Showing 20 articles starting at article 1
Published Lab-spun sponges form perfect scaffolds for growing skin cells to heal wounds (via sciencedaily.com) Original source
A new technique for electro-spinning sponges has allowed scientists to directly produce 3D scaffolds -- on which skin grafts could be grown from the patient's own skin.
Published Similarities and differences in human and insect vision formation (via sciencedaily.com) Original source
Researchers have discovered profound similarities and surprising differences between humans and insects in the production of the critical light-absorbing molecule of the retina, 11-cis-retinal, also known as the 'visual chromophore.' The findings deepen understanding of how mutations in the RPE65 enzyme cause retinal diseases, especially Leber congenital amaurosis, a devastating childhood blinding disease.
Published Bridging diet, microbes, and metabolism: Implications for metabolic disorders (via sciencedaily.com) Original source
Mounting evidence suggests that the secret to understanding human health and combating metabolic diseases lies hidden within the microscopic world of our gut bacteria. Recent research reveals that a specific fatty acid produced by gut bacteria directly influences fat metabolism in animals. This research is pivotal as it sheds light on the complex interplay between the diet, gut microbiota, and host metabolic health, offering insights that could open new avenues in our approach to managing metabolic disorders.
Published Eating too much protein is bad for your arteries, and this amino acid is to blame (via sciencedaily.com) Original source
Consuming over 22% of dietary calories from protein can lead to increased activation of immune cells that play a role in atherosclerotic plaque formation and drive the disease risk, new study showed.
Published Link between high levels of niacin -- a common B vitamin -- and heart disease, study suggests (via sciencedaily.com) Original source
Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease. Higher circulating levels of 4PY were strongly associated with development of heart attack, stroke and other adverse cardiac events in large-scale clinical studies. The researchers also showed in preclinical studies that 4PY directly triggers vascular inflammation which damages blood vessels and can lead to atherosclerosis over time.
Published Turning back the clock on photoaging skin (via sciencedaily.com) Original source
A new study examines dermal injections and their impact on skin aging.
Published Wound-homing molecule accelerates tissue repair (via sciencedaily.com) Original source
Medical researchers have found a peptide which, when administered intravenously, homes in on the new blood vessels that are forming in damaged tissue. The peptide has been used as a delivery vehicle for therapeutics targeted at regenerating tissues. A new study has discovered that the peptide activates the natural healing mechanism in the tissue, accelerating regeneration. The finding opens new opportunities to treat not only skin wounds, but also any injuries resulting from accidents and traumas, such as ruptured muscles and fractured bones.
Published Blocking an essential nutrient inhibits malaria parasite growth (via sciencedaily.com) Original source
Researchers found that by preventing the malaria parasite from scavenging fatty acids, a type of required nutrient, it could no longer grow.
Published Non-invasive techniques to detect skin cancer (via sciencedaily.com) Original source
A study has demonstrated that the appearance of ageing skin looks noticeably different compared to younger skin, when examined under polarized laser light. The scientists believe that their new finding could pave the way for new, non-invasive light-based techniques to detect diseases, including cancer, in older individuals. This could significantly enhance early-stage treatment options for various skin conditions.
Published Heart organoids simulate pregestational diabetes-induced congenital heart disease (via sciencedaily.com) Original source
An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. The findings also showed that endoplasmic reticulum (ER) stress and lipid imbalance are critical factors contributing to these disorders, which could be ameliorated with exposure to omega-3s.
Published Doctors have more difficulty diagnosing disease when looking at images of darker skin (via sciencedaily.com) Original source
Doctors do not perform as well diagnosing skin diseases when the patient has darker skin, according to a new study. The researchers found assistance from artificial intelligence could improve doctors' accuracy, but those improvements were greater in patients with lighter skin.
Published Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring (via sciencedaily.com) Original source
New findings report that a class of small RNAs (microRNAs), microRNA-29, can restore normal skin structure rather than producing a wound closure by a connective tissue (scar). Any improvement of normal skin repair would benefit many patients affected by large-area or deep wounds prone to dysfunctional scarring.
Published Archaeological evidence of seasonal vitamin D deficiency discovered (via sciencedaily.com) Original source
Rickets ran rife in children following the Industrial Revolution, but new research has found factory work and polluted cities aren't entirely to blame for the period's vitamin D deficiencies.
Published Sweat-resistant wearable robot sensor (via sciencedaily.com) Original source
A joint research team has developed a stretchable and adhesive microneedle sensor that can be attached to the skin and stably measure high-quality electrophysiological signals for a long period of time.
Published Study could pave the way for better diagnosis of rare genetic diseases (via sciencedaily.com) Original source
Using groundbreaking CRISPR technology, a team of researchers has activated genes in easily accessible cells, which could revolutionize the understanding and diagnosis of genetic diseases.
Published Third major study finds evidence that daily multivitamin supplements improve memory and slow cognitive aging in older adults (via sciencedaily.com) Original source
Researchers tested the effects of a daily multivitamin on cognitive changes in a study of 573 participants with in-person visits in the COSMOS trial. The researchers also conducted a meta-analysis among over 5,000 non-overlapping participants across the three separate cognition studies within the COSMOS trial. Results showed a statistically significant benefit for cognition among participants taking the multi-vitamin compared to placebo, suggesting that a multi-vitamin could help prevent memory loss and slow cognitive aging among older adults.
Published Energy-starved breast cancer cells consume their surroundings for fuel (via sciencedaily.com) Original source
Breast cancer cells ingest and consume the matrix surrounding them to overcome starvation, according to a new study. The finding elucidates a previously unknown mechanism of cancer cell survival, and may offer a new target for therapy development.
Published A novel pathway regulating lipid biosynthesis by fatty acids (via sciencedaily.com) Original source
Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid biosynthesis. Moreover, the team unveiled, for the first time, that the biosynthesis process of fatty acid in the liver is activated by saturated fatty acids and inhibited by polyunsaturated fatty acids, providing new insights into the intricate workings of this cleavage system.
Published New study reveals high prevalence of anemia with low rates of screening (via sciencedaily.com) Original source
A new study has found high rates of anemia among patients in the Irish health system, while screening for common causes was found to be low.
Published Researchers discover potential microbiome links to skin aging (via sciencedaily.com) Original source
Recent findings have identified a potential new link to signs of skin aging -- the skin microbiome, the collection of microorganisms that inhabits our skin.