Showing 20 articles starting at article 1
Published Study shows millions of people live with co-occuring chronic pain and mental health symptoms (via sciencedaily.com)
New research found that nearly 1 in 20 adults in the U.S. experience the co-occurrence of chronic pain and anxiety or depression, resulting in functional limitations in daily life.
Published A promising drug candidate for ALS -- prolongs lifespan and eases symptoms in rats and mice (via sciencedaily.com)
A research group has found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS). Cerebral dopamine neurotrophic factor CDNF prolongs the lifespan of and alleviates disease symptoms in rats and mice in animal studies.
Published Posttraumatic brain activity predicts resilience to PTSD (via sciencedaily.com)
After a traumatic experience, most people recover without incident, but some people -- between 2% and 10% -- develop posttraumatic stress disorder (PTSD), a mental health condition that can cause debilitating symptoms of anxiety due to emotional dysregulation. PTSD symptoms are present in up to 40% of trauma survivors in the acute aftermath of trauma, but full-blown PTSD develops in only a small subset of cases. Early identification of those at risk is critical for both early treatment and possible prevention.
Published Compound derived from hops reduces abundance of gut microbe associated with metabolic syndrome (via sciencedaily.com)
Researchers have shown in a mouse model and lab cultures that a compound derived from hops reduces the abundance of a gut bacterium associated with metabolic syndrome.
Published Cognitive behavioral therapy eases how fibromyalgia pain is experienced by the brain (via sciencedaily.com)
Patients living with fibromyalgia (FM) -- a disease that predominantly affects women and is characterized by chronic pain, fatigue and brain fog -- often find limited treatment options and a scarcity of explanations for their symptoms. Investigators have now found that cognitive behavioral therapy (CBT) can significantly reduce the burden of FM by, in part, reducing pain-catastrophizing, a negative cognitive and emotional response that can intensify pain through feelings of helplessness, rumination and intrusive thoughts. This finding is backed by neuroimaging data, evidencing reduced connectivity between regions of the brain associated with self-awareness, pain and emotional processing.
Published Job strain combined with high efforts and low reward doubled men's heart disease risk (via sciencedaily.com)
Men exposed to stressful working conditions who also felt that they put forth high effort but received low reward had twice the risk of heart disease compared to men who were free of those psychosocial stressors.
Published New blood marker can identify Parkinsonian diseases (via sciencedaily.com)
Is it possible that a single biomarker can detect all types of diseases related to dopamine deficiency in the brain? Yes, that's what a research group is discovering. 'We have observed that an enzyme in cerebrospinal fluid and in blood is a useful marker for identifying all types of Parkinson's-related diseases with high accuracy,' says the study leader.
Published Telecare cuts costs, boosts quality of life for dementia patients (via sciencedaily.com)
A telecare program that improves outcomes for patients with dementia and lightens the load for unpaid caregivers also has the surprising bonus of cutting Medicare costs, according to new research.
Published That smell: New gut microbe produces smelly toxic gas but protects against pathogens (via sciencedaily.com)
Microbiologists have discovered a new intestinal microbe that feeds exclusively on taurine and produces the foul-smelling gas hydrogen sulfide. The researchers have thus provided another building block in the understanding of those microbial processes that have fascinating effects on health. This is also true of Taurinivorans muris: the bacterium shows a protective function against Klebsiella and Salmonella, two important pathogens.
Published Study shows nearly 300% increase in ADHD medication errors (via sciencedaily.com)
Researchers investigated the characteristics and trends of out-of-hospital ADHD medication errors among people younger than 20 years old reported to U.S. poison centers from 2000 through 2021.
Published Guidelines follow advances in ALS gene discovery, ongoing gene therapy trials (via sciencedaily.com)
Researchers have developed an evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.
Published Living in a disadvantaged neighborhood affects food choices, weight gain and the microstructure of the brain (via sciencedaily.com)
A new study finds poor quality of available foods, increased intake of calories from foods high in trans-fatty acids, and environments that do not foster physical activity, all prevalent in disadvantaged neighborhoods, disrupt the flexibility of information processing in the brain that is involved in reward, emotion regulation, and cognition.
Published Older adults with digestive diseases experience higher rates of loneliness, depression (via sciencedaily.com)
A team of gastroenterologists and hepatologists examine psychosocial factors in older Americans with gastrointestinal conditions.
Published ER-positive breast cancer presents differing metabolic signatures in African American, white women (via sciencedaily.com)
New research has found that estrogen receptor-positive breast cancer presents differing metabolic signatures in the blood of African American women and non-Hispanic white women.
Published The human lipidome reveals new indicators of health, disease and aging (via sciencedaily.com)
A new survey of an under-explored aspect of human biology uncovers the many roles of the body's 'greasy molecules.'
Published New insights into the development of Parkinson's disease in the brain (via sciencedaily.com)
Researchers have identified a new pathological mechanism for a familial type of Parkinson's disease caused by a mutation in the CHCHD2 gene. Mutant CHCHD2 protein is mislocalized in cells and leads to alpha-synuclein protein aggregates via interactions with another protein, known as Csnk1e/d. These findings indicate that Csnk1e/d inhibition may slow or halt Parkinson's disease development in patients with CHCHD2 mutations, providing new hope for affected families.
Published Online AI-based test for Parkinson's disease severity shows promising results (via sciencedaily.com)
A new artificial intelligence tool can help people with Parkinson's disease remotely assess the severity of their symptoms within minutes. While expert neurologists performed slightly better than the AI model, the AI model outperformed the primary care physicians with UPDRS certification.
Published New Chagas research unravels decades-long mystery of how the tropical disease progresses (via sciencedaily.com)
New research shows that being infected with multiple strains of the Chagas-inducing parasite may hinder the disease's progression.
Published New insights into melanoma development and therapy (via sciencedaily.com)
Researchers have revealed that the expression of a specific isoform of GREB1 Is4 is induced in malignant melanoma cells by the melanocyte-specific transcription factor, MITF. They revealed that GREB1 Is4 stimulates pyrimidine biosynthesis and promotes cancer cell proliferation. Furthermore, the anti-tumor effect of antisense nucleic acids against GREB1 showed a potential new modality for malignant melanoma.
Published First-in-class targeted microRNA therapy slows cancer tumor growth (via sciencedaily.com)
A new cancer therapy attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division.