Dietary Supplements and Minerals
Published

Similarities and differences in human and insect vision formation      (via sciencedaily.com)     Original source 

Researchers have discovered profound similarities and surprising differences between humans and insects in the production of the critical light-absorbing molecule of the retina, 11-cis-retinal, also known as the 'visual chromophore.' The findings deepen understanding of how mutations in the RPE65 enzyme cause retinal diseases, especially Leber congenital amaurosis, a devastating childhood blinding disease.

Diet and Weight Loss Dietary Supplements and Minerals Nutrition Obesity
Published

Bridging diet, microbes, and metabolism: Implications for metabolic disorders      (via sciencedaily.com)     Original source 

Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.

Sexual Health
Published

Researchers are using RNA in a new approach to fight HIV      (via sciencedaily.com)     Original source 

A pharmacy associate professor has developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight human immunodeficiency virus (HIV) using gene therapy.

Diet and Weight Loss Dietary Supplements and Minerals Nutrition
Published

Eating too much protein is bad for your arteries, and this amino acid is to blame      (via sciencedaily.com)     Original source 

Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.

Chronic Illness Diet and Weight Loss Dietary Supplements and Minerals Nutrition Vitamin
Published

Link between high levels of niacin -- a common B vitamin -- and heart disease, study suggests      (via sciencedaily.com)     Original source 

Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease. Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies. The researchers also showed in preclinical studies that 4PY directly triggers vascular inflammation which damages blood vessels and can lead to atherosclerosis over time.

Healthy Aging Sexual Health
Published

Double risk of dementia after mouth ulcer virus      (via sciencedaily.com)     Original source 

People who have had the herpes virus at some point in their lives are twice as likely to develop dementia compared to those who have never been infected. A new study confirms previous research on whether herpes can be a possible risk factor for dementia.

Dietary Supplements and Minerals
Published

Blocking an essential nutrient inhibits malaria parasite growth      (via sciencedaily.com)     Original source 

Researchers found that by preventing the malaria parasite from scavenging fatty acids, a type of required nutrient, it could no longer grow.

Chronic Illness Diabetes Dietary Supplements and Minerals Pregnancy and Childbirth
Published

Heart organoids simulate pregestational diabetes-induced congenital heart disease      (via sciencedaily.com)     Original source 

An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. The findings also showed that endoplasmic reticulum (ER) stress and lipid imbalance are critical factors contributing to these disorders, which could be ameliorated with exposure to omega-3s.

Dietary Supplements and Minerals Vitamin
Published

Archaeological evidence of seasonal vitamin D deficiency discovered      (via sciencedaily.com)     Original source 

Rickets ran rife in children following the Industrial Revolution, but new research has found factory work and polluted cities aren't entirely to blame for the period's vitamin D deficiencies.

Dietary Supplements and Minerals Healthy Aging Today's Healthcare
Published

Third major study finds evidence that daily multivitamin supplements improve memory and slow cognitive aging in older adults      (via sciencedaily.com)     Original source 

Researchers tested the effects of a daily multivitamin on cognitive changes in a study of 573 participants with in-person visits in the COSMOS trial. The researchers also conducted a meta-analysis among over 5,000 non-overlapping participants across the three separate cognition studies within the COSMOS trial. Results showed a statistically significant benefit for cognition among participants taking the multi-vitamin compared to placebo, suggesting that a multi-vitamin could help prevent memory loss and slow cognitive aging among older adults.

Dietary Supplements and Minerals
Published

Energy-starved breast cancer cells consume their surroundings for fuel      (via sciencedaily.com)     Original source 

Breast cancer cells ingest and consume the matrix surrounding them to overcome starvation, according to a new study. The finding elucidates a previously unknown mechanism of cancer cell survival, and may offer a new target for therapy development.

Dietary Supplements and Minerals
Published

A novel pathway regulating lipid biosynthesis by fatty acids      (via sciencedaily.com)     Original source 

Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.

Dietary Supplements and Minerals Today's Healthcare Vitamin
Published

New study reveals high prevalence of anemia with low rates of screening      (via sciencedaily.com)     Original source 

A new study has found high rates of anemia among patients in the Irish health system, while screening for common causes was found to be low.

Sexual Health
Published

Genetic variants underlying male bisexual behavior, risk-taking linked to more children, study shows      (via sciencedaily.com)     Original source 

Because same-sex sexual behavior does not result in offspring, evolutionary biologists have long wondered how the genes associated with this behavior have persisted in the human genome, and whether they will remain in the future. A new study suggests that part of the explanation -- specifically for male bisexuals -- has to do with risk-taking behavior.

Dietary Supplements and Minerals Today's Healthcare
Published

Foundation laid for improved diagnostic imaging of brain tumors      (via sciencedaily.com)     Original source 

Research team draws up criteria for PET-based examinations of malignant brain tumors.

Dietary Supplements and Minerals
Published

Aptamers: lifesavers; ion shields: aptamer guardians      (via sciencedaily.com)     Original source 

Aptamers, nucleic acids capable of selectively binding to viruses, proteins, ions, small molecules, and various other targets, are garnering attention in drug development as potential antibody substitutes for their thermal and chemical stability as well as ability to inhibit specific enzymes or target proteins through three-dimensional binding. They also hold promise for swift diagnoses of colon cancer and other challenging diseases by targeting elusive biomarkers. Despite their utility, these aptamers are susceptible to easy degradation by multiple enzymes, presenting a significant challenge.

Chronic Illness Dietary Supplements and Minerals
Published

Healthy omega-3 fats may slow deadly pulmonary fibrosis      (via sciencedaily.com)     Original source 

Higher levels of omega-3, the healthy fat found in fish and nuts, were associated with better lung function and longer transplant-free survival.

Dietary Supplements and Minerals
Published

GPCR structure: Research reveals molecular origins of function for a key drug target      (via sciencedaily.com)     Original source 

Scientists reveal how G protein-coupled receptors, major therapeutic drug targets, decode critical properties of their ligands.

Dietary Supplements and Minerals
Published

The key mechanism to cell growth has been elucidated      (via sciencedaily.com)     Original source 

Researchers have discovered how amino acids activate a key cell, TORC1, which is a master regulator in living organisms that controls whether cells grow or recycle their contents in yeast. Notably, the team found that the amino acid cysteine is sensed by a protein called Pib2 and that the two bind together to trigger TORC1. This is important because faulty TORC1 has been linked to disease such as cancer.

Dietary Supplements and Minerals
Published

One of the keys to healthy sleep and blood sugar has been found      (via sciencedaily.com)     Original source 

Researchers have shown that the rare D-form of the amino acid alanine shows a clear circadian rhythm, and is able to affect the circadian clock and regulate gluconeogenesis, a method of glucose release, in the kidney. D-alanine upregulates genes linked to both gluconeogenesis and the circadian rhythm through the circadian transcriptional network. D-alanine is linked to many metabolic and immunological diseases, and this mechanistic insight could potentially lead to novel therapeutic approaches.