Showing 20 articles starting at article 1
Published That smell: New gut microbe produces smelly toxic gas but protects against pathogens (via sciencedaily.com)
Microbiologists have discovered a new intestinal microbe that feeds exclusively on taurine and produces the foul-smelling gas hydrogen sulfide. The researchers have thus provided another building block in the understanding of those microbial processes that have fascinating effects on health. This is also true of Taurinivorans muris: the bacterium shows a protective function against Klebsiella and Salmonella, two important pathogens.
Published Living in a disadvantaged neighborhood affects food choices, weight gain and the microstructure of the brain (via sciencedaily.com)
A new study finds poor quality of available foods, increased intake of calories from foods high in trans-fatty acids, and environments that do not foster physical activity, all prevalent in disadvantaged neighborhoods, disrupt the flexibility of information processing in the brain that is involved in reward, emotion regulation, and cognition.
Published ER-positive breast cancer presents differing metabolic signatures in African American, white women (via sciencedaily.com)
New research has found that estrogen receptor-positive breast cancer presents differing metabolic signatures in the blood of African American women and non-Hispanic white women.
Published The human lipidome reveals new indicators of health, disease and aging (via sciencedaily.com)
A new survey of an under-explored aspect of human biology uncovers the many roles of the body's 'greasy molecules.'
Published New insights into melanoma development and therapy (via sciencedaily.com)
Researchers have revealed that the expression of a specific isoform of GREB1 Is4 is induced in malignant melanoma cells by the melanocyte-specific transcription factor, MITF. They revealed that GREB1 Is4 stimulates pyrimidine biosynthesis and promotes cancer cell proliferation. Furthermore, the anti-tumor effect of antisense nucleic acids against GREB1 showed a potential new modality for malignant melanoma.
Published First-in-class targeted microRNA therapy slows cancer tumor growth (via sciencedaily.com)
A new cancer therapy attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division.
Published Antioxidants stimulate blood flow in tumors (via sciencedaily.com)
Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumors, a new study shows. The discovery corroborates the idea that dietary supplements containing antioxidants can accelerate tumor growth and metastasis.
Published How to help prevent childhood stunting (via sciencedaily.com)
A new study shows that adding zinc to farmland soil can help prevent childhood stunting, a condition due to chronic undernutrition that is associated with poor brain development and long-lasting harmful consequences, such as reduced school performance and increased disease risks.
Published New study reveals anti-cancer properties in Kencur ginger (via sciencedaily.com)
Scientists have verified the anticancer effects of Kencur, a tropical plant of the ginger family, mainly grown in Southeast Asia, in cell and animal experiments. They found that Kencur extract and its main active components significantly inhibit cancer cell growth at the cellular and animal levels. Furthermore, the involvement of TFAM in the mechanism of action was confirmed.
Published Connections between drinking water quality and increased lung infections in people with cystic fibrosis (via sciencedaily.com)
High levels of some minerals and metals in environmental water supplies may increase the risk of nontuberculous mycobacteria (NTM) pulmonary infections in people with cystic fibrosis, according to a new study. The study found the presence of the metals molybdenum and vanadium along with sulfate -- a collection of mineral salts -- in the U.S. municipal water system was associated with an increased incidence of NTM pulmonary infections, the leading cause of drinking-water associated illnesses.
Published Gene therapy study identifies potential new treatment for liver cancer (via sciencedaily.com)
Gene therapy with microRNA-22 produced better survival outcomes than the current FDA-approved drug for liver cancer and without noticeable toxicity in new mouse study.
Published Preterm babies given certain fatty acids have better vision (via sciencedaily.com)
Preterm babies given a supplement with a combination of omega-3 and omega-6 fatty acids have better visual function by the age of two and a half.
Published Positive metabolic effects of gastric bypass disappear quickly (via sciencedaily.com)
A new study raises questions about the efficacy of bariatric operations involving gastric bypass. The results show that the biggest metabolic changes happened directly after surgery. Just a year after the operation, the concentration of metabolites and fats had returned to almost the same levels as before the procedure.
Published Tropical plant native to China reveals antiobesity potential (via sciencedaily.com)
Scientists tested the antiobesity effects of Mallotus furetianus extract native to Hainan Island, China, using obesity model mice. As a result, body weight and adipose tissue weight of obesity model mice were significantly reduced by the intake of Mallotus furetianus extract. Fatty liver was suppressed and adipocyte size reduction in adipose tissue was observed. Further investigation into the mechanism revealed that fat synthesis is inhibited by suppressing the expression of several transcription factors involved in differentiation into adipocytes.
Published Deadly fungus beaten with new type of treatment (via sciencedaily.com)
Researchers have discovered a new way to attack fungal infections. The key is to block fungi from being able to make fatty acids, the major component of fats. Resistance to anti-fungal drugs is increasing and this new approach will be particularly useful because it works in a new way and affects a broad range of fungal species.
Published Omega-3 fatty acids appear promising for maintaining lung health (via sciencedaily.com)
Omega-3 fatty acids, which are abundant in fish and fish oil supplements, appear promising for maintaining lung health, according to new evidence from a large, multi-faceted study in healthy adults. The study provides the strongest evidence to date of this association and underscores the importance of including omega-3 fatty acids in the diet, especially given that many Americans do not meet current guidelines.
Published Do certain amino acids modify the risk of dementia linked to air pollution? (via sciencedaily.com)
Higher levels of vitamin B-related amino acids may be linked to the risk of dementia associated with a certain type of air pollutants called particulate matter, according to a study published in the July 19, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that pollution or amino acids cause dementia, but it suggests a possible link among them.
Published Espresso can prevent Alzheimer's protein clumping in lab tests (via sciencedaily.com)
Whether enjoyed on its own or mixed into a latte, Americano or even a martini, espresso provides an ultra-concentrated jolt of caffeine to coffee lovers. But it might do more than just wake you up. Research now shows that, in preliminary in vitro laboratory tests, espresso compounds can inhibit tau protein aggregation -- a process that is believed to be involved in the onset of Alzheimer's disease.
Published Towards new antibiotics with the first artificial synthesis of tanzawaic acid b (via sciencedaily.com)
Drug-resistant bacteria represent a major threat to public health worldwide, and scientists are constantly searching for novel antibiotic compounds. In a recent study, a research team achieved the first artificial synthesis of tanzawaic acid B, a promising antibiotic drug candidate, on gram scale. Their findings can make synthetic tanzawaic acids widely available, paving the way for the discovery of new drugs.
Published Scientists find that a special omega-3 lipid might prevent fatty liver disease (via sciencedaily.com)
Omega-3 lysolipids are important for protecting the liver from dietary fat, according to researchers.