Showing 20 articles starting at article 1
Categories: Healthy Aging, Psychology Research
Published Follow the leader: Researchers identify mechanism of cancer invasion



A cancerous tumor is the accumulation of cells uncontrollably dividing, some of which can invade other parts of the body. The process is difficult to predict in detail, and eradicating the cells poses even greater difficulty. Now, a research team has revealed how the exodus initiates, shedding light on a potential therapeutic target to halt the invasion and providing a prognostic marker to help clinicians select the best treatment option.
Published Poor sense of smell linked to increased risk of depression in older adults



In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.
Published A subtype of depression identified



Using surveys, cognitive tests and brain imaging, researchers have identified a type of depression that affects about a quarter of patients. The goal is to diagnose and treat the condition more precisely.
Published Chronic stress-related neurons identified



Researchers have identified a group of nerve cells in the mouse brain that are involved in creating negative emotional states and chronic stress. The neurons, which have been mapped with a combination of advanced techniques, also have receptors for estrogen, which could explain why women as a group are more sensitive to stress than men.
Published Pain not perceived in the same way in people with Alzheimer's Disease



New research has found that in a mouse model mimicking Alzheimer's Disease (AD) pain signals are not processed in the same way as in healthy mice.
Published Studying herpes encephalitis with mini-brains



The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists.
Published Unraveling the connections between the brain and gut



Engineers designed a technology to probe connections between the brain and the digestive tract. Using fibers embedded with a variety of sensors, as well as optogenetic stimulation, the researchers could control neural circuits connecting the gut and the brain, in mice.
Published Loss of Y chromosome in men enables cancer to grow



As men age, some of their cells lose the very thing that makes them biological males -- the Y chromosome -- and this loss hampers the body's ability to fight cancer, according to new research. The study found that loss of the Y chromosome helps cancer cells evade the body's immune system. This common impact of the aging process in men results in aggressive bladder cancer, but somehow also renders the disease more vulnerable -- and responsive -- to a standard treatment called immune checkpoint inhibitors.
Published New findings show mitochondrial DNA fragments in blood as important biomarkers for aging and inflammation



In an eight-year study of more than 600 community-dwelling older adults, researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty. The study is novel and expands on previous work, the investigators say, because it focused on mitochondrial DNA rather than solely genomic DNA, as previously reported.
Published Restoring the blood-brain barrier?



Scientists discover a treatment in mice to repair the blood-brain barrier, which is key to brain health.
Published Everyone's brain has a pain fingerprint -- new research has revealed for the first time



New research has revealed everyone's brain has a 'pain fingerprint' that varies from person to person.
Published Brain receptor patterns separate sensory and cognitive networks



Receptor patterns define key organizational principles in the brain, scientists have discovered.
Published Scientists discover spiral-shaped signals that organize brain activity



Scientists have discovered human brain signals traveling across the outer layer of neural tissue that naturally arrange themselves to resemble swirling spirals.
Published Astrocyte processing of serotonin regulates olfactory perception



Researchers have uncovered novel aspects of astrocyte function in olfactory, or smell, perception revealing changes in their gene expression patterns that turn these brain cells into a hub of olfactory sensation processing.
Published Close up on aging reveals how different cell types in the body age at different pace



A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Published Pregnancy hormone repairs myelin damage in MS mouse model



A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
Published New discovery can help detect brain tumors



Folate-based radiopharmaceuticals can be used in positron emission tomography (PET) imaging to detect folate receptors in brain tumours. The discovery of folate receptors and their exploitation potential with respect to brain tumours is a new and significant finding in the field.
Published Ultra small molecule as a new target for Alzheimer's disease?



A new study shows that a very small molecule called microRNA-132 can have a significant impact on different brain cells and may play a role in Alzheimer's disease.
Published Video games spark exciting new frontier in neuroscience



Researchers have used an algorithm from a video game to gain insights into the behavior of molecules within live brain cells. Researchers used coding tools to build an algorithm that is now used by several labs to gather rich data about brain cell activity. The algorithm was applied to observe molecules clustering together -- which ones, when, where, for how long and how often.
Published AI helps show how the brain's fluids flow



A new, AI-based technique for measuring fluid flow in the brain could lead to treatments for diseases such as Alzheimer's.