Showing 20 articles starting at article 1
Published Blood clotting risk quickly drops after stopping hormonal contraceptives (via sciencedaily.com) Original source
Using birth control pills and other hormone-based contraceptives is known to elevate the risk of blood clots, but a new study suggests that this risk largely goes away within two to four weeks after one stops using these contraceptives. The findings can help patients and doctors weigh the benefits and risks of hormonal contraceptives and guide when to stop using them ahead of events that could further increase the risk of dangerous clots, such as major surgery, prolonged periods of immobility, or when tapering anticoagulant medications after a blood clot.
Published Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence (via sciencedaily.com) Original source
Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.
Published Risk of serious infection even in low-active IBD (via sciencedaily.com) Original source
Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.
Published Genetics links endometriosis and IBS (via sciencedaily.com) Original source
Researchers have found a significant relationship between the risks for endometriosis and common gastrointestinal disorders such as IBS, peptic ulcer disease (PUD) and gastro-oesophageal reflux disease (GORD). Sufferers can find it difficult to distinguish the source of their pain leading to confusion or misdiagnosis and years of delay in treatment during which time the endometriosis can progress to more severe disease -- endometriosis should be considered as a possible cause if a woman presents to her GP with abdominal pain and gastrointestinal symptoms.
Published Amitriptyline helps relieve IBS symptoms (via sciencedaily.com) Original source
Amitriptyline can improve symptoms of irritable bowel syndrome in patients seen in GP surgeries, new research has found. The cheap and widely available prescription drug, which is commonly used at low doses for a range of health concerns, has been found to improve irritable bowel syndrome (IBS) symptoms too, according to the results of the ATLANTIS trial. The results showed that patients taking amitriptyline were almost twice as likely to report an overall improvement in symptoms as those taking a placebo.
Published Fungal infection in the brain produces changes like those seen in Alzheimer's disease (via sciencedaily.com) Original source
Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.
Published Brain is 'rewired' during pregnancy to prepare for motherhood (via sciencedaily.com) Original source
Researchers have shown that pregnancy hormones ‘rewire’ the brain to prepare mice for motherhood. The findings show that both estrogen and progesterone act on a small population of neurons in the brain to switch on parental behavior even before offspring arrive. These adaptations resulted in stronger and more selective responses to pups.
Published New device rapidly controls postpartum hemorrhage (via sciencedaily.com) Original source
A study led by obstetricians has shown that a new device can rapidly control postpartum hemorrhage, a major cause of severe maternal morbidity and death, in a wide range of patients.
Published Natural compound found in plants inhibits deadly fungi (via sciencedaily.com) Original source
A new study finds that a natural compound found in many plants inhibits the growth of drug-resistant Candida fungi -- including its most virulent species, Candida auris, an emerging global health threat.
Published A gut hormone for controlling appetite doubles as an immune regulator for the fungal microbiome (via sciencedaily.com) Original source
Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research.
Published Deadly fungus beaten with new type of treatment (via sciencedaily.com) Original source
Researchers have discovered a new way to attack fungal infections. The key is to block fungi from being able to make fatty acids, the major component of fats. Resistance to anti-fungal drugs is increasing and this new approach will be particularly useful because it works in a new way and affects a broad range of fungal species.
Published New study using human fibroid cells supports use of green tea compound as treatment for uterine fibroids (via sciencedaily.com) Original source
In a pre-clinical, proof-of-concept study, researchers found that epigallocatechin gallate (EGCG), a green tea compound with powerful antioxidant properties, could be promising for both treating and preventing uterine fibroids. Results of the study add to growing evidence that EGCG may reduce fibroid cell growth. The study was specifically designed to identify the biochemical mechanisms responsible for EGCG action in fibroid cells.
Published Elimination of type of bacteria suggests treatment for endometriosis (via sciencedaily.com) Original source
A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.
Published Dynamic expression of brain serotonin receptors across the menstrual cycle provides clues about premenstrual dysphoric disorder (via sciencedaily.com) Original source
A new study explores the interplay between the serotonin system and estradiol in the brain, showing that the central nervous system in patients with premenstrual dysphoric disorder (PMDD) seems to increase serotonin transporter density from the periovulatory phase (when estradiol levels are high) to premenstrual cycle phase (when both estradiol and progesterone are decreasing). The findings have the potential to advance the clinical treatment of PMDD.
Published Migraines during menstruation: Low estrogen levels paired with higher CGRP levels may jump start migraine (via sciencedaily.com) Original source
As estrogen levels fluctuate, a new study has found for female participants with migraine, their levels of the protein calcitonin gene-related peptide (CGRP) that plays a key role in starting the migraine process also fluctuate.
Published Fiber discovery could shape better gut health (via sciencedaily.com) Original source
Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions.
Published Does lifetime exposure to estrogen affect risk of stroke? (via sciencedaily.com)
People with a higher cumulative estrogen exposure throughout their life may have a lower risk of stroke, according to a new study. The lower risk was found for both ischemic stroke and intracerebral hemorrhage.
Published Lower bacterial diversity is associated with irritable bowel syndrome (via sciencedaily.com) Original source
People with irritable bowel syndrome (IBS) have lower bacterial diversity in the intestine than do healthy people, according to a team of investigators. The investigators believe that theirs is the first analysis to find a clear association between IBS and reduced diversity in the microbiota of the gut.
Published Realtime monitoring with a wearable device reveals IBS-related changes (via sciencedaily.com)
A research group recorded the autonomic nervous system activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology.
Published Treating gut pain via a Nobel prize-winning receptor (via sciencedaily.com)
Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin.