Showing 20 articles starting at article 1
Categories: Healthy Aging, Schizophrenia
Published Scientists take next big step in understanding genetics of schizophrenia
(via sciencedaily.com) Original source Scientists are figuring out which of the 5,000 variants associated with schizophrenia have an actual causal effect in the development of the condition that affects millions of people worldwide.
Published Schizophrenia genetic risk factor impairs mitochondrial function
(via sciencedaily.com) Original source Researcher discovers possible link of mitochondrial function to the development of schizophrenia.
Published New neuroimaging approach could improve diagnosis of schizophrenia
(via sciencedaily.com) Original source New research has identified age-related changes in brain patterns associated with the risk for developing schizophrenia. The discovery could help clinicians identify the risk for developing mental illness earlier and improve treatment options.
Published Schizophrenia is associated with somatic mutations occurring in utero
(via sciencedaily.com) Original source As a psychiatric disorder with onset in adulthood, schizophrenia is thought to be triggered by some combination of environmental factors and genetics, although the exact cause is still not fully understood. Researchers have now found a correlation between schizophrenia and somatic copy-number variants, a type of mutation that occurs early in development but after genetic material is inherited. This study is one of the first to rigorously describe the relationship between somatic -- not inherited -- genetic mutations and schizophrenia risk.
Published Follow the leader: Researchers identify mechanism of cancer invasion
(via sciencedaily.com) Original source A cancerous tumor is the accumulation of cells uncontrollably dividing, some of which can invade other parts of the body. The process is difficult to predict in detail, and eradicating the cells poses even greater difficulty. Now, a research team has revealed how the exodus initiates, shedding light on a potential therapeutic target to halt the invasion and providing a prognostic marker to help clinicians select the best treatment option.
Published Poor sense of smell linked to increased risk of depression in older adults
(via sciencedaily.com) Original source In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.
Published Pain not perceived in the same way in people with Alzheimer's Disease
(via sciencedaily.com) Original source New research has found that in a mouse model mimicking Alzheimer's Disease (AD) pain signals are not processed in the same way as in healthy mice.
Published Loss of Y chromosome in men enables cancer to grow
(via sciencedaily.com) Original source As men age, some of their cells lose the very thing that makes them biological males -- the Y chromosome -- and this loss hampers the body's ability to fight cancer, according to new research. The study found that loss of the Y chromosome helps cancer cells evade the body's immune system. This common impact of the aging process in men results in aggressive bladder cancer, but somehow also renders the disease more vulnerable -- and responsive -- to a standard treatment called immune checkpoint inhibitors.
Published New findings show mitochondrial DNA fragments in blood as important biomarkers for aging and inflammation
(via sciencedaily.com) Original source In an eight-year study of more than 600 community-dwelling older adults, researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty. The study is novel and expands on previous work, the investigators say, because it focused on mitochondrial DNA rather than solely genomic DNA, as previously reported.
Published Close up on aging reveals how different cell types in the body age at different pace
(via sciencedaily.com) Original source A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Published Ultra small molecule as a new target for Alzheimer's disease?
(via sciencedaily.com) Original source A new study shows that a very small molecule called microRNA-132 can have a significant impact on different brain cells and may play a role in Alzheimer's disease.
Published Altered gut bacteria may be early sign of Alzheimer's disease
(via sciencedaily.com) Original source Alzheimer's disease causes changes to the brain that begin two decades or more before symptoms appear. A study reveals that the bacteria that live in the gut also change before Alzheimer's symptoms arise, a discovery that could lead to diagnostics or treatments for Alzheimer's disease that target the gut microbiome.
Published Taurine may be a key to longer and healthier life
(via sciencedaily.com) Original source A study finds that deficiency of taurine, a molecule produced in our bodies, drives aging, and taurine supplements can improve health and increase lifespan in animals.
Published The IL-17 protein plays a key role in skin aging
(via sciencedaily.com) Original source A team of scientists has discovered that IL-17 protein plays a central role in skin aging. The study highlights an IL-17-mediated ageing process to an inflammatory state.
Published A chance observation finds potential hearing biomarker for Alzheimer's disease
(via sciencedaily.com) Original source Researchers found where plaques are found in the brain may impact hearing in Alzheimer's disease.
Published Sea cucumbers: The marine delicacy that can deter diabetes
(via sciencedaily.com) Original source They're a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research.
Published How does dopamine regulate both learning and motivation?
(via sciencedaily.com) Original source A new study brings together two schools of thought on the function of the neurotransmitter dopamine: one saying that dopamine provides a learning signal, the other saying that dopamine drives motivation.
Published Poorly insulated nerve cells promote Alzheimer's disease in old age
(via sciencedaily.com) Original source Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
Published Why do some people live to be 100? Intestinal bacteria may hold the answer
(via sciencedaily.com) Original source Some people live longer than others -- possibly due to a unique combination of bacteria in their intestines, new research concludes.
Published Further link identified between autoimmunity and schizophrenia
(via sciencedaily.com) Original source Links have been reported between schizophrenia and proteins produced by the immune system that can act against one's own body, known as autoantibodies. Researchers have now identified autoantibodies that target a 'synaptic adhesion protein' in a subset of patients with schizophrenia. When injected into mice, the autoantibodies caused many schizophrenia-related changes.