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Categories: Neuropathy, Schizophrenia

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Birth Defects Children's Health Psychology Research Schizophrenia
Published

Two key brain systems are central to psychosis      (via sciencedaily.com)     Original source 

When the brain has trouble filtering incoming information and predicting what's likely to happen, psychosis can result, research shows.

Healthy Aging Psychology Research Schizophrenia
Published

Reverse effects of trauma? Older brain cells linger unexpectedly before their death      (via sciencedaily.com)     Original source 

Researchers report that mature oligodendrocytes -- the central nervous system cells critical for brain function -- cling to life following a fatal trauma for much, much longer than scientists knew. The findings suggest a new pathway for efforts to reverse or prevent the damage that aging and diseases such as multiple sclerosis cause to these important cells.

Chronic Illness Fitness Neuropathy Today's Healthcare
Published

Did you know that physical activity can protect you from chronic pain?      (via sciencedaily.com)     Original source 

Reserachers found that people who were more active in their free time had a lower chance of having various types of chronic pain 7-8 years later. For example, being just a little more active, such as going from light to moderate activity, was associated with a 5% lower risk of reporting some form of chronic pain later. For severe chronic pain in several places in the body, higher activity was associated with a 16% reduced risk. The researchers found that the ability to tolerate pain played a role in this apparent protective effect. That explains why being active could lower the risk of having severe chronic pain, whether or not it was widespread throughout the body.

Diabetes Neuropathy Skin Care Today's Healthcare
Published

Discovery has potential to solve the billion-dollar global cost of poorly managed wound healing      (via sciencedaily.com)     Original source 

Scientists have uncovered a key step in the wound healing process that becomes disabled in diseases like diabetes and aging, contributing to a global healthcare cost of managing poorly healing wounds exceeding $250 billion a year. Importantly, the research reveals a molecule involved in the healing of tissues that -- when injected into animal models -- leads to a drastic acceleration of wound closure, up to 2.5 times faster, and 1.6 times more muscle regeneration.

Healthy Aging Schizophrenia
Published

Schizophrenia and aging may share a common biological basis      (via sciencedaily.com)     Original source 

Researchers have uncovered a strikingly similar suite of changes in gene activity in brain tissue from people with schizophrenia and from older adults. These changes suggest a common biological basis for the cognitive impairment often seen in people with schizophrenia and in the elderly.

Healthy Aging Neuropathy
Published

An overgrowth of nerve cells appears to cause lingering symptoms after recurrent UTIs      (via sciencedaily.com)     Original source 

A perplexing problem for people with recurring urinary tract infections (UTIs) is persistent pain, even after antibiotics have successfully cleared the bacteria. Now researchers have identified the likely cause -- an overgrowth of nerve cells in the bladder.

Children's Health Mental Health Research Psychology Research Schizophrenia
Published

Bullied teens' brains show chemical change associated with psychosis      (via sciencedaily.com)     Original source 

Researchers have found that adolescents being bullied by their peers are at greater risk of the early stages of psychotic episodes and in turn experience lower levels of a key neurotransmitter in a part of the brain involved in regulating emotions. The finding suggests that this neurotransmitter may be a potential target for pharmaceutical interventions aimed at reducing the risk of psychotic disorders.

Chronic Illness Diabetes Neuropathy
Published

Researchers uncover potential non-opioid treatment for chronic pain      (via sciencedaily.com)     Original source 

A new approach to treating neuropathic pain is making a key step forward. Neuropathic pain is among the most difficult types of pain to alleviate and current treatments are often ineffective. Researchers have identified a potential non-opioid treatment.

Healthy Aging Neuropathy Psychology Research Schizophrenia
Published

Firing nerve fibers in the brain are supplied with energy on demand      (via sciencedaily.com)     Original source 

To rapidly transmit electrical signals in the brain, the long nerve fibers are insulated by specialized cells called oligodendrocytes. These cells also respond to the electrical signals of active nerve fibers and provide them with energy on demand, as researchers have discovered. If this process, regulated by potassium, is disabled in mice, the nerve fibers are severely damaged as the animals age -- resembling the defects of neurodegenerative diseases.

Chronic Illness Neuropathy Today's Healthcare
Published

Good and bad news for people with low back pain      (via sciencedaily.com)     Original source 

Low back pain is a major cause of disability around the globe, with more than 570 million people affected. New research shows that many people with persistent low back pain (more than 12 weeks) continue to have moderate-to-high levels of pain and disability.

Neuropathy Today's Healthcare
Published

Clarifying the cause of Guillain-Barré Syndrome      (via sciencedaily.com)     Original source 

Guillain-?Barr Syndrome is a rare condition in which a person's immune system attacks the peripheral nerves. People affected suffer from muscle weakness and paralysis. A research team led by ETH Zurich has now clarified the mechanism of this autoimmune disease.

Schizophrenia Today's Healthcare
Published

Vigilant monitoring is needed to manage cardiac risks in patients using antipsychotics, doctors say      (via sciencedaily.com)     Original source 

The use of the antipsychotic drugs quetiapine and haloperidol is associated with an increased risk of ventricular arrhythmias and sudden cardiac death (SCD) caused by drug-induced QT prolongation, reports a new study. Caution is advised to manage cardiac risks in patients prescribed these medications, the authors of the study and an accompanying editorial say.

Chronic Illness Psychology Research Schizophrenia
Published

Study reveals function of little-understood synapse in the brain      (via sciencedaily.com)     Original source 

New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple sclerosis to Alzheimer's disease, to a type of brain cancer known as glioma. Neuroscientists focused on the synapse connecting neurons to a non-neuronal cell, known as oligodendrocyte precursor cells. OPCs can differentiate into oligodendrocytes, which produce a sheath around nerves known as myelin. Myelin is the protective sheath covering each nerve cell's axon -- the threadlike portion of a cell that transmits electrical signals between cells.

Schizophrenia Today's Healthcare
Published

Clinical predictive models created by AI are accurate but study-specific, researchers find      (via sciencedaily.com)     Original source 

Scientists were able to show that statistical models created by artificial intelligence (AI) predict very accurately whether a medication responds in people with schizophrenia. However, the models are highly context-dependent and cannot be generalized.

Schizophrenia Today's Healthcare
Published

Quest for personalized medicine hits a snag      (via sciencedaily.com)     Original source 

The quest for personalized medicine, a medical approach in which practitioners use a patient's unique genetic profile to tailor individual treatment, has emerged as a critical goal in the health care sector. But a new study shows that the mathematical models currently available to predict treatments have limited effectiveness.

Children's Health Healthy Aging Neuropathy Psychology Research
Published

RSV shown to infect nerve cells, cause inflammation and damage      (via sciencedaily.com)     Original source 

RSV, a common infection in children and the elderly thought to only infect the respiratory tract, can also infect nerve cells and cause nerve damage, according to a new study. The findings could have major implications about whether RSV could be connected to neurological or developmental disorders.

Chronic Illness Fitness Neuropathy Today's Healthcare
Published

Different pain types in multiple sclerosis can cause difficulty staying active      (via sciencedaily.com)     Original source 

Chronic pain can present in multiple forms for multiple sclerosis patients. Some forms make it harder to stay active than others.

Child Development Mental Health Research Schizophrenia
Published

Unravelling the association between neonatal proteins and adult health      (via sciencedaily.com)     Original source 

Scientists studied two complement components that are important parts of the immune system and are linked to schizophrenia and autoimmune disorders. They studied the link between two protein concentrations -- C3 and C4 -- in over 68,000 newborn babies and the risk of developing six mental disorders later in life.

Neuropathy Psychology Research
Published

Lost brain function restored in mice after stroke      (via sciencedaily.com)     Original source 

Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy.