Showing 20 articles starting at article 1
Published Elimination of type of bacteria suggests treatment for endometriosis (via sciencedaily.com) Original source
A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.
Published Fibromyalgia: Pain out of control (via sciencedaily.com) Original source
Feeling like we have a degree of control makes us tolerate pain better. In the case of fibromyalgia, however, this simply doesn't work. A study provides clues as to why.
Published Dynamic expression of brain serotonin receptors across the menstrual cycle provides clues about premenstrual dysphoric disorder (via sciencedaily.com) Original source
A new study explores the interplay between the serotonin system and estradiol in the brain, showing that the central nervous system in patients with premenstrual dysphoric disorder (PMDD) seems to increase serotonin transporter density from the periovulatory phase (when estradiol levels are high) to premenstrual cycle phase (when both estradiol and progesterone are decreasing). The findings have the potential to advance the clinical treatment of PMDD.
Published Migraines during menstruation: Low estrogen levels paired with higher CGRP levels may jump start migraine (via sciencedaily.com) Original source
As estrogen levels fluctuate, a new study has found for female participants with migraine, their levels of the protein calcitonin gene-related peptide (CGRP) that plays a key role in starting the migraine process also fluctuate.
Published Antidepressants used for chronic pain on the rise, but are they effective? (via sciencedaily.com) Original source
New research has found some antidepressants may be effective in treating certain chronic pain conditions, but others lack convincing evidence on their effectiveness.
Published Does lifetime exposure to estrogen affect risk of stroke? (via sciencedaily.com)
People with a higher cumulative estrogen exposure throughout their life may have a lower risk of stroke, according to a new study. The lower risk was found for both ischemic stroke and intracerebral hemorrhage.
Published Birth choices after previous cesarean and risk of pelvic floor surgery (via sciencedaily.com) Original source
Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who have had a previous cesarean section when planning how to give birth in their next pregnancy.
Published Fungal association with tumors may predict worse outcomes (via sciencedaily.com)
The presence of some fungal species in tumors predicts -- and may even help drive -- worse cancer outcomes, according to a new study.
Published Advanced imaging sheds light on immune escape of shape-shifting fungus (via sciencedaily.com) Original source
Fungal pathogens have a major global impact upon human health -- they are often difficult to diagnose and treat, and there is an urgent need for better diagnostics and more effective antifungal treatments. Using newly developed imaging technologies, researchers have now revealed how Candida albicans, a common fungus, evades immune responses. According to the researchers this involves an 'alien-like' shape shifting that allows the fungus to break out of immune cells.
Published Data on cancer risk from hormone therapy 'reassuring,' menopause experts say (via sciencedaily.com) Original source
A new scientific paper and other recent evidence offer important reassurances about the risk of breast cancer from hormone therapy to treat menopause symptoms, two menopause experts say.
Published Curbing Candida: The cells that keep fungal infections at bay (via sciencedaily.com) Original source
Researchers have uncovered a previously unknown defense mechanism employed by the immune system in fighting Candida infections.
Published Women burn fat even after menopause (via sciencedaily.com) Original source
The estrogen deficiency following menopause is thought to impair women's ability to use fat as an energy source. A study shows that menopausal state or blood estrogen levels do not clearly determine the rate middle-aged women are able to use fat at rest or during exercise. Higher fat utilization did not indicate better glucose tolerance.
Published Uterine transplantation is efficacious and safe, study suggests (via sciencedaily.com)
Transplanting a uterus is an effective, safe method to remedy infertility when a functioning uterus is lacking. This is the conclusion from a thorough study of uterine transplantation.
Published Progress toward personalized prevention of preterm birth: When progesterone works and when it does not (via sciencedaily.com) Original source
The most effective intervention to prevent preterm birth is the administration of a natural hormone, progesterone, in patients at risk for premature delivery. Two categories of patients have been eligible for this treatment: those with a short cervix and those with a previous preterm birth. But new research indicates that progesterone is not effective in reducing the rate of preterm birth in women with a prior history of preterm birth.
Published Molecules found in mucus can thwart fungal infection (via sciencedaily.com)
Researchers have identified components of mucus that can specifically interact with the fungus Candida albicans and prevent it from causing infection. These molecules, known as glycans, are a major constituent of mucins, the gel-forming polymers that make up mucus.
Published Cryogenic electron microscopy reveals drug targets against common fungus (via sciencedaily.com) Original source
Scientists have used single-particle cryogenic electron microscopy to determine the structure of the ribosome of Candida albicans. Their results reveal a potential target for new drugs.
Published Emergency caesarean placenta response (via sciencedaily.com)
Labour and natural childbirth causes stress on a mother's body but an emergency Caesarean is associated with even more inflammatory gene expression in the placenta, new South Australian research shows. The study investigated differences in placenta inflammation markers after delivery of both male and female babies involved in 20 emergency Caesarean procedures - compared with 40 placentas from vaginal (or 'natural') deliveries and 10 placentas from an elective C-section at an Adelaide public maternity hospital between 2006 and 2018.
Published Viral transformations in the female genital tract can spell trouble for women’s health (via sciencedaily.com)
A new study uses next-generation gene sequencing to get a clearer read on the community of viruses present in vaginal microbiome samples and its implication for the development of cervical cancer.
Published Toxin-producing yeast strains in gut fuel IBD (via sciencedaily.com) Original source
Individual Candida albicans yeast strains in the human gut are as different from each other as the humans that carry them, and some C. albicans strains may damage the gut of patients with inflammatory bowel disease (IBD), according to a new study. The findings suggest a possible way to tailor treatments to individual patients in the future.
Published Pathogen and drug work together to fight fungal lung infection (via sciencedaily.com) Original source
Pathogens don't always work against drug treatments. Sometimes, they can strengthen them, according to new research. Researchers have now looked at two pathogens that often occur at similar sites, particularly in cystic fibrosis and mechanically ventilated patients: Candida albicans and Pseudomonas aeruginosa. The researchers investigated the effectiveness of an antifungal drug, fluconazole, with both pathogens. The results showed that P. aeruginosa works with fluconazole to eliminate drug tolerance and clear the C. albicans infection. The bacteria also enhance the drug's ability against a second pathogenic Candida species that tends to be more resistant to the drug.