Showing 20 articles starting at article 1
Published Chronic fatigue syndrome: Number of patients is expected to double due to long-term effects of the COVID-19 pandemic (via sciencedaily.com) Original source
The number of ME/CFS patients is expected to rise drastically due to long-term effects of the COVID-19 pandemic. Scientists have now identified possible biomarkers that could improve the diagnosis and treatment of long-lasting and debilitating fatigue.
Published Burnout: Identifying people at risk (via sciencedaily.com) Original source
Researchers have developed a new tool that can help identify the early warning signs of burnout.
Published Helping caregivers help people with dementia eat at home (via sciencedaily.com) Original source
A new study has laid the groundwork for a future intervention designed to help caregivers establish a safe and workable mealtime routine for people with dementia living at home.
Published Double risk of dementia after mouth ulcer virus (via sciencedaily.com) Original source
People who have had the herpes virus at some point in their lives are twice as likely to develop dementia compared to those who have never been infected. A new study confirms previous research on whether herpes can be a possible risk factor for dementia.
Published Exposure to Agent Orange damages brain tissue in ways similar to Alzheimer's disease (via sciencedaily.com) Original source
Agent Orange, an herbicide used during the Vietnam War, is a known toxin with wide-ranging health effects. Even though Agent Orange has not been used for decades, there is increasing interest in its effects on the brain health of aging veterans. A new study reveals the mechanisms by which Agent Orange affects the brain and how those processes can lead to neurodegenerative diseases. The research shows that exposures to Agent Orange herbicidal chemicals damage frontal lobe brain tissue of laboratory rats with molecular and biochemical abnormalities that are similar to those found in early-stage Alzheimer's disease.
Published Clinical trial shows rheumatoid arthritis drug could prevent disease (via sciencedaily.com) Original source
A drug used to treat rheumatoid arthritis could also prevent the disease in individuals deemed to be at risk.
Published Protein modifications key influencers in neurodegenerative diseases (via sciencedaily.com) Original source
Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.
Published Scientists debunk role of 'junk cells' in fight against malaria (via sciencedaily.com) Original source
Researchers have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria. The scientists say ABCs could also be key to developing new treatments for chronic autoimmune conditions such as lupus.
Published Analysis of biological networks helps explain the complexity of multiple sclerosis (via sciencedaily.com) Original source
An international study has used a computational biology tool that, by analyzing a multitude of biological data from multiple sclerosis patients ranging from genetic information to the whole organism, reveals the relationship between elements of different biological scales and improves our knowledge and the diagnosis of the disease.
Published New PET tracer detects inflammatory arthritis before symptoms appear (via sciencedaily.com) Original source
A novel PET imaging technique can noninvasively detect active inflammation in the body before clinical symptoms arise, according to new research. Using a PET tracer that binds to proteins present on activated immune cells, the technique produces images of ongoing inflammation throughout the body, such as rheumatoid arthritis. This makes it easier for physicians to correctly diagnose and treat patients.
Published Heart organoids simulate pregestational diabetes-induced congenital heart disease (via sciencedaily.com) Original source
An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. The findings also showed that endoplasmic reticulum (ER) stress and lipid imbalance are critical factors contributing to these disorders, which could be ameliorated with exposure to omega-3s.
Published Pharmacological inhibitor protects nerve cells in ALS disease (via sciencedaily.com) Original source
A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS). Neurobiologists examined a neuroprotective molecule that belongs to a novel drug class. It is able to inhibit the interactions of certain proteins and has been successfully tested in a mouse model of ALS and in brain organoids of ALS patients.
Published Clues to cancer drug's deadly side effects could make it safer (via sciencedaily.com) Original source
For some leukemia patients, their only treatment option carries a risk of heart failure.
Published Researchers make progress toward developing blood tests for psychiatric and neurological disorders (via sciencedaily.com) Original source
Researchers used genetic material from human blood and lab-grown brain cells say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.
Published Stress influences brain and psyche via immune system (via sciencedaily.com) Original source
Chronic stress affects the immune system and the brain. Researchers now show that a particular enzyme found in cells of the immune system enters the brain under stress. In mice, it causes them to withdraw and avoid social contact. This newly discovered connection between body and mind in stress-related mental illnesses could lead to new treatments for depression.
Published The unexpected long-term consequences of female fertility (via sciencedaily.com) Original source
The constant remodeling of the organs of the female reproductive tract during the reproductive cycle leads to fibrosis and chronic inflammation over the years. Scientists have now uncovered these unexpected long-term consequences of female reproductive function in mice.
Published Discovery may enable an effective long-term lupus treatment (via sciencedaily.com) Original source
Researchers have worked out how to fix a defect that causes lupus, and hope their discovery will offer effective long-term treatment.
Published Males born to obese mothers more likely to suffer health issues as adults (via sciencedaily.com) Original source
Males born to obese women are more likely to be overweight at birth and develop metabolic complications in later life, including liver disease and diabetes.
Published Scientist shows focused ultrasound can reach deep into the brain to relieve pain (via sciencedaily.com) Original source
Scientists have found soundwaves from low-intensity focused ultrasound aimed at a place deep in the brain called the insula can reduce both the perception of pain and other effects of pain, such as heart rate changes.
Published Lighting up Alzheimer's-related proteins to allow for earlier disease detection (via sciencedaily.com) Original source
Many neurodegenerative diseases, including Alzheimer's and Parkinson's, are difficult to diagnose before symptoms begin to appear. However, disease-related biomarkers such as aggregated proteins called amyloids could provide important insight much earlier, if they can be readily detected. Researchers have developed one such method using an array of sensor molecules that can light up amyloids. The tool could help monitor disease progression or distinguish between different amyloid-related conditions.