Showing 20 articles starting at article 1
Published How does dopamine regulate both learning and motivation? (via sciencedaily.com) Original source
A new study brings together two schools of thought on the function of the neurotransmitter dopamine: one saying that dopamine provides a learning signal, the other saying that dopamine drives motivation.
Published Further link identified between autoimmunity and schizophrenia (via sciencedaily.com) Original source
Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies. Researchers have now identified autoantibodies that target a 'synaptic adhesion protein' in a subset of patients with schizophrenia. When injected into mice, the autoantibodies caused many schizophrenia-related changes.
Published Vitamin D alters developing neurons in the brain's dopamine circuit (via sciencedaily.com) Original source
Neuroscientists have shown how vitamin D deficiency affects developing neurons in the brain's dopamine circuit, which may lead to the dopamine dysfunction seen in adults with schizophrenia.
Published A special omega-3 fatty acid lipid will change how we look at the developing and aging brain (via sciencedaily.com) Original source
Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.
Published The drug fasudil is found to reverse key symptoms of schizophrenia in mice (via sciencedaily.com) Original source
Researchers used the drug fasudil to restore neurons and improve methamphetamine-induced cognitive dysfunction in a mouse model of schizophrenia.
Published Fiber discovery could shape better gut health (via sciencedaily.com) Original source
Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions.
Published Abnormal 12-hour cyclic gene activity found in schizophrenic brains (via sciencedaily.com) Original source
Researchers present the first evidence of 12-hour cycles of gene activity in the human brain. The study also reveals that some of those 12-hour rhythms are missing or altered in the postmortem brains of patients with schizophrenia.
Published Lower bacterial diversity is associated with irritable bowel syndrome (via sciencedaily.com) Original source
People with irritable bowel syndrome (IBS) have lower bacterial diversity in the intestine than do healthy people, according to a team of investigators. The investigators believe that theirs is the first analysis to find a clear association between IBS and reduced diversity in the microbiota of the gut.
Published Realtime monitoring with a wearable device reveals IBS-related changes (via sciencedaily.com)
A research group recorded the autonomic nervous system activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology.
Published Treating gut pain via a Nobel prize-winning receptor (via sciencedaily.com)
Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin.
Published How gravity may cause irritable bowel syndrome (via sciencedaily.com) Original source
A new theory suggests irritable bowel syndrome (IBS), the most common gastrointestinal disorder, may be caused by gravity. An expert explains that IBS -- and many other conditions -- could result from the body's inability to manage gravity.
Published Scientists link rare genetic phenomenon to neuron function, schizophrenia (via sciencedaily.com) Original source
Using state-of-the-art whole-genome sequencing and machine learning techniques, researchers conducted one of the first and the largest investigations of tandem repeats in schizophrenia, elucidating their contribution to the development of this devastating disease.
Published Bloating common issue among Americans (via sciencedaily.com) Original source
Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren't seeking professional care for it, according to a new study.
Published ADHD medication for amphetamine addiction linked to reduced risk of hospitalization and death, study finds (via sciencedaily.com) Original source
The ADHD medication lisdexamfetamine was associated with the lowest risk of hospitalization and death in people with amphetamine addiction, when medications generally used among persons with substance use disorders were compared, according to a new study.
Published Adverse pregnancy outcomes in women with inactive inflammatory bowel disease (via sciencedaily.com)
Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a new study shows. If corroborated, the results may eventually affect recommendations for women with ulcerative colitis who tries to conceive.
Published Inflammation amplifies the effect of genetic risk variants for schizophrenia (via sciencedaily.com) Original source
Schizophrenia patients have fewer connections between nerve cells. This is believed to be caused by genetic risk variants leading to an excessive elimination of nerve cell connections by the immune cells of the brain. Researchers now report that the levels of protein from the relevant risk gene are elevated in first-episode patients and that inflammation further increases the expression of the risk gene.
Published Schizophrenia may increase dementia risk by 2.5 times (via sciencedaily.com) Original source
People with psychotic disorders such as schizophrenia are 2.5 times more likely than those without a psychotic disorder to eventually develop dementia, according to a new review.
Published Histamine-producing gut bacteria can trigger chronic abdominal pain (via sciencedaily.com) Original source
The culprit is what has now been named Klebsiella aerogenes, the McMaster-Queen (MQ) strain, identified in up to 25 per cent of gut microbiota samples from patients with IBS. Researchers examined stool microbiota samples from both Canadian and American patient cohorts.
Published Neuronal cell type for controlling the flow of information in the brain (via sciencedaily.com)
Researchers have identified specific cells that regulate the transmission of information between brain areas. This discovery forms the basis for the development of new treatment options for neuropsychiatric disorders which are characterized by impaired coordination of information flow in the brain.
Published In Krabbe disease, neurons may bring about their own destruction (via sciencedaily.com) Original source
The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study. The discovery represents a new mechanism of action for the mutant gene, presenting a more accurate picture of the disease process that may help in the development of therapies.