Showing 20 articles starting at article 1
Published Similarities and differences in human and insect vision formation (via sciencedaily.com) Original source
Researchers have discovered profound similarities and surprising differences between humans and insects in the production of the critical light-absorbing molecule of the retina, 11-cis-retinal, also known as the 'visual chromophore.' The findings deepen understanding of how mutations in the RPE65 enzyme cause retinal diseases, especially Leber congenital amaurosis, a devastating childhood blinding disease.
Published Could ultra-processed foods be the new 'silent' killer? (via sciencedaily.com) Original source
Hundreds of novel ingredients never encountered by human physiology are now found in nearly 60 percent of the average adult's diet and nearly 70 percent of children's diets in the U.S. An emerging health hazard is the unprecedented consumption of these ultra-processed foods in the standard American diet. This may be the new 'silent' killer, as was unrecognized high blood pressure in previous decades. Physicians provide important insights in a battle where the entertainment industry, the food industry and public policy do not align with their patients' needs.
Published Eating too much protein is bad for your arteries, and this amino acid is to blame (via sciencedaily.com) Original source
Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.
Published Link between high levels of niacin -- a common B vitamin -- and heart disease, study suggests (via sciencedaily.com) Original source
Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease. Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies. The researchers also showed in preclinical studies that 4PY directly triggers vascular inflammation which damages blood vessels and can lead to atherosclerosis over time.
Published Protein-rich breakfast boosts satiety and concentration (via sciencedaily.com) Original source
A new study has explored the link between diet and cognitive function, and the results reveal that a protein-rich breakfast can increase satiety and improve concentration. This is important knowledge in a society with increasing obesity rates and lifestyle-related diseases.
Published Blocking an essential nutrient inhibits malaria parasite growth (via sciencedaily.com) Original source
Researchers found that by preventing the malaria parasite from scavenging fatty acids, a type of required nutrient, it could no longer grow.
Published Heart organoids simulate pregestational diabetes-induced congenital heart disease (via sciencedaily.com) Original source
An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. The findings also showed that endoplasmic reticulum (ER) stress and lipid imbalance are critical factors contributing to these disorders, which could be ameliorated with exposure to omega-3s.
Published Understanding rapid weight loss in older women: Message from the heart (via sciencedaily.com) Original source
Unexplained rapid weight loss in older people could be a sign of underlying disease and can be linked with increased risk of falls and fractures, as well as a poorer long-term prognosis.
Published Archaeological evidence of seasonal vitamin D deficiency discovered (via sciencedaily.com) Original source
Rickets ran rife in children following the Industrial Revolution, but new research has found factory work and polluted cities aren't entirely to blame for the period's vitamin D deficiencies.
Published Study urges people to think twice before going on a diet (via sciencedaily.com) Original source
A new qualitative study highlights the negative interpersonal and psychological consequences associated with 'yo-yo dieting,' also known as weight cycling. The work underscores how toxic yo-yo dieting can be and how difficult it can be for people to break the cycle.
Published 'Furry fruit' improves mental health -- fast (via sciencedaily.com) Original source
Kiwifruit has proven itself as a powerful mood booster and new research has shown just how fast its effects can be.
Published Third major study finds evidence that daily multivitamin supplements improve memory and slow cognitive aging in older adults (via sciencedaily.com) Original source
Researchers tested the effects of a daily multivitamin on cognitive changes in a study of 573 participants with in-person visits in the COSMOS trial. The researchers also conducted a meta-analysis among over 5,000 non-overlapping participants across the three separate cognition studies within the COSMOS trial. Results showed a statistically significant benefit for cognition among participants taking the multi-vitamin compared to placebo, suggesting that a multi-vitamin could help prevent memory loss and slow cognitive aging among older adults.
Published Energy-starved breast cancer cells consume their surroundings for fuel (via sciencedaily.com) Original source
Breast cancer cells ingest and consume the matrix surrounding them to overcome starvation, according to a new study. The finding elucidates a previously unknown mechanism of cancer cell survival, and may offer a new target for therapy development.
Published A novel pathway regulating lipid biosynthesis by fatty acids (via sciencedaily.com) Original source
Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published New study reveals high prevalence of anemia with low rates of screening (via sciencedaily.com) Original source
A new study has found high rates of anemia among patients in the Irish health system, while screening for common causes was found to be low.
Published Scientists identify how dietary restriction slows brain aging and increases lifespan (via sciencedaily.com) Original source
Restricting calories is known to improve health and increase lifespan, but much of how it does so remains a mystery, especially in regard to how it protects the brain. Scientists have now uncovered a role for a gene called OXR1 that is necessary for the lifespan extension seen with dietary restriction and is essential for healthy brain aging.
Published Drugs used to treat Type 2 diabetes reduce alcohol cravings, use in individuals with obesity (via sciencedaily.com) Original source
An analysis of those posts, together with a remote study of individuals with obesity who reported using semaglutide and tirzepatide, found that the drugs decreased cravings and reduced alcohol consumption, according to a new study.
Published Hearing loss increases the risk of dementia (via sciencedaily.com) Original source
In a new study featuring data from 573,088 people, researchers have found a link between hearing loss and the development of dementia. The study is the largest of its kind to date.
Published Foundation laid for improved diagnostic imaging of brain tumors (via sciencedaily.com) Original source
Research team draws up criteria for PET-based examinations of malignant brain tumors.
Published Aptamers: lifesavers; ion shields: aptamer guardians (via sciencedaily.com) Original source
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal and chemical stability as well as ability to inhibit specific enzymes or target proteins through three-dimensional binding. They also hold promise for swift diagnoses of colon cancer and other challenging diseases by targeting elusive biomarkers. Despite their utility, these aptamers are susceptible to easy degradation by multiple enzymes, presenting a significant challenge.