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Categories: Bipolar Disorder, Gynecology

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Fertility Gynecology
Published

Elimination of type of bacteria suggests treatment for endometriosis      (via sciencedaily.com)     Original source 

A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.

Depression Gynecology Mental Health Research Psychology Research
Published

Dynamic expression of brain serotonin receptors across the menstrual cycle provides clues about premenstrual dysphoric disorder      (via sciencedaily.com)     Original source 

A new study explores the interplay between the serotonin system and estradiol in the brain, showing that the central nervous system in patients with premenstrual dysphoric disorder (PMDD) seems to increase serotonin transporter density from the periovulatory phase (when estradiol levels are high) to premenstrual cycle phase (when both estradiol and progesterone are decreasing). The findings have the potential to advance the clinical treatment of PMDD.

Gynecology Menopause Women's Health - General
Published

Migraines during menstruation: Low estrogen levels paired with higher CGRP levels may jump start migraine      (via sciencedaily.com)     Original source 

As estrogen levels fluctuate, a new study has found for female participants with migraine, their levels of the protein calcitonin gene-related peptide (CGRP) that plays a key role in starting the migraine process also fluctuate.

Gynecology Healthy Aging Menopause Pregnancy and Childbirth Today's Healthcare Women's Health - General
Published

Does lifetime exposure to estrogen affect risk of stroke?      (via sciencedaily.com) 

People with a higher cumulative estrogen exposure throughout their life may have a lower risk of stroke, according to a new study. The lower risk was found for both ischemic stroke and intracerebral hemorrhage.

Bipolar Disorder Depression Mental Health Research
Published

New study reveals differences in diagnosis of psychiatric disorders between geographies      (via sciencedaily.com) 

Diagnosing psychiatric disorders is challenging due to the lack of objective tests. Fortunately, genomic studies can reveal genes associated with increased risk of certain disorders. In a recent study, researchers from Japan investigated whether the genetic correlations between major psychiatric disorders differed among European and East Asian populations. They showed differences in how bipolar disorders are diagnosed by psychiatrists in the East and the West, which might affect the results of clinical trials.

Gynecology Infant's Health Pregnancy and Childbirth Women's Health - General
Published

Birth choices after previous cesarean and risk of pelvic floor surgery      (via sciencedaily.com)     Original source 

Vaginal birth after a previous cesarean section is associated with an increased risk of pelvic floor surgery compared with planning another cesarean, according to a new study. The findings provide useful information to help women who have had a previous cesarean section when planning how to give birth in their next pregnancy.

Gynecology
Published

Fungal association with tumors may predict worse outcomes      (via sciencedaily.com) 

The presence of some fungal species in tumors predicts -- and may even help drive -- worse cancer outcomes, according to a new study.

Gynecology
Published

Advanced imaging sheds light on immune escape of shape-shifting fungus      (via sciencedaily.com)     Original source 

Fungal pathogens have a major global impact upon human health -- they are often difficult to diagnose and treat, and there is an urgent need for better diagnostics and more effective antifungal treatments. Using newly developed imaging technologies, researchers have now revealed how Candida albicans, a common fungus, evades immune responses. According to the researchers this involves an 'alien-like' shape shifting that allows the fungus to break out of immune cells.

Gynecology Hormone Disorders Menopause Women's Health - General
Published

Data on cancer risk from hormone therapy 'reassuring,' menopause experts say      (via sciencedaily.com)     Original source 

A new scientific paper and other recent evidence offer important reassurances about the risk of breast cancer from hormone therapy to treat menopause symptoms, two menopause experts say.

Gynecology
Published

Curbing Candida: The cells that keep fungal infections at bay      (via sciencedaily.com)     Original source 

Researchers have uncovered a previously unknown defense mechanism employed by the immune system in fighting Candida infections.

Gynecology Hormone Disorders Menopause
Published

Women burn fat even after menopause      (via sciencedaily.com)     Original source 

The estrogen deficiency following menopause is thought to impair women's ability to use fat as an energy source. A study shows that menopausal state or blood estrogen levels do not clearly determine the rate middle-aged women are able to use fat at rest or during exercise. Higher fat utilization did not indicate better glucose tolerance.

Fertility Gynecology
Published

Uterine transplantation is efficacious and safe, study suggests      (via sciencedaily.com) 

Transplanting a uterus is an effective, safe method to remedy infertility when a functioning uterus is lacking. This is the conclusion from a thorough study of uterine transplantation.

Gynecology
Published

Progress toward personalized prevention of preterm birth: When progesterone works and when it does not      (via sciencedaily.com)     Original source 

The most effective intervention to prevent preterm birth is the administration of a natural hormone, progesterone, in patients at risk for premature delivery. Two categories of patients have been eligible for this treatment: those with a short cervix and those with a previous preterm birth. But new research indicates that progesterone is not effective in reducing the rate of preterm birth in women with a prior history of preterm birth.

Gynecology
Published

Molecules found in mucus can thwart fungal infection      (via sciencedaily.com) 

Researchers have identified components of mucus that can specifically interact with the fungus Candida albicans and prevent it from causing infection. These molecules, known as glycans, are a major constituent of mucins, the gel-forming polymers that make up mucus.

Gynecology
Published

Cryogenic electron microscopy reveals drug targets against common fungus      (via sciencedaily.com)     Original source 

Scientists have used single-particle cryogenic electron microscopy to determine the structure of the ribosome of Candida albicans. Their results reveal a potential target for new drugs.

Bipolar Disorder Eating Disorder Research Eating Disorders
Published

Multiple diagnoses are the norm for mental illness; A new genetic analysis helps explain why      (via sciencedaily.com)     Original source 

An analysis of 11 major psychiatric disorders offers new insight into why comorbidities are the norm when it comes to mental illness. The study suggests that while there is no single gene or set of genes underlying risk for all of them, subsets of disorders -- including bipolar disorder and schizophrenia; anorexia nervosa and obsessive-compulsive disorder; and major depression and anxiety --s hare a common genetic architecture.

Gynecology
Published

Emergency caesarean placenta response      (via sciencedaily.com) 

Labour and natural childbirth causes stress on a mother's body but an emergency Caesarean is associated with even more inflammatory gene expression in the placenta, new South Australian research shows. The study investigated differences in placenta inflammation markers after delivery of both male and female babies involved in 20 emergency Caesarean procedures - compared with 40 placentas from vaginal (or 'natural') deliveries and 10 placentas from an elective C-section at an Adelaide public maternity hospital between 2006 and 2018.

Gynecology Sexual Health
Published

Viral transformations in the female genital tract can spell trouble for women’s health      (via sciencedaily.com) 

A new study uses next-generation gene sequencing to get a clearer read on the community of viruses present in vaginal microbiome samples and its implication for the development of cervical cancer.

Bipolar Disorder
Published

Evidence of brain changes in those at risk of bipolar disorder captured with MRI scans      (via sciencedaily.com) 

A study that showed changes in the brain in those at risk of developing bipolar disorder raises new hopes about early intervention.

Bipolar Disorder
Published

Lithium may decrease risk of developing dementia      (via sciencedaily.com)     Original source 

Researchers have identified a link suggesting that lithium could decrease the risk of developing dementia, which affects nearly one million people in the UK.