Showing 20 articles starting at article 1
Published Follow the leader: Researchers identify mechanism of cancer invasion (via sciencedaily.com) Original source
A cancerous tumor is the accumulation of cells uncontrollably dividing, some of which can invade other parts of the body. The process is difficult to predict in detail, and eradicating the cells poses even greater difficulty. Now, a research team has revealed how the exodus initiates, shedding light on a potential therapeutic target to halt the invasion and providing a prognostic marker to help clinicians select the best treatment option.
Published Poor sense of smell linked to increased risk of depression in older adults (via sciencedaily.com) Original source
In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.
Published Study sets new standard for graft-versus-host disease prevention after stem cell transplant (via sciencedaily.com) Original source
Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study. The new standard is more effective at preventing GVHD and came with less side effects, compared with the current gold standard.
Published Pain not perceived in the same way in people with Alzheimer's Disease (via sciencedaily.com) Original source
New research has found that in a mouse model mimicking Alzheimer's Disease (AD) pain signals are not processed in the same way as in healthy mice.
Published Omega-3 fatty acids linked to slower decline in ALS (via sciencedaily.com) Original source
People with amyotrophic lateral sclerosis (ALS) who eat more foods high in certain omega-3 fatty acids like flaxseed oil, walnuts, canola oil and pumpkin seeds may have a slower physical decline from the disease and may have a slightly extended survival. Researchers also found an omega-6 fatty acid may be beneficial. The study does not prove that these omega fatty acids slow decline of ALS or extend survival; it only shows an association.
Published Loss of Y chromosome in men enables cancer to grow (via sciencedaily.com) Original source
As men age, some of their cells lose the very thing that makes them biological males -- the Y chromosome -- and this loss hampers the body's ability to fight cancer, according to new research. The study found that loss of the Y chromosome helps cancer cells evade the body's immune system. This common impact of the aging process in men results in aggressive bladder cancer, but somehow also renders the disease more vulnerable -- and responsive -- to a standard treatment called immune checkpoint inhibitors.
Published Blood pressure drug could prevent post-traumatic headaches (via sciencedaily.com) Original source
A study has shown that prazosin, a drug used to treat high blood pressure, can prevent post-traumatic headaches.
Published New findings show mitochondrial DNA fragments in blood as important biomarkers for aging and inflammation (via sciencedaily.com) Original source
In an eight-year study of more than 600 community-dwelling older adults, researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty. The study is novel and expands on previous work, the investigators say, because it focused on mitochondrial DNA rather than solely genomic DNA, as previously reported.
Published What role does alternative splicing play in neurodegenerative disease? (via sciencedaily.com) Original source
Scientists have written a review to discuss emerging research and evidence of the roles of alternative splicing defects in major neurodegenerative diseases. They also summarize the latest advances in RNA-based therapeutic strategies to target these disorders.
Published Close up on aging reveals how different cell types in the body age at different pace (via sciencedaily.com) Original source
A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Published Ultra small molecule as a new target for Alzheimer's disease? (via sciencedaily.com) Original source
A new study shows that a very small molecule called microRNA-132 can have a significant impact on different brain cells and may play a role in Alzheimer's disease.
Published Altered gut bacteria may be early sign of Alzheimer's disease (via sciencedaily.com) Original source
Alzheimer's disease causes changes to the brain that begin two decades or more before symptoms appear. A study reveals that the bacteria that live in the gut also change before Alzheimer's symptoms arise, a discovery that could lead to diagnostics or treatments for Alzheimer's disease that target the gut microbiome.
Published Researchers uncover why light-to-moderate drinking is tied to better heart health (via sciencedaily.com) Original source
A new study offers an explanation for why light-to-moderate alcohol consumption may be associated with lower risk of heart disease. For the first time, researchers found that alcohol, in light to moderate quantities, was associated with long-term reductions in stress signaling in the brain.
Published New study links contraceptive pills and depression (via sciencedaily.com) Original source
Women who used combined contraceptive pills were at greater risk of developing depression than women who did not, according to a new study. Contraceptive pills increased women's risk by 73 per cent during the first two years of use.
Published New research identifies cells linking chronic psychological stress to inflammatory bowel disease (via sciencedaily.com) Original source
For the first time, cells involved with the communication between stress responses in the brain and inflammation in the gastrointestinal (GI) tract have been identified in animal models. Glial cells, which support neurons, communicate stress signals from the central nervous system (CNS) to the semi-autonomous nervous system within the gastrointestinal (GI) tract, called the enteric nervous system (ENS). These psychological stress signals can cause inflammation and exacerbate symptoms of inflammatory bowel disease (IBD).
Published Taurine may be a key to longer and healthier life (via sciencedaily.com) Original source
A study finds that deficiency of taurine, a molecule produced in our bodies, drives aging, and taurine supplements can improve health and increase lifespan in animals.
Published The IL-17 protein plays a key role in skin aging (via sciencedaily.com) Original source
A team of scientists has discovered that IL-17 protein plays a central role in skin aging. The study highlights an IL-17-mediated ageing process to an inflammatory state.
Published A chance observation finds potential hearing biomarker for Alzheimer's disease (via sciencedaily.com) Original source
Researchers found where plaques are found in the brain may impact hearing in Alzheimer's disease.
Published Sea cucumbers: The marine delicacy that can deter diabetes (via sciencedaily.com) Original source
They're a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research.
Published Poorly insulated nerve cells promote Alzheimer's disease in old age (via sciencedaily.com) Original source
Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.