Showing 20 articles starting at article 1
Published What can bulls tell us about men? (via sciencedaily.com) Original source
Researchers have found genes in the reproductive organs of bulls that influence fertility. The findings can be transferred to humans, as these genes are also present in men.
Published Blocking an essential nutrient inhibits malaria parasite growth (via sciencedaily.com) Original source
Researchers found that by preventing the malaria parasite from scavenging fatty acids, a type of required nutrient, it could no longer grow.
Published Genetic cause of low birth weight among children conceived after fertility treatment (via sciencedaily.com) Original source
A medical researcher has identified a genetic cause for the increased risk of low birth weight in babies born following assisted reproductive technologies such as IVF.
Published Heart organoids simulate pregestational diabetes-induced congenital heart disease (via sciencedaily.com) Original source
An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. The findings also showed that endoplasmic reticulum (ER) stress and lipid imbalance are critical factors contributing to these disorders, which could be ameliorated with exposure to omega-3s.
Published How ovarian tissue freezing could prevent menopause -- possibly forever (via sciencedaily.com) Original source
A new paradigm around the biological processes of menopause is capturing the attention of scientists. The primary question: can menopause be delayed in healthy women, allowing them to extend their child-bearing years -- and perhaps even forestall some of the health risks and uncomfortable symptoms linked to plummeting estrogen levels?
Published Archaeological evidence of seasonal vitamin D deficiency discovered (via sciencedaily.com) Original source
Rickets ran rife in children following the Industrial Revolution, but new research has found factory work and polluted cities aren't entirely to blame for the period's vitamin D deficiencies.
Published Gene expression atlas captures where ovulation can go awry (via sciencedaily.com) Original source
An interdisciplinary collaboration used a cutting-edge form of RNA tagging to map the gene expression that occurs during follicle maturation and ovulation in mice.
Published Semen microbiome health may impact male fertility (via sciencedaily.com) Original source
A new study finds that a small group of microorganisms may be influencing sperm motility.
Published Third major study finds evidence that daily multivitamin supplements improve memory and slow cognitive aging in older adults (via sciencedaily.com) Original source
Researchers tested the effects of a daily multivitamin on cognitive changes in a study of 573 participants with in-person visits in the COSMOS trial. The researchers also conducted a meta-analysis among over 5,000 non-overlapping participants across the three separate cognition studies within the COSMOS trial. Results showed a statistically significant benefit for cognition among participants taking the multi-vitamin compared to placebo, suggesting that a multi-vitamin could help prevent memory loss and slow cognitive aging among older adults.
Published Surprise discovery: For most animals, sperm quality does not reduce with age (via sciencedaily.com) Original source
In humans, male fertility and sperm fitness decline with age, but scientists have made the surprising discovery that this pattern is not consistent in other animals. The team assessed the results of 379 studies which covered a wide range of animals, including mammals, insects, birds, and fish.
Published Energy-starved breast cancer cells consume their surroundings for fuel (via sciencedaily.com) Original source
Breast cancer cells ingest and consume the matrix surrounding them to overcome starvation, according to a new study. The finding elucidates a previously unknown mechanism of cancer cell survival, and may offer a new target for therapy development.
Published A novel pathway regulating lipid biosynthesis by fatty acids (via sciencedaily.com) Original source
Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published New study reveals high prevalence of anemia with low rates of screening (via sciencedaily.com) Original source
A new study has found high rates of anemia among patients in the Irish health system, while screening for common causes was found to be low.
Published Aging mouse sperm affects MicroRNA, increasing the risk of neurodevelopmental disorders (via sciencedaily.com) Original source
Much is known about the added complication to pregnancy when it comes to the age of the mother, but recent studies show that the age of the father can also heighten the risk of neurodevelopmental disorders. A team of researchers has explored the impacts of paternal aging on microRNAs, the molecules that play a crucial role in regulating gene expression.
Published Infertility: Sperm need a breakthrough for fertilization (via sciencedaily.com) Original source
A new study identifies the defective function of CatSper, an ion channel controlling calcium levels in sperm, as a common cause of seemingly unexplained male infertility. CatSper-deficient human sperm fail to fertilize the egg, because they cannot penetrate its protective vestments. Thus far, this sperm channelopathy has remained undetectable. Scientists have unravelled CatSper's role in infertility using a novel laboratory test that identifies affected men.
Published Preconception stress may affect health of women undergoing fertility treatment (via sciencedaily.com) Original source
Stress during pregnancy is known to influence health outcomes, but a new study suggests that stress levels before pregnancy are also important to evaluate. Investigators analyzed the link between self-reported stress immediately before conception among women seeking fertility care and blood glucose levels, a marker of heart health. The team found that maternal stress during preconception was associated with higher blood glucose levels, especially among women using intrauterine insemination to conceive and women of higher socioeconomic status.
Published Nematode proteins shed light on infertility (via sciencedaily.com) Original source
Biologists developed a method for illuminating the intricate interactions of the synaptonemal complex in the nematode C. elegans. The authors identified a trio of protein segments that guide chromosomal interactions, and pinpointed the location where they interact with each other. Their novel method uses a technique known as genetic suppressor screening, which can serve as a blueprint for research on large cellular assemblies that resist traditional structural analysis.
Published Foundation laid for improved diagnostic imaging of brain tumors (via sciencedaily.com) Original source
Research team draws up criteria for PET-based examinations of malignant brain tumors.
Published Aptamers: lifesavers; ion shields: aptamer guardians (via sciencedaily.com) Original source
Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal and chemical stability as well as ability to inhibit specific enzymes or target proteins through three-dimensional binding. They also hold promise for swift diagnoses of colon cancer and other challenging diseases by targeting elusive biomarkers. Despite their utility, these aptamers are susceptible to easy degradation by multiple enzymes, presenting a significant challenge.
Published Healthy omega-3 fats may slow deadly pulmonary fibrosis (via sciencedaily.com) Original source
Higher levels of omega-3, the healthy fat found in fish and nuts, were associated with better lung function and longer transplant-free survival.