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Categories: Healthy Aging, Vitamin

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Chronic Illness Healthy Aging
Published

The vicious cycle of protein clumping in Alzheimer's disease and normal aging      (via sciencedaily.com)     Original source 

To date, approaches to treatments for Alzheimer's disease have not addressed the contribution of protein insolubility as a general phenomenon, instead focusing on one or two insoluble proteins. Researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging. Furthermore, the work demonstrated an intervention that could reverse the toxic effects of the aggregates by boosting mitochondrial health.

Birth Defects Healthy Aging Psychology Research
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Research sheds light on how proteins linked to Alzheimer's disease influence neuronal growth      (via sciencedaily.com)     Original source 

New research has shed light in the complex interplay between cell proteins, and how they impact on neurons in neurodevelopmental disorders and Alzheimer's disease.

Healthy Aging Psychology Research
Published

Alzheimer's disease without symptoms: How is that possible?      (via sciencedaily.com)     Original source 

Everyone experiences aging in their own way, and factors such as genetics, lifestyle and environment play a role in this process. Some individuals reach the age of 90 or even 100 in good health, without medications or brain disease. But how do these individuals maintain their health as they age?

Healthy Aging
Published

Study links sleep apnea severity during REM stage to verbal memory decline      (via sciencedaily.com)     Original source 

A research team has revealed the link between the frequency of sleep apnea events during the rapid-eye-movement stage and the severity of verbal memory impairment in older adults at risk for Alzheimer's disease. Verbal memory refers to the cognitive ability to retain and recall information presented through spoken words or written text and is particularly vulnerable to Alzheimer's.

Healthy Aging
Published

Genes driving age-related blood cell mutations uncovered      (via sciencedaily.com)     Original source 

New research identifies a larger pool of genes involved in clonal haematopoiesis than previously thought, and their implications for disease and diagnostic tests.

Healthy Aging Psychology Research
Published

Some brain cells age faster and are more prevalent in Alzheimer's      (via sciencedaily.com)     Original source 

Engineers have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer's disease. Additionally, researchers observed male-female-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of 'old' oligodendrocytes to 'old' neurons compared to the male cortex. The discoveries were made possible by a new technique called MUSIC (multinucleic acid interaction mapping in single cells), which allows researchers to peek inside individual brain cells and map out interactions between chromatin--which is the tightly coiled form of DNA -- and RNA.

Healthy Aging
Published

Distinct population of 'troublemaker' platelet cells appear with aging, lead to blood clotting, disease      (via sciencedaily.com)     Original source 

Researchers have discovered a distinct, secondary population of platelets that appears with aging and have hyperreactive behavior and unique molecular properties, which could make them easier to target with medication.

Chronic Illness Healthy Aging
Published

Discrimination may accelerate aging      (via sciencedaily.com)     Original source 

Discrimination may speed up the biological processes of aging, according to a new study.

Diet and Weight Loss Dieting and Weight Control Healthy Aging
Published

How biological aging clocks tick      (via sciencedaily.com)     Original source 

Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth. The precision of these aging clocks suggests that the aging process follows a program. Scientists have now discovered that aging clocks actually measure the increase in stochastic changes in cells.

Healthy Aging Skin Care
Published

Who should receive preventive treatment for TB? Individuals of all ages with positive skin or blood test      (via sciencedaily.com)     Original source 

Researcher found that exposed individuals with confirmed TB infection -- i.e. a positive skin or blood test -- should receive priority treatment in settings with a low prevalence of the disease, regardless of their age. However, in high-burden settings, all exposed individuals should be considered for preventative treatment, even without a confirmed infection. This strategy can help end the tuberculosis epidemic and support global public health efforts to reduce TB mortality by 95 percent by 2035 (from 2015 estimates).

Chronic Illness Healthy Aging Psychology Research
Published

Damaging impact of heat waves on vital organs      (via sciencedaily.com)     Original source 

Researchers have found evidence of the molecular causes of the damaging impact heat stress causes on the gut, liver and brain in the elderly. These findings point to the potential of developing precise prognostic and therapeutic interventions.

Healthy Aging Women's Health - General
Published

Could getting enough sleep help prevent osteoporosis?      (via sciencedaily.com)     Original source 

In people's early- to mid-20s, they reach what is called peak bone mineral density, which is higher for men than it is for women, according to researchers. This peak is one of the main determinants of fracture risk later in life. After reaching this peak, a person's bone density remains roughly stable for a couple of decades. Then, when women enter the menopausal transition, they experience accelerated bone loss. Men also experience bone density decline as they age. Sleep patterns also evolve over time.

Healthy Aging
Published

How E. coli get the power to cause urinary tract infections      (via sciencedaily.com)     Original source 

New research examines how the bacteria Escherichia coli, or E. coli -- responsible for most UTIs -- is able to use host nutrients to reproduce at an extraordinarily rapid pace during infection despite the near sterile environment of fresh urine.

Dietary Supplements and Minerals Nutrition Vitamin
Published

New study challenges one-size-fits-all approach to vitamin D supplementation guidelines      (via sciencedaily.com)     Original source 

A new study sheds light on the complexities of achieving optimal vitamin D status across diverse populations. Despite substantial research on the determinants of vitamin D, levels of vitamin D deficiency remain high. Researchers believe their findings have significant implications for the development of tailored recommendations for vitamin D supplementation.

Healthy Aging Psychology Research
Published

Small molecule shows early-stage promise for repairing myelin sheath damage      (via sciencedaily.com)     Original source 

A breakthrough study appears to overcome difficulties that have long frustrated previous attempts to reverse a form of nerve damage that robs people with MS of motor control and gradually blunts cognitive functions for many people as they age.

Dietary Supplements and Minerals Nutrition Psychology Research Vitamin
Published

Nutrient research reveals pathway for treating brain disorders      (via sciencedaily.com)     Original source 

The team discovered that an essential nutrient called choline is transported into the brain, across the blood-brain barrier, by a protein transporter called FLVCR2. This is discovery will inform future design of drugs for diseases such as Alzheimer's and stroke, mimicking choline so they can be smuggled into the brain.

Healthy Aging
Published

Uncovering the secret of long-lived stem cells      (via sciencedaily.com)     Original source 

Researchers have discovered that the enzyme cyclophilin A, which is produced in large amounts in hematopoietic stem cells, is key for these cells to retain their regenerative potential and avert the effects of aging via an unexpected mechanism.

Chronic Illness Healthy Aging
Published

The aspirin conundrum: Navigating negative results, age, aging dynamics and equity      (via sciencedaily.com)     Original source 

A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers.

Healthy Aging
Published

People with rare longevity mutation may also be protected from cardiovascular disease      (via sciencedaily.com)     Original source 

Patients with growth hormone receptor deficiency, or Laron syndrome, appear to have lower than average risk factors for cardiovascular disease, according to a new study.

Healthy Aging
Published

RNA modification is responsible for the disruption of mitochondrial protein synthesis in Alzheimer's disease      (via sciencedaily.com)     Original source 

A team of researchers has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.