Showing 20 articles starting at article 1
Published Lowering a form of brain cholesterol reduces Alzheimer's-like damage in mice (via sciencedaily.com) Original source
Researchers have found that a form of cholesterol known as cholesteryl esters builds up in the brains of mice with Alzheimer's-like disease, and that clearing out the cholesteryl esters helps prevent brain damage and behavioral changes.
Published Mice eating less of specific amino acid -- overrepresented in diet of obese people -- live longer, healthier (via sciencedaily.com) Original source
A new study in mice shows that cutting down the amount of a single amino acid called isoleucine can, among other benefits, extend their lifespan, make them leaner and less frail as they age and reduce cancer and prostate problems, all while the mice ate more calories.
Published From the first bite, our sense of taste helps pace our eating (via sciencedaily.com) Original source
When you eagerly dig into a long-awaited dinner, signals from your stomach to your brain keep you from eating so much you'll regret it -- or so it's been thought.
Published Ultra-processed foods and higher risk of mouth, throat and esophagus cancers (via sciencedaily.com) Original source
Eating more ultra-processed foods (UPFs) may be associated with a higher risk of developing cancers of upper aerodigestive tract (including the mouth, throat and esophagus), according to a new study. The authors of this international study, which analyzed diet and lifestyle data on 450,111 adults who were followed for approximately 14 years, say obesity associated with the consumption of UPFs may not be the only factor to blame.
Published Microautophagy is essential for preventing aging (via sciencedaily.com) Original source
Researchers have shown that lysosomes, key organelles for maintaining cellular stability, can be repaired once damaged by a process termed microautophagy. They identified molecules called STK38 and GABARAPs as key regulators of this process. Depletion of microautophagy regulators lead to increased cellular senescence and a shorter lifespan, indicating the importance of this process. This study is highly significant for the achievement of healthy aging and points toward new therapies for age-related diseases.
Published Hearing loss is associated with subtle changes in the brain (via sciencedaily.com) Original source
A team of researchers employed hearing tests and magnetic resonance imaging (MRI) to determine whether hearing impairment is associated with differences in specific brain regions and affects dementia risk.
Published Could eating turkey ease colitis? (via sciencedaily.com) Original source
According to data in mice, extra tryptophan could reduce the risk of future colitis flares.
Published Coffee grounds may hold key to preventing neurodegenerative diseases (via sciencedaily.com) Original source
A team of researchers found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.
Published Poor work performance among Japanese employees strongly associated with insufficient sleep (via sciencedaily.com) Original source
This study examined the association between work performance and lifestyle habits among Japanese employees. The results revealed that insufficient sleep was the predominant factor affecting work performance in men and women, followed by lack of regular exercise and eating late-evening meals. Furthermore, the study indicated that men were more likely to exhibit lifestyle habits that impacted work performance than women.
Published Feeding dogs raw meat increases the risk of antibiotic-resistant E. coli (via sciencedaily.com) Original source
Feeding dogs raw (uncooked) meat increases their risk of excreting E. coli that cannot be killed by a widely used antibiotic -- ciprofloxacin -- researchers have found from a study of 600 healthy pet dogs.
Published Following a Mediterranean diet reduces the risk of cognitive decline in older people (via sciencedaily.com) Original source
Old people who follow a Mediterranean diet are at a lower risk of cognitive decline, according to a new study. The study provides new evidence for a better understanding of the biological mechanisms related to the impact of the diet on cognitive health in the aging population.
Published Lab-grown 'small blood vessels' point to potential treatment for major cause of stroke and vascular dementia (via sciencedaily.com) Original source
Scientists have grown small blood vessel-like models in the lab and used them to show how damage to the scaffolding that supports these vessels can cause them to leak, leading to conditions such as vascular dementia and stroke.
Published Breakthrough in bladder cancer research (via sciencedaily.com) Original source
For 40 years, chemotherapy has been the standard treatment for bladder cancer patients who can tolerate this medicine. However, the results were limited, and lasting results were rare. In recent years, two groundbreaking phase-3 clinical studies have focused on a new form of treatment to improve this. They investigated the effects of combining immunotherapy and chemotherapy.
Published Study reveals broader impact of Alzheimer's on brain function (via sciencedaily.com) Original source
Scientists have published new evidence that shows changes in brain network patterns that occur in early-stage Alzheimer's disease differ from those associated with normal aging. The findings also show that the impact of Alzheimer's on brain function is broader than previously believed. In addition to detecting characteristic changes in the brain circuits supporting memory and attention as expected, the researchers found distinct changes in circuits involved in sensory and motor processing.
Published Smaller hippocampus linked to cognitive decline (via sciencedaily.com) Original source
With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer's disease or another neurodegenerative disorder. A new study shows that shrinkage in the hippocampus area of the brain is associated with cognitive decline, even in people who don't have amyloid plaques in the brain. The hippocampus plays a role in memory.
Published People with obesity burn less energy during day (via sciencedaily.com) Original source
A study found people who have a healthy weight use more energy during the day, when most people are active and eat, while those who have obesity spend more energy during the night, when most people sleep. Researchers also found that, during the day, those with obesity have higher levels of the hormone insulin -- a sign that the body is working harder to use glucose, an energy-packed sugar.
Published NHS Diabetes Prevention Programme may have global impact (via sciencedaily.com) Original source
As ten percent of the world's adult population is predicted to have diabetes by 2030, a major new study finds that the NHS Diabetes Prevention Programme has a positive effect on reducing risk of developing diabetes.
Published Cycle of fasting and feeding is crucial for healthy aging (via sciencedaily.com) Original source
Fasting interventions, which involve alternating periods of fasting and refeeding, are generally thought to improve health. But these interventions don't work as well in old animals. The question is: Why? By studying the short-lived killifish, researchers have shown that older fish deviate from a youthful fasting and refeeding cycle, and instead enter a state of perpetual fasting, even when ingesting food. However, the benefits of refeeding after fasting in old killifish can be restored by genetically activating a specific subunit of AMP kinase, an important sensor of cellular energy. These mutant fish experienced improved health and longevity, indicating that both fasting and refeeding are needed to confer health benefits and act through AMP kinase to do so.
Published Semaglutide reduced cardiovascular events by 20% in certain adults (via sciencedaily.com) Original source
Semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes, according to new research. Semaglutide is primarily prescribed for adults with type 2 diabetes but is also approved for chronic weight management in adults with obesity or overweight and have at least one other health issue. In the trial, patients treated with semaglutide lost an average of 9.4% of their body weight and experienced improvements in other risk factors for cardiovascular disease. Results from the 'SELECT -- Semaglutide and Cardiovascular Outcomes in Patients with Overweight or Obesity Who Do Not Have Diabetes' trial were presented today during a late-breaking science session at the American Heart Association's Scientific Sessions 2023 and simultaneously published in the New England Journal of Medicine.
Published Cut salt, cut blood pressure (via sciencedaily.com) Original source
Nearly everyone can lower their blood pressure, even people currently on blood pressure-reducing drugs, by lowering their sodium intake, reports a new study. It found 70-75% of all people, regardless of whether they are already on blood pressure medications or not, are likely to see a reduction in their blood pressure if they lower the sodium in their diet. Losing one teaspoon of salt a day results in systolic blood pressure decline comparable to effect achieved with drugs.