment options for neuropsychiatric disorders which are characterized by impaired coordination of information flow in the brain.