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Categories: Irritable Bowel Syndrome

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Irritable Bowel Syndrome
Published

Fecal microbiota transplant recommended for the majority of recurrent C. diff patients      (via sciencedaily.com)     Original source 

In the first comprehensive evidence-based guideline on the use of fecal microbiota-based therapies for gastrointestinal disease, the American Gastroenterological Association recommends fecal microbiota transplant (FMT) for most patients with recurrent Clostridioides difficile (C. diff) infection. FMT therapies are not recommended as a treatment for inflammatory bowel diseases (IBD) or irritable bowel syndrome (IBS).

Chronic Illness Crohn's Disease Irritable Bowel Syndrome
Published

Risk of serious infection even in low-active IBD      (via sciencedaily.com)     Original source 

Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.

Chronic Illness Irritable Bowel Syndrome
Published

Genetics links endometriosis and IBS      (via sciencedaily.com)     Original source 

Researchers have found a significant relationship between the risks for endometriosis and common gastrointestinal disorders such as IBS, peptic ulcer disease (PUD) and gastro-oesophageal reflux disease (GORD). Sufferers can find it difficult to distinguish the source of their pain leading to confusion or misdiagnosis and years of delay in treatment during which time the endometriosis can progress to more severe disease -- endometriosis should be considered as a possible cause if a woman presents to her GP with abdominal pain and gastrointestinal symptoms.

Irritable Bowel Syndrome Today's Healthcare
Published

Amitriptyline helps relieve IBS symptoms      (via sciencedaily.com)     Original source 

Amitriptyline can improve symptoms of irritable bowel syndrome in patients seen in GP surgeries, new research has found.  The cheap and widely available prescription drug, which is commonly used at low doses for a range of health concerns, has been found to improve irritable bowel syndrome (IBS) symptoms too, according to the results of the ATLANTIS trial. The results showed that patients taking amitriptyline were almost twice as likely to report an overall improvement in symptoms as those taking a placebo.   

Irritable Bowel Syndrome Nutrition
Published

Fiber discovery could shape better gut health      (via sciencedaily.com)     Original source 

Changing the structure of a dietary fiber commonly found in a range of food products has been found to promote healthy gut bacteria and reduce gas formation, a finding that could help people with intolerances to fiber and irritable bowel conditions.

Irritable Bowel Syndrome
Published

Lower bacterial diversity is associated with irritable bowel syndrome      (via sciencedaily.com)     Original source 

People with irritable bowel syndrome (IBS) have lower bacterial diversity in the intestine than do healthy people, according to a team of investigators. The investigators believe that theirs is the first analysis to find a clear association between IBS and reduced diversity in the microbiota of the gut.

Irritable Bowel Syndrome
Published

Realtime monitoring with a wearable device reveals IBS-related changes      (via sciencedaily.com) 

A research group recorded the autonomic nervous system activity in patients with irritable bowel syndrome (IBS) and healthy subjects using a wearable device and a proprietary smartphone application to record daily life events such as defecation and sleep. As a result, they found that sympathetic nervous system activity was activated in IBS patients from 2 minutes before defecation and continued until 9 minutes after defecation. Further research is expected to improve the quality of life of IBS patients and elucidate the pathophysiology.

Chronic Illness Irritable Bowel Syndrome Neuropathy
Published

Treating gut pain via a Nobel prize-winning receptor      (via sciencedaily.com) 

Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome. A team examining the colon identified the presence of Piezo2, the subject of the 2021 Nobel Prize in Physiology or Medicine, now known to be responsible for sensing light touch on our skin.

Irritable Bowel Syndrome
Published

How gravity may cause irritable bowel syndrome      (via sciencedaily.com)     Original source 

A new theory suggests irritable bowel syndrome (IBS), the most common gastrointestinal disorder, may be caused by gravity. An expert explains that IBS -- and many other conditions -- could result from the body's inability to manage gravity.

Irritable Bowel Syndrome
Published

Bloating common issue among Americans      (via sciencedaily.com)     Original source 

Nearly 1 in 7 Americans experience bloating on a weekly basis, and most aren't seeking professional care for it, according to a new study.

Birth Defects Crohn's Disease Infant's Health Irritable Bowel Syndrome Pregnancy and Childbirth
Published

Adverse pregnancy outcomes in women with inactive inflammatory bowel disease      (via sciencedaily.com) 

Inflammatory bowel disease is a risk factor for giving birth preterm even when in apparent disease remission, a new study shows. If corroborated, the results may eventually affect recommendations for women with ulcerative colitis who tries to conceive.

Irritable Bowel Syndrome
Published

Histamine-producing gut bacteria can trigger chronic abdominal pain      (via sciencedaily.com)     Original source 

The culprit is what has now been named Klebsiella aerogenes, the McMaster-Queen (MQ) strain, identified in up to 25 per cent of gut microbiota samples from patients with IBS. Researchers examined stool microbiota samples from both Canadian and American patient cohorts.

Irritable Bowel Syndrome
Published

For IBS, specific diets are less important than expected      (via sciencedaily.com) 

Many IBS sufferers avoid certain types of food and often exclude gluten. However, a large new study does not show a relationship between high intake of gluten and increased IBS symptoms. The researchers did find that a certain type of carbohydrate called 'fodmaps' can aggravate intestinal problems, however, the overall results indicate that they also have less influence than previously thought.

Irritable Bowel Syndrome
Published

Seeking a treatment for IBS pain in tarantula venom      (via sciencedaily.com) 

For patients who have irritable bowel syndrome (IBS), the condition is literally a pain in the gut. Chronic -- or long-term -- abdominal pain is common, and there are currently no effective treatment options for this debilitating symptom. In a new study, researchers identify a new potential source of relief: a molecule derived from spider venom. In experiments with mice, they found that one dose could stop symptoms associated with IBS pain.

Irritable Bowel Syndrome
Published

Open-label placebo works as well as double-blind placebo in irritable bowel syndrome      (via sciencedaily.com)     Original source 

In a randomized clinical trial, researchers found participants with moderate to severe irritable bowel syndrome (IBS) who were knowingly treated with a pharmacologically inactive pill -- referred to as an honest or open-label placebo -- reported clinically meaningful improvements in their IBS symptoms.

Irritable Bowel Syndrome
Published

Scientists reveal mechanism that causes irritable bowel syndrome      (via sciencedaily.com)     Original source 

Researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study was carried out in mice and humans.

Irritable Bowel Syndrome
Published

New treatment in development for irritable bowel syndrome with constipation      (via sciencedaily.com)     Original source 

Preclinical studies find that an innovative bilayered capsule can overcome current challenges for delivering drugs to the colon. The findings suggest a new solution for relieving abdominal pain associated with IBS-C.

Irritable Bowel Syndrome
Published

Specific bacterium in the gut linked to irritable bowel syndrome (IBS)      (via sciencedaily.com) 

Researchers have detected a connection between Brachyspira, a genus of bacteria in the intestines, and IBS -- especially the form that causes diarrhea. Although the discovery needs confirmation in larger studies, there is hope that it might lead to new remedies for many people with irritable bowel syndrome.

Irritable Bowel Syndrome
Published

Review finds almost 20 percent of COVID-19 patients only show gastrointestinal symptoms      (via sciencedaily.com)     Original source 

Almost one in five patients with COVID-19 may only show gastrointestinal symptoms, according to a review of academic studies. The findings of the review suggest abdominal radiologists need to remain vigilant during the pandemic while imaging patients.

Irritable Bowel Syndrome
Published

Giant spider provides promise of pain relief for irritable bowel syndrome      (via sciencedaily.com) 

Molecules from the venom of one of the world's largest spiders could help researchers tailor pain blockers for people with irritable bowel syndrome (IBS).