Showing 20 articles starting at article 1
Published Study shows millions of people live with co-occuring chronic pain and mental health symptoms (via sciencedaily.com)
New research found that nearly 1 in 20 adults in the U.S. experience the co-occurrence of chronic pain and anxiety or depression, resulting in functional limitations in daily life.
Published A promising drug candidate for ALS -- prolongs lifespan and eases symptoms in rats and mice (via sciencedaily.com)
A research group has found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS). Cerebral dopamine neurotrophic factor CDNF prolongs the lifespan of and alleviates disease symptoms in rats and mice in animal studies.
Published Posttraumatic brain activity predicts resilience to PTSD (via sciencedaily.com)
After a traumatic experience, most people recover without incident, but some people -- between 2% and 10% -- develop posttraumatic stress disorder (PTSD), a mental health condition that can cause debilitating symptoms of anxiety due to emotional dysregulation. PTSD symptoms are present in up to 40% of trauma survivors in the acute aftermath of trauma, but full-blown PTSD develops in only a small subset of cases. Early identification of those at risk is critical for both early treatment and possible prevention.
Published Compound derived from hops reduces abundance of gut microbe associated with metabolic syndrome (via sciencedaily.com)
Researchers have shown in a mouse model and lab cultures that a compound derived from hops reduces the abundance of a gut bacterium associated with metabolic syndrome.
Published Cognitive behavioral therapy eases how fibromyalgia pain is experienced by the brain (via sciencedaily.com)
Patients living with fibromyalgia (FM) -- a disease that predominantly affects women and is characterized by chronic pain, fatigue and brain fog -- often find limited treatment options and a scarcity of explanations for their symptoms. Investigators have now found that cognitive behavioral therapy (CBT) can significantly reduce the burden of FM by, in part, reducing pain-catastrophizing, a negative cognitive and emotional response that can intensify pain through feelings of helplessness, rumination and intrusive thoughts. This finding is backed by neuroimaging data, evidencing reduced connectivity between regions of the brain associated with self-awareness, pain and emotional processing.
Published Job strain combined with high efforts and low reward doubled men's heart disease risk (via sciencedaily.com)
Men exposed to stressful working conditions who also felt that they put forth high effort but received low reward had twice the risk of heart disease compared to men who were free of those psychosocial stressors.
Published New blood marker can identify Parkinsonian diseases (via sciencedaily.com)
Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the brain? Yes, that's what a research group is discovering. 'We have observed that an enzyme in cerebrospinal fluid and in blood is a useful marker for identifying all types of Parkinson's-related diseases with high accuracy,' says the study leader.
Published Telecare cuts costs, boosts quality of life for dementia patients (via sciencedaily.com)
A telecare program that improves outcomes for patients with dementia and lightens the load for unpaid caregivers also has the surprising bonus of cutting Medicare costs, according to new research.
Published Study shows nearly 300% increase in ADHD medication errors (via sciencedaily.com)
Researchers investigated the characteristics and trends of out-of-hospital ADHD medication errors among people younger than 20 years old reported to U.S. poison centers from 2000 through 2021.
Published Guidelines follow advances in ALS gene discovery, ongoing gene therapy trials (via sciencedaily.com)
Researchers have developed an evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.
Published Older adults with digestive diseases experience higher rates of loneliness, depression (via sciencedaily.com)
A team of gastroenterologists and hepatologists examine psychosocial factors in older Americans with gastrointestinal conditions.
Published Your body's own cannabinoid molecules calm you during stress (via sciencedaily.com)
When you're under stress, your brain may release its own cannabinoid molecules to calm you, activating the same brain receptors as THC derived from cannabis plants. But the brain activity regulated by these cannabinoid molecules were not well known. A new study in mice has discovered a key emotional brain center, the amygdala, releases cannabinoid molecules under stress that dampen the incoming stress alarm from the hippocampus, a memory and emotion center in the brain. The finding may reveal novel therapeutic targets for the treatment of stress-related disorders.
Published New insights into the development of Parkinson's disease in the brain (via sciencedaily.com)
Researchers have identified a new pathological mechanism for a familial type of Parkinson's disease caused by a mutation in the CHCHD2 gene. Mutant CHCHD2 protein is mislocalized in cells and leads to alpha-synuclein protein aggregates via interactions with another protein, known as Csnk1e/d. These findings indicate that Csnk1e/d inhibition may slow or halt Parkinson's disease development in patients with CHCHD2 mutations, providing new hope for affected families.
Published Online AI-based test for Parkinson's disease severity shows promising results (via sciencedaily.com)
A new artificial intelligence tool can help people with Parkinson's disease remotely assess the severity of their symptoms within minutes. While expert neurologists performed slightly better than the AI model, the AI model outperformed the primary care physicians with UPDRS certification.
Published New Chagas research unravels decades-long mystery of how the tropical disease progresses (via sciencedaily.com)
New research shows that being infected with multiple strains of the Chagas-inducing parasite may hinder the disease's progression.
Published Active children are more resilient (via sciencedaily.com)
The school year has hardly begun and the first exams are already approaching. According to findings by researchers from the University of Basel, school children cope better with the stress if they get plenty of daily exercise.
Published AI helps ID cancer risk factors (via sciencedaily.com)
A novel study has identified a range of metabolic biomarkers that could help predict the risk of cancer.
Published Acting fast when an epidemic hits (via sciencedaily.com)
Researchers have developed a method for forecasting the short-term progression of an epidemic using extremely limited amounts of data.
Published Promising evidence for sickle cell gene therapy (via sciencedaily.com)
A clinical trial has tested a potentially curative stem cell gene therapy for sickle cell disease. The results were promising.
Published New blood test detects a key indicator of Parkinson's disease (via sciencedaily.com)
Researchers have developed a blood test that detects Parkinson's disease, potentially establishing a way to help diagnose the condition before nervous system damage worsens. A new blood-based diagnostic test would be a major advancement for Parkinson's disease, which afflicts 10 million people worldwide and is the second-most common neurodegenerative disease after Alzheimer's.