Published Innovative paper-like, battery-free, AI-enabled sensor for holistic wound monitoring
(via sciencedaily.com) Original source Scientists have invented a paper-like, battery-free, AI-enabled sensor patch -- PETAL -- for convenient and effective monitoring of wound recovery. This novel technology provides early warning of complications to improve wound care. The paper-like, battery-free PETAL sensor patch uses five colorimetric sensors to measure biomarkers in the wound within 15 mins. A proprietary AI algorithm quickly analyses the digital image of the sensor patch to determine wound healing status with an accuracy rate of 97%.
Published Research challenges current thinking on the genetic causes of very early menopause
(via sciencedaily.com) Original source The genetic causes of very early menopause will have to be reconsidered after researchers found that nearly all women who carried variations thought to cause the condition in fact had their menopause at an older age.
Published Study hints at how cancer immunotherapy can be safer
(via sciencedaily.com) Original source Cancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumors. Immunotherapies that block checkpoint receptors like PD-1, proteins that limit the capacity of T cells to attack tumors, have become the choice for the treatment of numerous types of solid cancer. However, the introduction of PD-1-blocking agents can often result in T cells attacking healthy tissues in addition to cancer cells, causing severe, sometimes life-threatening, side effects that can blunt the benefits of immunotherapy. A new study reveals new insights into how PD-1 functions to maintain healthy tissues, findings that can help scientists predict, treat, or even prevent the side effects of PD-1 blocking immunotherapies.
Published New study links contraceptive pills and depression
(via sciencedaily.com) Original source Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. Contraceptive pills increased women's risk by 73 per cent during the first two years of use.
Published The IL-17 protein plays a key role in skin aging
(via sciencedaily.com) Original source A team of scientists has discovered that IL-17 protein plays a central role in skin aging. The study highlights an IL-17-mediated ageing process to an inflammatory state.
Published PAINTing a wound-healing ink into cuts with a 3D-printing pen
(via sciencedaily.com) Original source The body is pretty good at healing itself, though more severe wounds can require bandages or stitches. But researchers have now developed a wound-healing ink that can actively encourage the body to heal by exposing the cut to immune-system vesicles. The ink can be spread into a cut of any shape using a 3D-printing pen, and in mice, the technology nearly completely repaired wounds in just 12 days.
Published New type of drug candidate effectively accelerates wound healing in clinical study
(via sciencedaily.com) Original source Complicated, hard-to-heal wounds are a growing medical problem and there are currently only two drugs approved with proven efficacy. In a new study on humans, researchers show that treatment with a specific type of modified lactic acid bacteria works well and has a positive effect on the healing of wounds.
Published One step closer to developing a potentially ultraprotective sunscreen from our own melanin
(via sciencedaily.com) Original source Researchers have announced a major advance in understanding the fundamental structure of melanin and one of its components that turns light into heat, protecting the body from sun damage.
Published Non-antibiotic treatment for women with persistent acne shown to be effective
(via sciencedaily.com) Original source A team of researchers has shown that a cheap and readily available drug, used to treat high blood pressure, could help the thousands of women who suffer from persistent acne.
Published Researchers reveal an ancient mechanism for wound repair
(via sciencedaily.com) Original source The study is the first to identify a damage response pathway that is distinct from but parallel to the classical pathway triggered by pathogens.
Published Wearable patch can painlessly deliver drugs through the skin
(via sciencedaily.com) Original source A wearable patch applies painless ultrasonic waves to the skin, creating tiny channels that drugs can pass through.
Published Osteoporosis treatments may benefit from discovery of key driver of low bone density
(via sciencedaily.com) Original source Scientists have pinpointed a key driver of low bone density, a discovery that may lead to improved treatments with fewer side effects for women with osteoporosis. The findings reveal that loss of an epigenetic modulator, KDM5C, preserves bone mass in mice. KDM5C works by altering epigenetic 'marks,' which are akin to 'on' and 'off' switches that ensure the instructions written in DNA are used at the right time and in the right place.
Published The wound dressing that can reveal infection
(via sciencedaily.com) Original source A nanocellulose wound dressing that can reveal early signs of infection without interfering with the healing process has been developed.
Published Now you can be comfortable in your e-skin
(via sciencedaily.com) Original source Researchers have designed a cellulose nanofiber paper (nanopaper) that can be used as a substrate for on-skin electronics. The porous structure of the nanopaper means that it can conform and adhere to the skin well enough for effective signal transfer and allows moisture to pass through for breathability and comfort. It is hoped that the nanopaper can soon be used to acquire electrophysiological data, such as ECGs in the clinic.
Published How electricity can heal wounds three times as fast
(via sciencedaily.com) Original source Chronic wounds are a major health problem for diabetic patients and the elderly -- in extreme cases they can even lead to amputation. Using electric stimulation, researchers have developed a method that speeds up the healing process, making wounds heal three times faster.
Published Select cells 'home in on the skin like guided missiles' at birth to enhance immunity
(via sciencedaily.com) Original source Like deployment of an elite fighting team, localization of certain T cells to the skin is important at birth and for lifelong immunity, according to new research.
Published Oral barrier is similar in ceramide composition to skin barrier
(via sciencedaily.com) Original source Acylceramides and protein-bound ceramides are vital for the formation of the oral barrier in mice, similar to their role in skin, protecting from infection.
Published Scientists track evolution of microbes on the skin's surface
(via sciencedaily.com) Original source Researchers have discovered that Staphylococcus aureus can rapidly evolve within a single person's microbiome. They found that in people with eczema, S. aureus tends to evolve to a variant with a mutation in a specific gene that helps it grow faster on the skin.
Published Early menopause, later start to hormone therapy may increase risk of Alzheimer's disease
(via sciencedaily.com) Original source Women are more likely than men to develop Alzheimer's disease (AD), with women making up two-thirds of the population living with AD. A new study sheds light on the relationship between the risk of Alzheimer's disease and age of menopause and use of hormone therapy (HT).
Published Boosting the body's anti-viral immune response may eliminate aging cells
(via sciencedaily.com) Original source Aging cells express a protein that is produced by human cytomegalovirus and is targeted by certain immune cells in the body. Harnessing the immune response to this protein could have multiple health benefits during aging.