Showing 20 articles starting at article 1
Categories: Bipolar Disorder, Irritable Bowel Syndrome
Published Formerly depressed patients continue to focus on negative


People who have recovered from a major depressive episode, when compared with individuals who have never experienced one, tend to spend more time processing negative information and less time processing positive information, putting them at risk for a relapse, according to new research.
Published Modern antidepressants may reduce risk of relapse for patients with bipolar depression



Treatment with modern antidepressants may help prevent patients with bipolar disorder from relapsing into a depressive episode, according to an international clinical trial. The findings challenge current clinical practice guidelines and could change how bipolar depression is managed globally.
Published Fiber discovery could shape better gut health



Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions.
Published Lower bacterial diversity is associated with irritable bowel syndrome



People with irritable bowel syndrome (IBS) have lower bacterial diversity in the intestine than do healthy people, according to a team of investigators. The investigators believe that theirs is the first analysis to find a clear association between IBS and reduced diversity in the microbiota of the gut.
Published Realtime monitoring with a wearable device reveals IBS-related changes


A research group recorded the autonomic nervous system activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology.
Published Treating gut pain via a Nobel prize-winning receptor


Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin.
Published New study reveals differences in diagnosis of psychiatric disorders between geographies


Diagnosing psychiatric disorders is challenging due to the lack of objective tests. Fortunately, genomic studies can reveal genes associated with increased risk of certain disorders. In a recent study, researchers from Japan investigated whether the genetic correlations between major psychiatric disorders differed among European and East Asian populations. They showed differences in how bipolar disorders are diagnosed by psychiatrists in the East and the West, which might affect the results of clinical trials.
Published How gravity may cause irritable bowel syndrome



A new theory suggests irritable bowel syndrome (IBS), the most common gastrointestinal disorder, may be caused by gravity. An expert explains that IBS -- and many other conditions -- could result from the body's inability to manage gravity.
Published Bloating common issue among Americans



Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren't seeking professional care for it, according to a new study.
Published Adverse pregnancy outcomes in women with inactive inflammatory bowel disease


Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a new study shows. If corroborated, the results may eventually affect recommendations for women with ulcerative colitis who tries to conceive.
Published Histamine-producing gut bacteria can trigger chronic abdominal pain



The culprit is what has now been named Klebsiella aerogenes, the McMaster-Queen (MQ) strain, identified in up to 25 per cent of gut microbiota samples from patients with IBS. Researchers examined stool microbiota samples from both Canadian and American patient cohorts.
Published Multiple diagnoses are the norm for mental illness; A new genetic analysis helps explain why



An analysis of 11 major psychiatric disorders offers new insight into why comorbidities are the norm when it comes to mental illness. The study suggests that while there is no single gene or set of genes underlying risk for all of them, subsets of disorders -- including bipolar disorder and schizophrenia; anorexia nervosa and obsessive-compulsive disorder; and major depression and anxiety --s hare a common genetic architecture.
Published Evidence of brain changes in those at risk of bipolar disorder captured with MRI scans


A study that showed changes in the brain in those at risk of developing bipolar disorder raises new hopes about early intervention.
Published Lithium may decrease risk of developing dementia



Researchers have identified a link suggesting that lithium could decrease the risk of developing dementia, which affects nearly one million people in the UK.
Published People with serious mental illness may have increased heart disease risk at younger ages


An analysis of nearly 600,000 adults in the U.S. found people with bipolar disorder, schizophrenia or schizoaffective disorder had up to double the estimated cardiovascular risk levels than those without such illnesses, even at younger ages. The study focused on adults diagnosed with one of those three serious mental illnesses, who were not hospitalized or living in a mental health treatment center and estimated their 10-year and 30-year cardiovascular risk. Earlier identification and management of major cardiovascular risk factors -- including obesity, smoking, diabetes and high blood pressure -- in young adults with a serious mental illness may reduce risk of heart disease and improve outcomes, researchers said.
Published Clues to treatment of schizophrenia and bipolar disorder found in recently evolved region of the ‘dark genome’



Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder.
Published For IBS, specific diets are less important than expected


Many IBS sufferers avoid certain types of food and often exclude gluten. However, a large new study does not show a relationship between high intake of gluten and increased IBS symptoms. The researchers did find that a certain type of carbohydrate called 'fodmaps' can aggravate intestinal problems, however, the overall results indicate that they also have less influence than previously thought.
Published Rates of type 2 diabetes are higher in people with one of various common psychiatric disorders



A new study finds that the prevalence of type 2 diabetes (T2D) is elevated in people with a psychiatric disorder compared with the general population.
Published Abnormal brain changes over time with bipolar disorder



Bipolar disorder (BD) is a debilitating psychiatric disorder characterized by fluctuating periods of depression and mania. Researchers have long suspected that BD may be accompanied by abnormal structural and functional changes in the brain. Small cross-sectional brain imaging studies of people with BD have shown hints at those changes, but the ability to interpret data collected at a single timepoint is limited. Now, a multi-center longitudinal study shows aberrant changes over time in the brains of people with BD. Some changes were specifically associated with more episodes of mania.
Published Adjusting fatty acid intake may help with mood variability in bipolar disorders



Can specific dietary guidelines help people living with bipolar disorders better manage their health? Clinical trial results showed that a diet designed to alter levels of specific fatty acids consumed by participants may help patients have less variability in their mood.