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Categories: Chronic Illness, Diabetes

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Diabetes Nutrition
Published

Sweet taste receptor affects how glucose is handled metabolically by humans      (via sciencedaily.com)     Original source 

The sweet-taste receptor might be the first stop in a metabolic surveillance system for sugar. The receptor is also expressed in certain intestinal cells, where it may facilitate glucose absorption and assimilation, as part of this system. A team found that stimulation and inhibition of the sweet receptor helps regulate glucose metabolism in humans and may have implications for managing such metabolic disorders as diabetes.

Chronic Illness Healthy Aging
Published

The vicious cycle of protein clumping in Alzheimer's disease and normal aging      (via sciencedaily.com)     Original source 

To date, approaches to treatments for Alzheimer's disease have not addressed the contribution of protein insolubility as a general phenomenon, instead focusing on one or two insoluble proteins. Researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging. Furthermore, the work demonstrated an intervention that could reverse the toxic effects of the aggregates by boosting mitochondrial health.

Chronic Illness
Published

New gene delivery vehicle shows promise for human brain gene therapy      (via sciencedaily.com)     Original source 

In an important step toward more effective gene therapies for brain diseases, researchers have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein. Because the vehicle binds to a well-studied protein in the blood-brain barrier, the scientists say it has a good chance at working in patients.

Chronic Illness
Published

Celiac disease: New findings on the effects of gluten      (via sciencedaily.com)     Original source 

Celiac disease is a chronic autoimmune condition that occurs in around one per cent of the world's population. It is triggered by the consumption of gluten proteins from wheat, barley, rye and some oats. A gluten-free diet protects celiac patients from severe intestinal damage.

Diabetes Nutrition Obesity
Published

Two decades of studies suggest health benefits associated with plant-based diets      (via sciencedaily.com)     Original source 

Vegetarian and vegan diets are generally associated with better status on various medical factors linked to cardiovascular health and cancer risk, as well as lower risk of cardiovascular diseases, cancer, and death, according to a new review of 49 previously published papers.

Chronic Illness Obesity
Published

Fighting fat and inflammation: Scientists develop powerful new compounds      (via sciencedaily.com)     Original source 

Obesity and inflammatory diseases are increasing in prevalence and contribute to the growing burden of lifestyle disorders such as diabetes and hypertension. There is a lack of naturally derived alternatives to tackle these issues. Researchers have synthesized novel amino acid derivatives of menthol and studied its properties. The menthyl esters showed exceptional anti-inflammatory and anti-obesity activities during preclinical studies and can be developed as therapeutic compounds with further research.

Chronic Illness
Published

Drug compounds to combat neurodegenerative diseases      (via sciencedaily.com)     Original source 

Prions are the abnormal, pathogenic agents that are transmissible and are able to induce abnormal folding of specific normal cellular proteins. Prion disease is an umbrella term for a group of fatal and currently untreatable neurodegenerative diseases that not only affect humans, but also wild and captive animals. These diseases include Creutzfeldt-Jakob disease (CJD) in humans, bovine spongiform encephalopathy (BSE, or 'mad cow disease'), and chronic wasting disease (CWD) affecting deer, elk and moose.

Chronic Illness Healthy Aging
Published

Discrimination may accelerate aging      (via sciencedaily.com)     Original source 

Discrimination may speed up the biological processes of aging, according to a new study.

Chronic Illness Diabetes
Published

How night shift work can raise risk of diabetes, obesity      (via sciencedaily.com)     Original source 

Just a few days on a night shift schedule throws off protein rhythms related to blood glucose regulation, energy metabolism and inflammation, processes that can influence the development of chronic metabolic conditions. The finding provides new clues as to why night shift workers are more prone to diabetes, obesity and other metabolic disorders. Though more research is needed, the researchers said the study shows that these disrupted rhythms can be seen in as little as three days, which suggests early intervention to prevent diabetes and obesity is possible. Such intervention could also help lower the risk of heart disease and stroke, which is elevated in night shift workers as well.

Diabetes Neuropathy Today's Healthcare
Published

Neuropathy very common, underdiagnosed      (via sciencedaily.com)     Original source 

Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a new study.

Chronic Illness Psychology Research Today's Healthcare
Published

'Wraparound' implants represent new approach to treating spinal cord injuries      (via sciencedaily.com)     Original source 

A tiny, flexible electronic device that wraps around the spinal cord could represent a new approach to the treatment of spinal injuries, which can cause profound disability and paralysis. A team of engineers, neuroscientists and surgeons developed the devices and used them to record the nerve signals going back and forth between the brain and the spinal cord. Unlike current approaches, the new devices can record 360-degree information, giving a complete picture of spinal cord activity.

Child Development Children's Health Chronic Illness Mental Health Research Parenting
Published

Teens who view their homes as more chaotic than their siblings have poorer mental health in adulthood      (via sciencedaily.com)     Original source 

Adolescents who view their households as more unstructured, disorganized, or hectic than their siblings develop more mental health and behavioral problems in early adulthood, according to new research.

Child Development Children's Health Chronic Illness Depression Mental Health Research Parenting
Published

Children sleep problems associated with psychosis in young adults      (via sciencedaily.com)     Original source 

Children who experience chronic lack of sleep from infancy may be at increased risk of developing psychosis in early adulthood, new research shows.

Chronic Illness Healthy Aging Psychology Research
Published

Damaging impact of heat waves on vital organs      (via sciencedaily.com)     Original source 

Researchers have found evidence of the molecular causes of the damaging impact heat stress causes on the gut, liver and brain in the elderly. These findings point to the potential of developing precise prognostic and therapeutic interventions.

Child Development Children's Health Chronic Illness Depression Mental Health Research Psychology Research
Published

Childhood maltreatment responsible for up to 40 percent of mental health conditions      (via sciencedaily.com)     Original source 

A study has found the widespread impact of child abuse and neglect, with analysis suggesting they cause nearly half of common mental conditions. Researchers say childhood maltreatment should be treated as a public health priority.

Birth Defects Chronic Illness Psychology Research
Published

Gene linked to learning difficulties has direct impact on learning and memory      (via sciencedaily.com)     Original source 

A gene previously linked to intellectual disability has been found to regulate learning and memory in mice.

Diabetes
Published

Biomarker found to help identify cells that can repair damaged blood vessels      (via sciencedaily.com)     Original source 

Researchers have discovered a protein marker to help identify cells able to repopulate in patients with damaged blood vessels. Their findings could lead to new therapies for people with endothelial dysfunction, a type of disorder that contributes to coronary artery disease that may occlude with plaque and lack ability to carry sufficient blood into the heart tissue causing a heart attack.

Chronic Illness
Published

US geographic region results in vastly different anal cancer risk for people with HIV      (via sciencedaily.com)     Original source 

For people with HIV, the risk of anal cancer varies according to their geographic region.

Chronic Illness Diet and Weight Loss Nutrition Obesity Today's Healthcare
Published

Intermittent fasting protects against liver inflammation and liver cancer      (via sciencedaily.com)     Original source 

Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development. The fasting regime reduces the development of liver cancer in mice with pre-existing liver inflammation. The researchers identified two proteins in liver cells that are jointly responsible for the protective effect of fasting. An approved drug can partially mimic this effect.

Diabetes
Published

Decoding the three ancestral components of the Japanese people      (via sciencedaily.com)     Original source 

A research group have used whole-genome sequencing to unravel the complex ancestry of the Japanese population. The analysis supports an earlier study that proposed that the Japanese population originated from admixtures of three ancestral groups, challenging the long-held dual-structure model.