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Categories: Cosmetics, Gynecology

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Scientists have 3D-printed hair follicles in human skin tissue cultured in the lab. This marks the first time researchers have used the technology to generate hair follicles, which play an important role in skin healing and function. When it comes to engineering human skin, hair may at first seem superfluous. However, hair follicles are quite important: They produce sweat, helping regulate body temperature, and they contain stem cells that help skin heal. The finding has potential applications in regenerative medicine and drug testing, though engineering skin grafts that grow hair are still several years away.  

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Using birth control pills and other hormone-based contraceptives is known to elevate the risk of blood clots, but a new study suggests that this risk largely goes away within two to four weeks after one stops using these contraceptives. The findings can help patients and doctors weigh the benefits and risks of hormonal contraceptives and guide when to stop using them ahead of events that could further increase the risk of dangerous clots, such as major surgery, prolonged periods of immobility, or when tapering anticoagulant medications after a blood clot.

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Scientists have published the first successful application of 2-photon intravital microscopy (IVM) to image the dynamics of fungal infections in the kidney of a living host. The study reveals that the opportunistic human fungal pathogen Candida albicans requires the ability to metabolize proline, an amino acid obtained from the host, to mount virulent infections.

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Researchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered to be at the center of the development of Alzheimer's disease.

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Researchers have shown that pregnancy hormones ‘rewire’ the brain to prepare mice for motherhood. The findings show that both estrogen and progesterone act on a small population of neurons in the brain to switch on parental behavior even before offspring arrive. These adaptations resulted in stronger and more selective responses to pups.

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A study led by obstetricians has shown that a new device can rapidly control postpartum hemorrhage, a major cause of severe maternal morbidity and death, in a wide range of patients.

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A new study finds that a natural compound found in many plants inhibits the growth of drug-resistant Candida fungi -- including its most virulent species, Candida auris, an emerging global health threat.

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A new study examines why people living in Atlantic regions are more at-risk for developing melanoma than other Canadians, providing lessons on skin cancer prevention for the whole country. To find out why, the researchers compared UV exposure and behaviours among different groups in Atlantic Canada based on income, education, and gender, among other factors.

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Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research.

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Researchers have discovered a new way to attack fungal infections. The key is to block fungi from being able to make fatty acids, the major component of fats. Resistance to anti-fungal drugs is increasing and this new approach will be particularly useful because it works in a new way and affects a broad range of fungal species.

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A study explores how ultraviolet radiation can alter the microstructure of human skin. Particularly affected is collagen, the fibrous protein that binds together tissue, tendon, cartilage and bone throughout our bodies.

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In a pre-clinical, proof-of-concept study, researchers found that epigallocatechin gallate (EGCG), a green tea compound with powerful antioxidant properties, could be promising for both treating and preventing uterine fibroids. Results of the study add to growing evidence that EGCG may reduce fibroid cell growth. The study was specifically designed to identify the biochemical mechanisms responsible for EGCG action in fibroid cells.

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A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.

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Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.

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The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.

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A new study explores the interplay between the serotonin system and estradiol in the brain, showing that the central nervous system in patients with premenstrual dysphoric disorder (PMDD) seems to increase serotonin transporter density from the periovulatory phase (when estradiol levels are high) to premenstrual cycle phase (when both estradiol and progesterone are decreasing). The findings have the potential to advance the clinical treatment of PMDD.

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As estrogen levels fluctuate, a new study has found for female participants with migraine, their levels of the protein calcitonin gene-related peptide (CGRP) that plays a key role in starting the migraine process also fluctuate.

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People with a higher cumulative estrogen exposure throughout their life may have a lower risk of stroke, according to a new study. The lower risk was found for both ischemic stroke and intracerebral hemorrhage.

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In a study of patients with a history of facial keratinocyte carcinoma, 20.9% of those treated with nonablative fractional lasers experienced a subsequent keratinocyte carcinoma, compared with 40.4% of patients who did not receive laser treatment.

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The ultraviolet nail polish drying devices used to cure gel manicures may pose more of a public health concern than previously thought. Researchers studied these ultraviolet (UV) light-emitting devices, and found that their use leads to cell death and cancer-causing mutations in human cells.