Showing 20 articles starting at article 1
Categories: Fertility, Neuropathy
Published Body's immune response may offer alternative approach to neuropathic pain therapies
(via sciencedaily.com) Original source In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe.
Published Research challenges current thinking on the genetic causes of very early menopause
(via sciencedaily.com) Original source The genetic causes of very early menopause will have to be reconsidered after researchers found that nearly all women who carried variations thought to cause the condition in fact had their menopause at an older age.
Published One in five women become pregnant naturally after having a baby conceived with IVF
(via sciencedaily.com) Original source New research analyzed data from 11 studies of over 5,000 women around the world between 1980 and 2021, to evaluate how common it is to get pregnant naturally after having a baby conceived by fertility treatment. Around 20% of women who needed fertility treatment, such as IVF, to conceive their first child are likely to get pregnant naturally in the future, finds a new study.
Published Pregnancy hormone repairs myelin damage in MS mouse model
(via sciencedaily.com) Original source A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
Published New diagnostic finds intact sperm in infertile men
(via sciencedaily.com) Original source Researchers develop new diagnostic tool to visualize protein biomarkers of well-developed sperm to determine if surgical sperm extraction may be successful for certain infertile men.
Published Elimination of type of bacteria suggests treatment for endometriosis
(via sciencedaily.com) Original source A research group has discovered that using an antibiotic to target Fusobacterium, a common bacterium that causes inflammation, improved the symptoms of endometriosis. Their findings suggest an alternative treatment for the disease.
Published Researchers successfully induce primate oocytes in the lab
(via sciencedaily.com) Original source The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers to control the differentiation of stem cells in the lab (in vitro). Of particular interest are oocytes, which are female germ cells that develop into eggs. Understanding their development could have far-ranging impacts, from infertility treatment to conservation of endangered species. A new study has successfully induced meiotic (dividing) oocytes from the embryonic stem cells of cynomolgus monkeys, which share many physiological traits with humans. By establishing a culture method for inducing the differentiation of meiotic oocytes, the researchers aimed to shed light on germ cell development in both humans and other primates.
Published New chemical compound demonstrates potential in nerve regeneration
(via sciencedaily.com) Original source Recent research has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen in heart attack.
Published Happy worms have healthy eggs
(via sciencedaily.com) Original source Researchers have exposed roundworms (a well-established model organism in biological research) to selective serotonin reuptake inhibitors (SSRIs), a class of drugs used for treating depression and anxiety. Surprisingly, this treatment improved the quality of aging females' egg cells.
Published Scientists discover the dynamics of an 'extra' chromosome in fruit flies
(via sciencedaily.com) Original source Most chromosomes have been around for millions of years. Now, researchers have revealed the dynamics of a new, very young chromosome in fruit flies that is similar to chromosomes that arise in humans and is associated with treatment-resistant cancer and infertility. The findings may one day lead to developing more targeted therapies for treating these conditions.
Published Neuropathic pain: The underlying mechanism and a potential therapeutic target are revealed in mice
(via sciencedaily.com) Original source Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV. Researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic pain. Moreover, they show that targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviated neuropathic pain hypersensitivity.
Published How alcohol consumption contributes to chronic pain
(via sciencedaily.com) Original source A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.
Published Diet high in fruit and vegetables linked to lower miscarriage risk
(via sciencedaily.com) Original source A preconception and early-pregnancy diet that contains lots of fruit, vegetables, seafood, dairy, eggs and grain may be associated with reducing risk of miscarriage, a new review of research suggests.
Published New genetic target for male contraception identified
(via sciencedaily.com) Original source Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals. Researchers identified expression of the gene, Arrdc5, in the testicular tissue of mice, pigs, cattle and humans. When they knocked out the gene in mice, it created infertility only in the males, impacting their sperm count, movement and shape.
Published Genetic therapy corrects progressive muscle disorder in mice
(via sciencedaily.com) Original source Investigators recently used a targeted drug to restore muscle strength and correct myotonia in mice with myotonic dystrophy.
Published Students engineer socks for on-the-go neuropathy treatment
(via sciencedaily.com) Original source A wearable electrical-stimulation and vibration-therapy system designed by engineering students might be just what the doctor ordered for people experiencing foot pain and balance loss due to diabetic neuropathy.
Published Time-restricted fasting could cause fertility problems
(via sciencedaily.com) Original source Researchers have found that time-restricted fasting could cause fertility problems. Time-restricted fasting is an eating pattern where people limit their food consumption to certain hours of the day. It's a popular health and fitness trend and people are doing it to lose weight and improve their health. But the new study shows that time-restricted fasting affects reproduction differently in male and female zebrafish. Importantly, some of the negative effects on eggs and sperm quality can be seen after the fish returned to their normal levels of food consumption. The research team say that while the study was conducted in fish, their findings highlight the importance of considering not just the effect of fasting on weight and health, but also on fertility.
Published Bariatric surgery may reverse diabetes complications for people with obesity
(via sciencedaily.com) Original source For more than 100 million Americans who are obese, bariatric surgery may reverse complications related to diabetes, including regenerating damaged nerves, a new study shows. Researchers say the findings suggest that bariatric surgery likely enables the regeneration of the peripheral nerves and, therefore, may be an effective treatment for millions of individuals with obesity who are at risk of developing diabetes and peripheral neuropathy,
Published New technology to select healthier sperm for IVF success
(via sciencedaily.com) Original source Scientists have developed new technology to help couples undergoing in-vitro fertilization (IVF) due to male fertility problems to increase their chances of success in having a baby.
Published Fibromyalgia: Pain out of control
(via sciencedaily.com) Original source Feeling like we have a degree of control makes us tolerate pain better. In the case of fibromyalgia, however, this simply doesn't work. A study provides clues as to why.