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Chronic Illness Psychology Research
Published

Cracking the code of neurodegeneration: New model identifies potential therapeutic target      (via sciencedaily.com)     Original source 

Scientists have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration. Their research pinpointed a misbehaving protein as a promising therapeutic target in the treatment of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

Psychology Research
Published

Uncovering anxiety: Scientists identify causative pathway and potential cures      (via sciencedaily.com)     Original source 

Quick-acting targeted therapies with minimal side effects are an urgent need for the treatment of anxiety-related disorders. While delta opioid receptor (DOP) agonists have shown 'anxiolytic' or anxiety-reducing effects, their mechanism of action is not well-understood. A new study highlights the role of specific neuronal circuits in the brain involved in the development of anxiety, and distinct mechanisms of action of the therapeutic DOP agonist -- KNT-127.

Healthy Aging Psychology Research
Published

Air pollution linked to more signs of Alzheimer's in brain      (via sciencedaily.com)     Original source 

People with higher exposure to traffic-related air pollution were more likely to have high amounts of amyloid plaques in their brains associated with Alzheimer's disease after death, according to a new study. Researchers looked at fine particulate matter, PM2.5, which consists of pollutant particles of less than 2.5 microns in diameter suspended in air.

Psychology Research Today's Healthcare
Published

How does the brain make decisions?      (via sciencedaily.com)     Original source 

Mouse study provides insights into communication between neurons during decision-making.

Psychology Research
Published

Possible trigger for autoimmune diseases discovered : B cells teach T cells which targets must not be attacked      (via sciencedaily.com)     Original source 

Immune cells must learn not to attack the body itself. A team of researchers has discovered a previously unknown mechanism behind this: other immune cells, the B cells, contribute to the 'training' of the T cells in the thymus gland. If this process fails, autoimmune diseases can develop. The study confirms this for Neuromyelitis optica, a disease similar to Multiple Sclerosis. Other autoimmune diseases may be linked to the failure of this new mechanism as well.

Chronic Illness Psychology Research
Published

Mapping potential pathways to MND treatment      (via sciencedaily.com)     Original source 

Researchers have mapped out the proteins implicated in the early stages of motor neurone disease (MND). They have developed a longitudinal map of the proteins involved in MND across the trajectory of the disease, identifying potential therapeutic pathways for further investigation.

Depression Psychology Research
Published

Modifying brain molecule relaxin-3 can potentially reduce side effects in treating anxiety, depression and more      (via sciencedaily.com)     Original source 

A team of researchers has found a potential way to treat conditions like depression and anxiety with fewer side effects.

Psychology Research
Published

Blocking key protein may halt progression of Alzheimer's disease      (via sciencedaily.com)     Original source 

Researchers have found that inhibiting a key protein can stop the destruction of synapses and dendritic spines commonly seen in Alzheimer's disease.

Birth Defects Child Development Children's Health Depression Infant's Health Mental Health Research Parenting Pregnancy and Childbirth Psychology Research Today's Healthcare
Published

Stress during pregnancy can lead to early maturation of first-born daughters      (via sciencedaily.com)     Original source 

Researchers have found a correlation between early signs of adrenal puberty in first-born daughters and their mothers' having experienced high levels of prenatal stress. They did not find the same result in boys or daughters who were not first-born.

Chronic Illness Healthy Aging Psychology Research
Published

Exposure to Agent Orange damages brain tissue in ways similar to Alzheimer's disease      (via sciencedaily.com)     Original source 

Agent Orange, an herbicide used during the Vietnam War, is a known toxin with wide-ranging health effects. Even though Agent Orange has not been used for decades, there is increasing interest in its effects on the brain health of aging veterans. A new study reveals the mechanisms by which Agent Orange affects the brain and how those processes can lead to neurodegenerative diseases. The research shows that exposures to Agent Orange herbicidal chemicals damage frontal lobe brain tissue of laboratory rats with molecular and biochemical abnormalities that are similar to those found in early-stage Alzheimer's disease.

Cosmetic Surgery Cosmetics Healthy Aging Skin Care
Published

Turning back the clock on photoaging skin      (via sciencedaily.com)     Original source 

A new study examines dermal injections and their impact on skin aging.

Psychology Research
Published

Neuronal insights: Flash and freeze-fracture      (via sciencedaily.com)     Original source 

Fear and addiction exert significant influence within society. Managing them is often challenging, as they are driven by intricate neuronal circuits in our brains. Understanding the underlying molecular mechanisms is crucial to intervene when these processes malfunction. The novel 'Flash and Freeze-fracture' technique provides a unique glimpse into the respective brain region.

Psychology Research
Published

Neural prosthetic device can help humans restore memory      (via sciencedaily.com)     Original source 

A team of scientists have demonstrated the first successful use of a neural prosthetic device to recall specific memories.

Child Development Psychology Research
Published

Are you depressed? Scents might help      (via sciencedaily.com)     Original source 

Smelling a familiar scent can help depressed individuals recall specific autobiographical memories and potentially assist in their recovery.

Healthy Aging Psychology Research
Published

Immune genes are altered in Alzheimer's patients' blood      (via sciencedaily.com)     Original source 

A new study has found the immune system in the blood of Alzheimer's patients is epigenetically altered. That means the patients' behavior or environment has caused changes that affect the way their genes work. Many of these altered immune genes are the same ones that increase an individual's risk for Alzheimer's. Scientists now theorize the cause could be a previous viral infection, environmental pollutants or other lifestyle factors and behaviors.

Child Development Psychology Research
Published

How emotions affect word retrieval in people with aphasia      (via sciencedaily.com)     Original source 

People with aphasia have more trouble coming up with words they want to use when they're prompted by images and words that carry negative emotional meaning, new research suggests.

Children's Health Psychology Research
Published

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme      (via sciencedaily.com)     Original source 

Scientists have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most common types of genetic epilepsy.

Birth Defects Child Development Infant's Health Parenting Psychology Research
Published

Patterns of brain connectivity differ between pre-term and term babies      (via sciencedaily.com)     Original source 

A new scanning study of 390 babies has shown distinct patterns between term and pre-term babies in the moment-to-moment activity and connectivity of brain networks.

Chronic Illness Psychology Research
Published

Pharmacological inhibitor protects nerve cells in ALS disease      (via sciencedaily.com)     Original source 

A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease amyotrophic lateral sclerosis (ALS). Neurobiologists examined a neuroprotective molecule that belongs to a novel drug class. It is able to inhibit the interactions of certain proteins and has been successfully tested in a mouse model of ALS and in brain organoids of ALS patients.

Birth Defects Chronic Illness Depression Mental Health Research Pregnancy and Childbirth Psychology Research
Published

Researchers make progress toward developing blood tests for psychiatric and neurological disorders      (via sciencedaily.com)     Original source 

Researchers used genetic material from human blood and lab-grown brain cells say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.