Published Skin behind the ears and between the toes can host a collection of unhealthy microbes
(via sciencedaily.com) Scrubbing behind the ears and between the toes may help keep the skin in those regions healthy, new research suggests. The microbiome, or the collection of microbes living on and in the human body, are known to play a role in human health and the skin is no different. A new study has shown that the composition of the skin microbiome varies across dry, moist and oily regions of the skin.
Published Clinical trial recommends methotrexate for children with severe atopic dermatitis
(via sciencedaily.com) Findings from a clinical trial has recommended methotrexate for children with severe atopic dermatitis.
Published Inflammatory bowel disease linked to atopic dermatitis
(via sciencedaily.com) Adults with atopic dermatitis (AD) have a 34 percent increased risk of developing new-onset inflammatory bowel disease (IBD) compared with individuals who do not have the skin condition, and children have a 44 percent increased risk, according to a new study.
Published Tiny nanocarriers could prove the magic bullet for acne sufferers
(via sciencedaily.com) It's a skin disorder that makes life miserable for around 800 million teenagers and adults worldwide, but cientists may have found an effective treatment for acne, delivered via tiny nanoparticles.
Published Breakthrough in scarless wound recovery achieved with autologous blood
(via sciencedaily.com) A recent study has introduced a groundbreaking milestone in tissue regeneration by developing a technology that utilizes autologous blood to produce three-dimensional microvascular implants.
Published New insights into melanoma development and therapy
(via sciencedaily.com) Researchers have revealed that the expression of a specific isoform of GREB1 Is4 is induced in malignant melanoma cells by the melanocyte-specific transcription factor, MITF. They revealed that GREB1 Is4 stimulates pyrimidine biosynthesis and promotes cancer cell proliferation. Furthermore, the anti-tumor effect of antisense nucleic acids against GREB1 showed a potential new modality for malignant melanoma.
Published Why men, wealthy people and maritime residents are more likely to develop skin cancer
(via sciencedaily.com) A new study examines why people living in Atlantic regions are more at-risk for developing melanoma than other Canadians, providing lessons on skin cancer prevention for the whole country. To find out why, the researchers compared UV exposure and behaviours among different groups in Atlantic Canada based on income, education, and gender, among other factors.
Published Time is right to develop a consensus Human Skin Cell Atlas, according to leading dermatology experts
(via sciencedaily.com) As a single organ, our skin is able to perform a broad repertoire of vital functions. Dermatology experts call for a reference guide to single-cell composition of normal human skin, which is still lacking. A grassroots movement to establish a Human Skin Cell Atlas is taking shape, as reported in a recent review. A global team of experts has outlined a roadmap as a first step towards creating a comprehensive and inclusive reference work on this important topic.
Published Protein found in milk speeds up wound healing
(via sciencedaily.com) Bandages infused with casein, a protein that occurs naturally in cow's milk, significantly improved wound healing in rats compared to those in control groups, according to a new study by researchers.
Published Why does skin get 'leathery' after too much sun? Bioengineers examine cellular breakdown
(via sciencedaily.com) A study explores how ultraviolet radiation can alter the microstructure of human skin. Particularly affected is collagen, the fibrous protein that binds together tissue, tendon, cartilage and bone throughout our bodies.
Published Clinical trial to help millions with penicillin allergies
(via sciencedaily.com) Original source Many low-risk patients with a penicillin allergy were able to have their penicillin allergy label removed through a simple procedure known as 'direct oral challenge' as part of a world-first multicenter randomized control trial known as the Penicillin Allergy Clinical Decision Rule (PALACE) study.
Published Breakthrough treatment for skin infection: Novel microneedle array embedded with ultrasound-triggered antibacterial nanoparticles
(via sciencedaily.com) Original source A research team has designed a new microneedle patch to offer a highly-effective non-antibiotic approach for the treatment of skin infection. In brief, the design engineered with ultrasound-responsive zinc-based metal-organic framework (MOF) antibacterial nanoparticles promises pain-free delivery to treat bacterial infection on skin tissue and facilitate skin repair at the same time. The novel microneedle is around 50 microns in diameter, similar to a typical hair.
Published DNA barcoding identifies the plants a person has eaten
(via sciencedaily.com) Original source DNA barcoding is now being used to identify the plant matter in human feces, revealing what a person has eaten. A reliable genetic marker for plant-based foods can be retrieved from poop, showing not only what was eaten, but in what relative amounts. The technique should improve clinical trials, nutrition studies and more.
Published Unsafe feeding methods spiked during infant formula shortage
(via sciencedaily.com) Original source A survey finds nearly half of parents who rely on formula for their babies resorted to potentially harmful feeding methods during the infant formula shortage.
Published Molecular imaging identifies brain changes in response to food cues; offers insight into obesity interventions
(via sciencedaily.com) Original source Molecular imaging with 18F-flubatine PET/MRI has shown that neuroreceptors in the brains of individuals with obesity respond differently to food cues than those in normal-weight individuals, making the neuroreceptors a prime target for obesity treatments and therapy. This research contributes to the understanding of the fundamental mechanisms underlying obesity and offers valuable insights into potential medical interventions.
Published Innovative paper-like, battery-free, AI-enabled sensor for holistic wound monitoring
(via sciencedaily.com) Original source Scientists have invented a paper-like, battery-free, AI-enabled sensor patch -- PETAL -- for convenient and effective monitoring of wound recovery. This novel technology provides early warning of complications to improve wound care. The paper-like, battery-free PETAL sensor patch uses five colorimetric sensors to measure biomarkers in the wound within 15 mins. A proprietary AI algorithm quickly analyses the digital image of the sensor patch to determine wound healing status with an accuracy rate of 97%.
Published Lean body mass, age linked with alcohol elimination rates in women
(via sciencedaily.com) Original source Research links women's lean body mass with how quickly they eliminate alcohol from their system. Women with obesity and those who are older eliminate alcohol from their bloodstreams faster than those of normal weight and those who are younger.
Published All the immunity, none of the symptoms
(via sciencedaily.com) Original source Scientists found pairing specific diets with diarrheal disease-causing bacteria can create lasting immunity in mice without a need to ever experience symptoms. The findings pave the way for vaccine development that could reduce symptoms and mortality of diarrheal illness and other diseases in humans.
Published Omega-3 fatty acids linked to slower decline in ALS
(via sciencedaily.com) Original source People with amyotrophic lateral sclerosis (ALS) who eat more foods high in certain omega-3 fatty acids like flaxseed oil, walnuts, canola oil and pumpkin seeds may have a slower physical decline from the disease and may have a slightly extended survival. Researchers also found an omega-6 fatty acid may be beneficial. The study does not prove that these omega fatty acids slow decline of ALS or extend survival; it only shows an association.
Published Study hints at how cancer immunotherapy can be safer
(via sciencedaily.com) Original source Cancer immunotherapy has revolutionized treatment of many forms of cancer by unleashing the immune system response against tumors. Immunotherapies that block checkpoint receptors like PD-1, proteins that limit the capacity of T cells to attack tumors, have become the choice for the treatment of numerous types of solid cancer. However, the introduction of PD-1-blocking agents can often result in T cells attacking healthy tissues in addition to cancer cells, causing severe, sometimes life-threatening, side effects that can blunt the benefits of immunotherapy. A new study reveals new insights into how PD-1 functions to maintain healthy tissues, findings that can help scientists predict, treat, or even prevent the side effects of PD-1 blocking immunotherapies.