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Categories: Bipolar Disorder, Fertility

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People who have recovered from a major depressive episode, when compared with individuals who have never experienced one, tend to spend more time processing negative information and less time processing positive information, putting them at risk for a relapse, according to new research.

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Treatment with modern antidepressants may help prevent patients with bipolar disorder from relapsing into a depressive episode, according to an international clinical trial. The findings challenge current clinical practice guidelines and could change how bipolar depression is managed globally.

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The genetic causes of very early menopause will have to be reconsidered after researchers found that nearly all women who carried variations thought to cause the condition in fact had their menopause at an older age.

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New research analyzed data from 11 studies of over 5,000 women around the world between 1980 and 2021, to evaluate how common it is to get pregnant naturally after having a baby conceived by fertility treatment. Around 20% of women who needed fertility treatment, such as IVF, to conceive their first child are likely to get pregnant naturally in the future, finds a new study.

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Researchers develop new diagnostic tool to visualize protein biomarkers of well-developed sperm to determine if surgical sperm extraction may be successful for certain infertile men.

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A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.

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The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.

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Researchers have exposed roundworms (a well-established model organism in biological research) to selective serotonin reuptake inhibitors (SSRIs), a class of drugs used for treating depression and anxiety. Surprisingly, this treatment improved the quality of aging females' egg cells.

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Most chromosomes have been around for millions of years. Now, researchers have revealed the dynamics of a new, very young chromosome in fruit flies that is similar to chromosomes that arise in humans and is associated with treatment-resistant cancer and infertility. The findings may one day lead to developing more targeted therapies for treating these conditions.

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A preconception and early-pregnancy diet that contains lots of fruit, vegetables, seafood, dairy, eggs and grain may be associated with reducing risk of miscarriage, a new review of research suggests.

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Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.

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Researchers have found that time-restricted fasting could cause fertility problems. Time-restricted fasting is an eating pattern where people limit their food consumption to certain hours of the day. It's a popular health and fitness trend and people are doing it to lose weight and improve their health. But the new study shows that time-restricted fasting affects reproduction differently in male and female zebrafish. Importantly, some of the negative effects on eggs and sperm quality can be seen after the fish returned to their normal levels of food consumption. The research team say that while the study was conducted in fish, their findings highlight the importance of considering not just the effect of fasting on weight and health, but also on fertility.

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Scientists have developed new technology to help couples undergoing in-vitro fertilization (IVF) due to male fertility problems to increase their chances of success in having a baby.

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A previous study confirmed that chronic use of cannabis may greatly impact male fertility and reproductive outcomes in nonhuman primates -- but it was unclear whether the effects are permanent. Now, new research has confirmed that discontinuing use of THC can at least partly reverse these effects, according to a new study.

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About 17% of women with unexplained infertility also have gene variants known to cause disease, from common conditions like heart disease to rare problems like ALS, researchers report.

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New research makes it likely that proteins responsible for activating mosquito sperm can be shut down, preventing them from swimming to or fertilizing eggs.

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Scientists reversed infertility in sterile mice by reducing HDL cholesterol with a bacterial protein in a promising development that shows further evidence linking high cholesterol to female infertility. The researchers worked with a protein called serum opacity factor that lowered cholesterol levels by over 40% in three hours.

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A new study suggests that men who regularly lift heavy objects at work have higher sperm counts.

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New research showing high infant mortality rates are contributing to an incessant rise of the global human population supports arguments for greater access to contraception and family planning in low- and middle-income nations.

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An experimental contraceptive drug temporarily stops sperm in their tracks and prevents pregnancies in preclinical models. The study demonstrates that an on-demand male contraceptive is possible.