Showing 20 articles starting at article 1
Categories: Birth Defects, Pregnancy and Childbirth
Published Human embryo-like models created from stem cells to understand earliest stages of human development
(via sciencedaily.com) Original source Scientists have created a stem cell-derived model of the human embryo in the lab by reprogramming human stem cells. The breakthrough could help research into genetic disorders and in understanding why and how pregnancies fail.
Published One in five women become pregnant naturally after having a baby conceived with IVF
(via sciencedaily.com) Original source New research analyzed data from 11 studies of over 5,000 women around the world between 1980 and 2021, to evaluate how common it is to get pregnant naturally after having a baby conceived by fertility treatment. Around 20% of women who needed fertility treatment, such as IVF, to conceive their first child are likely to get pregnant naturally in the future, finds a new study.
Published What role does alternative splicing play in neurodegenerative disease?
(via sciencedaily.com) Original source Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these disorders.
Published Scientists discover new embryonic cell type that self-destructs to protect the developing embryo
(via sciencedaily.com) Original source Scientists have uncovered a new quality control system that removes damaged cells from early developing embryos.
Published Pregnancy hormone repairs myelin damage in MS mouse model
(via sciencedaily.com) Original source A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
Published Technique restores healthy bacterial balance in C-section babies
(via sciencedaily.com) Original source Newborns delivered by cesarean section who are swabbed with the vaginal fluid of their mothers after birth have beneficial bacteria restored to their skin surface and stools, according to a new study. In the first randomized study of its kind, a team of researchers found the process, known as vaginal seeding, definitively engrafted new strains of maternal bacteria in the babies' bodies.
Published New diagnostic finds intact sperm in infertile men
(via sciencedaily.com) Original source Researchers develop new diagnostic tool to visualize protein biomarkers of well-developed sperm to determine if surgical sperm extraction may be successful for certain infertile men.
Published Exposure to 'forever chemicals' during pregnancy linked to increased risk of obesity in kids
(via sciencedaily.com) Original source Exposure to per- and polyfluoroalkyl substances (PFAS) during pregnancy was linked to slightly higher body mass indices and an increased risk of obesity in children, according to a new study.
Published Poorly insulated nerve cells promote Alzheimer's disease in old age
(via sciencedaily.com) Original source Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
Published Open-analysis platform for pediatric brain tumors provides robust data resource for childhood cancer research
(via sciencedaily.com) Original source Researchers have partnered to create a first-of-its-kind open-source, reproducible analysis platform for pediatric brain tumors. With the help of thousands of genomically sequenced samples, researchers have used this platform to identify initial findings about genetic variants associated with poorer outcomes that could help guide future diagnostic and therapeutic advances.
Published Scientists unveil RNA-guided mechanisms driving cell fate
(via sciencedaily.com) Original source The early stages of embryonic development contain many of life's mysteries. Unlocking these mysteries can help us better understand early development and birth defects, and help develop new regenerative medicine treatments. Researchers have now characterized a critical time in mammalian embryonic development using powerful and innovative imaging techniques.
Published Understanding the speed of brain communication
(via sciencedaily.com) Original source Called the human connectome, this structural system of neural pathways develops as people age. A new study shows transmission speed among brain regions increases into early adulthood. Learning more about neuron transmission may improve the understanding of psychological disorders.
Published A special omega-3 fatty acid lipid will change how we look at the developing and aging brain
(via sciencedaily.com) Original source Scientists have found a lipid transporter crucial to regulating the cells that make myelin, the nerve-protecting sheath.
Published Gene responsible for severe facial defects identified
(via sciencedaily.com) Original source Goldenhar syndrome is a rare congenital disease, affecting early fetal development. This syndrome includes malformations of varying severity, affecting different parts of the face. Its causes and modes of transmission are still poorly understood. An international collaboration has discovered that pathogenic variants of the FOXI3 gene -- responsible for the development of the ear -- cause one form of this developmental disorder. The scientists were also able to identify the modes of transmission of the disease when this particular gene is involved.
Published Labor induction doesn't always reduce Caesarean birth risk or improve outcomes for term pregnancies
(via sciencedaily.com) Original source Findings conflict with previous national trial results: Women who underwent elective induction were more likely to have a cesarean birth compared with those who underwent expectant management (30% versus 24%.)
Published Problems with 'pruning' brain connections linked to adolescent mental health disorders
(via sciencedaily.com) Original source Problems with the brain's ability to 'prune' itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence, according to research published today. The findings may help explain why people are often affected by more than one mental health disorder, and may in future help identify those at greatest risk.
Published How alcohol consumption contributes to chronic pain
(via sciencedaily.com) Original source A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.
Published A gene involved in Down syndrome puts the brakes on neurons' activity in mice
(via sciencedaily.com) Original source Researchers have found that an extra copy of a gene in Down syndrome patients causes improper development of neurons in mice.
Published Impact of maternal stress during pregnancy on child's health
(via sciencedaily.com) Original source New research examines the impact that maternal stress during pregnancy has on the neuro-development of babies.
Published Drinking alcohol while breastfeeding impacts health of newborns
(via sciencedaily.com) Original source What are the consequences of mothers consuming alcohol while breastfeeding? A research team at the University of California, Riverside, performed a mouse study to find out.