Showing 20 articles starting at article 1
Published Research challenges current thinking on the genetic causes of very early menopause (via sciencedaily.com) Original source
The genetic causes of very early menopause will have to be reconsidered after researchers found that nearly all women who carried variations thought to cause the condition in fact had their menopause at an older age.
Published One in five women become pregnant naturally after having a baby conceived with IVF (via sciencedaily.com) Original source
New research analyzed data from 11 studies of over 5,000 women around the world between 1980 and 2021, to evaluate how common it is to get pregnant naturally after having a baby conceived by fertility treatment. Around 20% of women who needed fertility treatment, such as IVF, to conceive their first child are likely to get pregnant naturally in the future, finds a new study.
Published New diagnostic finds intact sperm in infertile men (via sciencedaily.com) Original source
Researchers develop new diagnostic tool to visualize protein biomarkers of well-developed sperm to determine if surgical sperm extraction may be successful for certain infertile men.
Published Elimination of type of bacteria suggests treatment for endometriosis (via sciencedaily.com) Original source
A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.
Published Researchers successfully induce primate oocytes in the lab (via sciencedaily.com) Original source
The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.
Published Happy worms have healthy eggs (via sciencedaily.com) Original source
Researchers have exposed roundworms (a well-established model organism in biological research) to selective serotonin reuptake inhibitors (SSRIs), a class of drugs used for treating depression and anxiety. Surprisingly, this treatment improved the quality of aging females' egg cells.
Published Scientists discover the dynamics of an 'extra' chromosome in fruit flies (via sciencedaily.com) Original source
Most chromosomes have been around for millions of years. Now, researchers have revealed the dynamics of a new, very young chromosome in fruit flies that is similar to chromosomes that arise in humans and is associated with treatment-resistant cancer and infertility. The findings may one day lead to developing more targeted therapies for treating these conditions.
Published Diet high in fruit and vegetables linked to lower miscarriage risk (via sciencedaily.com) Original source
A preconception and early-pregnancy diet that contains lots of fruit, vegetables, seafood, dairy, eggs and grain may be associated with reducing risk of miscarriage, a new review of research suggests.
Published New genetic target for male contraception identified (via sciencedaily.com) Original source
Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.
Published Time-restricted fasting could cause fertility problems (via sciencedaily.com) Original source
Researchers have found that time-restricted fasting could cause fertility problems. Time-restricted fasting is an eating pattern where people limit their food consumption to certain hours of the day. It's a popular health and fitness trend and people are doing it to lose weight and improve their health. But the new study shows that time-restricted fasting affects reproduction differently in male and female zebrafish. Importantly, some of the negative effects on eggs and sperm quality can be seen after the fish returned to their normal levels of food consumption. The research team say that while the study was conducted in fish, their findings highlight the importance of considering not just the effect of fasting on weight and health, but also on fertility.
Published New technology to select healthier sperm for IVF success (via sciencedaily.com) Original source
Scientists have developed new technology to help couples undergoing in-vitro fertilization (IVF) due to male fertility problems to increase their chances of success in having a baby.
Published Ending THC use may reverse its impacts on male fertility, research shows (via sciencedaily.com) Original source
A previous study confirmed that chronic use of cannabis may greatly impact male fertility and reproductive outcomes in nonhuman primates -- but it was unclear whether the effects are permanent. Now, new research has confirmed that discontinuing use of THC can at least partly reverse these effects, according to a new study.
Published Disproportionate percentage of females with unexplained infertility have gene variants known to cause heart problems, cancer (via sciencedaily.com) Original source
About 17% of women with unexplained infertility also have gene variants known to cause disease, from common conditions like heart disease to rare problems like ALS, researchers report.
Published Humans bite back by deactivating mosquito sperm (via sciencedaily.com) Original source
New research makes it likely that proteins responsible for activating mosquito sperm can be shut down, preventing them from swimming to or fertilizing eggs.
Published Researchers discover way to reverse infertility by reducing HDL cholesterol (via sciencedaily.com) Original source
Scientists reversed infertility in sterile mice by reducing HDL cholesterol with a bacterial protein in a promising development that shows further evidence linking high cholesterol to female infertility. The researchers worked with a protein called serum opacity factor that lowered cholesterol levels by over 40% in three hours.
Published Dynamic expression of brain serotonin receptors across the menstrual cycle provides clues about premenstrual dysphoric disorder (via sciencedaily.com) Original source
A new study explores the interplay between the serotonin system and estradiol in the brain, showing that the central nervous system in patients with premenstrual dysphoric disorder (PMDD) seems to increase serotonin transporter density from the periovulatory phase (when estradiol levels are high) to premenstrual cycle phase (when both estradiol and progesterone are decreasing). The findings have the potential to advance the clinical treatment of PMDD.
Published Migraines during menstruation: Low estrogen levels paired with higher CGRP levels may jump start migraine (via sciencedaily.com) Original source
As estrogen levels fluctuate, a new study has found for female participants with migraine, their levels of the protein calcitonin gene-related peptide (CGRP) that plays a key role in starting the migraine process also fluctuate.
Published Physically demanding work tied to higher male fertility, study suggests (via sciencedaily.com) Original source
A new study suggests that men who regularly lift heavy objects at work have higher sperm counts.
Published High infant mortality rates and global human population rise (via sciencedaily.com) Original source
New research showing high infant mortality rates are contributing to an incessant rise of the global human population supports arguments for greater access to contraception and family planning in low- and middle-income nations.
Published On-demand male contraceptive shows promise in preclinical study (via sciencedaily.com) Original source
An experimental contraceptive drug temporarily stops sperm in their tracks and prevents pregnancies in preclinical models. The study demonstrates that an on-demand male contraceptive is possible.