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Categories: Gynecology, Schizophrenia

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Schizophrenia
Published

Student links worm behavior to brain disease      (via sciencedaily.com)     Original source 

An undergraduate student turns her honor's thesis into a peer-reviewed publication on schizophrenia research.

Schizophrenia
Published

Understaffed nursing homes in disadvantaged neighborhoods more likely to overuse antipsychotics      (via sciencedaily.com)     Original source 

Nursing homes in disadvantaged communities are more likely to overmedicate residents with antipsychotics, especially homes that are understaffed, according to a new study.

Birth Defects Children's Health Psychology Research Schizophrenia
Published

Two key brain systems are central to psychosis      (via sciencedaily.com)     Original source 

When the brain has trouble filtering incoming information and predicting what's likely to happen, psychosis can result, research shows.

Healthy Aging Psychology Research Schizophrenia
Published

Reverse effects of trauma? Older brain cells linger unexpectedly before their death      (via sciencedaily.com)     Original source 

Researchers report that mature oligodendrocytes -- the central nervous system cells critical for brain function -- cling to life following a fatal trauma for much, much longer than scientists knew. The findings suggest a new pathway for efforts to reverse or prevent the damage that aging and diseases such as multiple sclerosis cause to these important cells.

Healthy Aging Schizophrenia
Published

Schizophrenia and aging may share a common biological basis      (via sciencedaily.com)     Original source 

Researchers have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and from older adults. These changes suggest a common biological basis for the cognitive impairment often seen in people with schizophrenia and in the elderly.

Children's Health Mental Health Research Psychology Research Schizophrenia
Published

Bullied teens' brains show chemical change associated with psychosis      (via sciencedaily.com)     Original source 

Researchers have found that adolescents being bullied by their peers are at greater risk of the early stages of psychotic episodes and in turn experience lower levels of a key neurotransmitter in a part of the brain involved in regulating emotions. The finding suggests that this neurotransmitter may be a potential target for pharmaceutical interventions aimed at reducing the risk of psychotic disorders.

Healthy Aging Neuropathy Psychology Research Schizophrenia
Published

Firing nerve fibers in the brain are supplied with energy on demand      (via sciencedaily.com)     Original source 

To rapidly transmit electrical signals in the brain, the long nerve fibers are insulated by specialized cells called oligodendrocytes. These cells also respond to the electrical signals of active nerve fibers and provide them with energy on demand, as researchers have discovered. If this process, regulated by potassium, is disabled in mice, the nerve fibers are severely damaged as the animals age -- resembling the defects of neurodegenerative diseases.

Birth Defects Gynecology Infant's Health Pregnancy and Childbirth
Published

Provides new explanation for why placenta may not properly separate at birth, putting mother and newborn at risk      (via sciencedaily.com)     Original source 

A new study may change the way clinicians and scientists understand, diagnose and treat placenta accreta spectrum disorder, a serious condition in which the placenta fails to separate from the uterus at birth, jeopardizing the life and health of both mother and baby.

Schizophrenia Today's Healthcare
Published

Vigilant monitoring is needed to manage cardiac risks in patients using antipsychotics, doctors say      (via sciencedaily.com)     Original source 

The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study. Caution is advised to manage cardiac risks in patients prescribed these medications, the authors of the study and an accompanying editorial say.

Gynecology
Published

Candida evolution disclosed: New insights into fungal infections      (via sciencedaily.com)     Original source 

Identification of genes under recent selection provides insights into the molecular mechanisms of human-related adaptation in Candida pathogens. The study reveals both known and novel genetic variants associated with drug resistance, offering potential targets for improved antifungal therapies.

Chronic Illness Psychology Research Schizophrenia
Published

Study reveals function of little-understood synapse in the brain      (via sciencedaily.com)     Original source 

New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma. Neuroscientists focused on the synapse connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells. OPCs can differentiate into oligodendrocytes, which produce a sheath around nerves known as myelin. Myelin is the protective sheath covering each nerve cell's axon -- the threadlike portion of a cell that transmits electrical signals between cells.

Schizophrenia Today's Healthcare
Published

Clinical predictive models created by AI are accurate but study-specific, researchers find      (via sciencedaily.com)     Original source 

Scientists were able to show that statistical models created by artificial intelligence (AI) predict very accurately whether a medication responds in people with schizophrenia. However, the models are highly context-dependent and cannot be generalized.

Schizophrenia Today's Healthcare
Published

Quest for personalized medicine hits a snag      (via sciencedaily.com)     Original source 

The quest for personalized medicine, a medical approach in which practitioners use a patient's unique genetic profile to tailor individual treatment, has emerged as a critical goal in the health care sector. But a new study shows that the mathematical models currently available to predict treatments have limited effectiveness.

Fertility Gynecology Menopause Women's Health - General
Published

How do painful fibroids grow?      (via sciencedaily.com)     Original source 

Insights into how uterine tumors grow could give hope to millions of women who deal with painful fibroids.

Child Development Mental Health Research Schizophrenia
Published

Unravelling the association between neonatal proteins and adult health      (via sciencedaily.com)     Original source 

Scientists studied two complement components that are important parts of the immune system and are linked to schizophrenia and autoimmune disorders. They studied the link between two protein concentrations -- C3 and C4 -- in over 68,000 newborn babies and the risk of developing six mental disorders later in life.

Fertility Gynecology Infant's Health Pregnancy and Childbirth
Published

Having a C-section is related to difficulties with conceiving      (via sciencedaily.com)     Original source 

Women who delivered their previous pregnancy by C-section spent a longer time trying to conceive their next pregnancy. Additionally, women who spent a longer time trying to conceive their current pregnancy were more likely to deliver by C-section. The authors concluded that differences in time spent trying to conceive are unlikely to be due to the surgical procedure itself.

Birth Control Gynecology Pregnancy and Childbirth Today's Healthcare
Published

Blood clotting risk quickly drops after stopping hormonal contraceptives      (via sciencedaily.com)     Original source 

Using birth control pills and other hormone-based contraceptives is known to elevate the risk of blood clots, but a new study suggests that this risk largely goes away within two to four weeks after one stops using these contraceptives. The findings can help patients and doctors weigh the benefits and risks of hormonal contraceptives and guide when to stop using them ahead of events that could further increase the risk of dangerous clots, such as major surgery, prolonged periods of immobility, or when tapering anticoagulant medications after a blood clot.

Gynecology
Published

Visualizing fungal infections deep in living host tissue reveals proline metabolism facilitates virulence      (via sciencedaily.com)     Original source 

Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.

Psychology Research Schizophrenia
Published

An unexpected link between 2 schizophrenia risk proteins      (via sciencedaily.com)     Original source 

The discovery of a physical interaction between two proteins in brain cells that can be traced in mice to control of movement, anxiety and memory could one day open the door to development of new schizophrenia treatment strategies, researchers say.