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Categories: Bipolar Disorder, Schizophrenia

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Bipolar Disorder Children's Health Chronic Illness Depression Mental Health Research
Published

Understanding the relationship between our sleep, body clock and mental health      (via sciencedaily.com)     Original source 

Problems with our sleep and internal body clock can trigger or worsen a range of psychiatric disorders, according to a new review of recent research evidence. The review suggests gaining a better understanding of the relationship between sleep, circadian rhythms and mental health could unlock new holistic treatments to alleviate mental health problems.

Children's Health Mental Health Research Psychology Research Schizophrenia
Published

Bullied teens' brains show chemical change associated with psychosis      (via sciencedaily.com)     Original source 

Researchers have found that adolescents being bullied by their peers are at greater risk of the early stages of psychotic episodes and in turn experience lower levels of a key neurotransmitter in a part of the brain involved in regulating emotions. The finding suggests that this neurotransmitter may be a potential target for pharmaceutical interventions aimed at reducing the risk of psychotic disorders.

Healthy Aging Neuropathy Psychology Research Schizophrenia
Published

Firing nerve fibers in the brain are supplied with energy on demand      (via sciencedaily.com)     Original source 

To rapidly transmit electrical signals in the brain, the long nerve fibers are insulated by specialized cells called oligodendrocytes. These cells also respond to the electrical signals of active nerve fibers and provide them with energy on demand, as researchers have discovered. If this process, regulated by potassium, is disabled in mice, the nerve fibers are severely damaged as the animals age -- resembling the defects of neurodegenerative diseases.

Schizophrenia Today's Healthcare
Published

Vigilant monitoring is needed to manage cardiac risks in patients using antipsychotics, doctors say      (via sciencedaily.com)     Original source 

The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study. Caution is advised to manage cardiac risks in patients prescribed these medications, the authors of the study and an accompanying editorial say.

Chronic Illness Psychology Research Schizophrenia
Published

Study reveals function of little-understood synapse in the brain      (via sciencedaily.com)     Original source 

New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma. Neuroscientists focused on the synapse connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells. OPCs can differentiate into oligodendrocytes, which produce a sheath around nerves known as myelin. Myelin is the protective sheath covering each nerve cell's axon -- the threadlike portion of a cell that transmits electrical signals between cells.

Schizophrenia Today's Healthcare
Published

Clinical predictive models created by AI are accurate but study-specific, researchers find      (via sciencedaily.com)     Original source 

Scientists were able to show that statistical models created by artificial intelligence (AI) predict very accurately whether a medication responds in people with schizophrenia. However, the models are highly context-dependent and cannot be generalized.

Schizophrenia Today's Healthcare
Published

Quest for personalized medicine hits a snag      (via sciencedaily.com)     Original source 

The quest for personalized medicine, a medical approach in which practitioners use a patient's unique genetic profile to tailor individual treatment, has emerged as a critical goal in the health care sector. But a new study shows that the mathematical models currently available to predict treatments have limited effectiveness.

Bipolar Disorder Children's Health Chronic Illness Depression Mental Health Research Today's Healthcare
Published

Bipolar disorder linked to early death      (via sciencedaily.com)     Original source 

Having bipolar disorder -- a serious mental illness that can cause both manic and depressed moods -- can make life more challenging. It also comes with a higher risk of dying early. Now, a study puts into perspective just how large that risk is, and how it compares with other factors that can shorten life.

Bipolar Disorder Children's Health Depression Mental Health Research
Published

Connection between light levels and mental health -- climate change could also have an impact in the future      (via sciencedaily.com)     Original source 

In Finland, there is a clear increase in the number of sick days taken due to depression, anxiety and sleep disorders in October and November, whereas the number of absences is lower than expected between June and September. In late autumn, the number of sick days taken is almost twice as high as in the summer and about a quarter higher than in early autumn. On the other hand, manic episodes related to bipolar disorder occur more frequently than expected during the spring and summer, when there are more daylight hours, and less frequently than expected during darker times of year.

Child Development Mental Health Research Schizophrenia
Published

Unravelling the association between neonatal proteins and adult health      (via sciencedaily.com)     Original source 

Scientists studied two complement components that are important parts of the immune system and are linked to schizophrenia and autoimmune disorders. They studied the link between two protein concentrations -- C3 and C4 -- in over 68,000 newborn babies and the risk of developing six mental disorders later in life.

Psychology Research Schizophrenia
Published

An unexpected link between 2 schizophrenia risk proteins      (via sciencedaily.com)     Original source 

The discovery of a physical interaction between two proteins in brain cells that can be traced in mice to control of movement, anxiety and memory could one day open the door to development of new schizophrenia treatment strategies, researchers say.

Bipolar Disorder Depression Today's Healthcare
Published

Simple blood test can help diagnose bipolar disorder      (via sciencedaily.com)     Original source 

Researchers have developed a new way of improving diagnosis of bipolar disorder that uses a simple blood test to identify biomarkers associated with the condition.

Birth Defects Schizophrenia
Published

New clues to early development of schizophrenia      (via sciencedaily.com)     Original source 

Schizophrenia is a severe neuropsychiatric disease that remains poorly understood and treated. Schizophrenia onset is typically in adolescence or early adulthood, but its underlying causes are thought to involve neurodevelopmental abnormalities. Because human prenatal and postnatal brain tissue is exceedingly difficult to procure and therefore study, researchers have had limited opportunities to identify early disease mechanisms, especially during the critical prenatal period. Now, a pair of studies use new technology to study schizophrenia in models of early human brain development.

Bipolar Disorder Children's Health Depression Mental Health Research Psychology Research
Published

Researchers confirm postpartum depression heritability, home in on treatment mechanism      (via sciencedaily.com)     Original source 

Researchers have conducted a large-scale meta-analyses of genome-wide association studies (GWAS) to investigate the genetic architecture of PPD.

Psychology Research Schizophrenia
Published

Brain connectivity is disrupted in schizophrenia      (via sciencedaily.com)     Original source 

Schizophrenia, a neurodevelopmental disorder that features psychosis among its symptoms, is thought to arise from disorganization in brain connectivity and functional integration. Now, a new study finds differences in functional brain connectivity in people with and without psychosis and schizophrenia that could help researchers understand the neural underpinnings of this disease.

Child Development Psychology Research Schizophrenia
Published

AI language models could help diagnose schizophrenia      (via sciencedaily.com)     Original source 

Scientists have developed new tools, based on AI language models, that can characterize subtle signatures in the speech of patients diagnosed with schizophrenia.

Schizophrenia
Published

Scientists take next big step in understanding genetics of schizophrenia      (via sciencedaily.com)     Original source 

Scientists are figuring out which of the 5,000 variants associated with schizophrenia have an actual causal effect in the development of the condition that affects millions of people worldwide.

Bipolar Disorder Child Development Depression Mental Health Research Psychology Research
Published

Formerly depressed patients continue to focus on negative      (via sciencedaily.com)     Original source 

People who have recovered from a major depressive episode, when compared with individuals who have never experienced one, tend to spend more time processing negative information and less time processing positive information, putting them at risk for a relapse, according to new research.

Birth Defects Schizophrenia
Published

Schizophrenia genetic risk factor impairs mitochondrial function      (via sciencedaily.com)     Original source 

Researcher discovers possible link of mitochondrial function to the development of schizophrenia.

Bipolar Disorder Depression Mental Health Research
Published

Modern antidepressants may reduce risk of relapse for patients with bipolar depression      (via sciencedaily.com)     Original source 

Treatment with modern antidepressants may help prevent patients with bipolar disorder from relapsing into a depressive episode, according to an international clinical trial. The findings challenge current clinical practice guidelines and could change how bipolar depression is managed globally.