Showing 20 articles starting at article 1
Published Discrimination during pregnancy can affect infant's brain circuitry (via sciencedaily.com) Original source
Experiences of discrimination and acculturation are known to have a detrimental effect on a person's health. For pregnant women, these painful experiences can also affect the brain circuitry of their children, a new study finds. These effects, the researchers say, are separate from those caused by general stress and depression. The study was published in the journal Neuropsychopharmacology.
Published Spike in premature births caused by COVID, halted by vaccines, study finds (via sciencedaily.com) Original source
COVID-19 caused an alarming surge in premature births, but vaccines were key to returning the early birth rate to pre-pandemic levels, according to a new analysis of California birth records.
Published Lowering a form of brain cholesterol reduces Alzheimer's-like damage in mice (via sciencedaily.com) Original source
Researchers have found that a form of cholesterol known as cholesteryl esters builds up in the brains of mice with Alzheimer's-like disease, and that clearing out the cholesteryl esters helps prevent brain damage and behavioral changes.
Published Mice eating less of specific amino acid -- overrepresented in diet of obese people -- live longer, healthier (via sciencedaily.com) Original source
A new study in mice shows that cutting down the amount of a single amino acid called isoleucine can, among other benefits, extend their lifespan, make them leaner and less frail as they age and reduce cancer and prostate problems, all while the mice ate more calories.
Published Microautophagy is essential for preventing aging (via sciencedaily.com) Original source
Researchers have shown that lysosomes, key organelles for maintaining cellular stability, can be repaired once damaged by a process termed microautophagy. They identified molecules called STK38 and GABARAPs as key regulators of this process. Depletion of microautophagy regulators lead to increased cellular senescence and a shorter lifespan, indicating the importance of this process. This study is highly significant for the achievement of healthy aging and points toward new therapies for age-related diseases.
Published Hearing loss is associated with subtle changes in the brain (via sciencedaily.com) Original source
A team of researchers employed hearing tests and magnetic resonance imaging (MRI) to determine whether hearing impairment is associated with differences in specific brain regions and affects dementia risk.
Published Coffee grounds may hold key to preventing neurodegenerative diseases (via sciencedaily.com) Original source
A team of researchers found that caffeic-acid based Carbon Quantum Dots (CACQDs), which can be derived from spent coffee grounds, have the potential to protect brain cells from the damage caused by several neurodegenerative diseases.
Published Poor work performance among Japanese employees strongly associated with insufficient sleep (via sciencedaily.com) Original source
This study examined the association between work performance and lifestyle habits among Japanese employees. The results revealed that insufficient sleep was the predominant factor affecting work performance in men and women, followed by lack of regular exercise and eating late-evening meals. Furthermore, the study indicated that men were more likely to exhibit lifestyle habits that impacted work performance than women.
Published Lab-grown 'small blood vessels' point to potential treatment for major cause of stroke and vascular dementia (via sciencedaily.com) Original source
Scientists have grown small blood vessel-like models in the lab and used them to show how damage to the scaffolding that supports these vessels can cause them to leak, leading to conditions such as vascular dementia and stroke.
Published Wearables capture body sounds to continuously monitor health (via sciencedaily.com) Original source
From heart beats to stomach gurgles, sounds hold important health information. New wireless devices sit on skin to continuously capture these sounds, then stream data to smartphones or tablets in real time. In pilot studies, devices accurately tracked sounds associated with cardiorespiratory function, gastrointestinal activity, swallowing and respiration. The devices are particularly valuable for premature babies, who can experience apneas and gastrointestinal complications, which are accompanied by sounds.
Published Breakthrough in bladder cancer research (via sciencedaily.com) Original source
For 40 years, chemotherapy has been the standard treatment for bladder cancer patients who can tolerate this medicine. However, the results were limited, and lasting results were rare. In recent years, two groundbreaking phase-3 clinical studies have focused on a new form of treatment to improve this. They investigated the effects of combining immunotherapy and chemotherapy.
Published Study reveals broader impact of Alzheimer's on brain function (via sciencedaily.com) Original source
Scientists have published new evidence that shows changes in brain network patterns that occur in early-stage Alzheimer's disease differ from those associated with normal aging. The findings also show that the impact of Alzheimer's on brain function is broader than previously believed. In addition to detecting characteristic changes in the brain circuits supporting memory and attention as expected, the researchers found distinct changes in circuits involved in sensory and motor processing.
Published Smaller hippocampus linked to cognitive decline (via sciencedaily.com) Original source
With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer's disease or another neurodegenerative disorder. A new study shows that shrinkage in the hippocampus area of the brain is associated with cognitive decline, even in people who don't have amyloid plaques in the brain. The hippocampus plays a role in memory.
Published Exposure to air pollution in utero may affect reproductive system development (via sciencedaily.com) Original source
From invisible wafts of diesel exhaust to sun-choking plumes of orange smoke, air pollution is known to damage respiratory well-being. Now, research suggests another reason to hold our breath: Polluted air also may hurt reproductive health. In a study of air pollution data in relation to markers of reproductive development in infancy, Rutgers researchers found certain pollutants may negatively alter anogenital distance, a measure of prenatal exposure to hormones.
Published Delaying cord clamping could halve risk of death in premature babies (via sciencedaily.com) Original source
Two new studies have given further weight to the benefits of delayed cord clamping, finding waiting for at least 2 minutes to clamp the umbilical cord of premature babies at birth could decrease the child's risk of death.
Published Cycle of fasting and feeding is crucial for healthy aging (via sciencedaily.com) Original source
Fasting interventions, which involve alternating periods of fasting and refeeding, are generally thought to improve health. But these interventions don't work as well in old animals. The question is: Why? By studying the short-lived killifish, researchers have shown that older fish deviate from a youthful fasting and refeeding cycle, and instead enter a state of perpetual fasting, even when ingesting food. However, the benefits of refeeding after fasting in old killifish can be restored by genetically activating a specific subunit of AMP kinase, an important sensor of cellular energy. These mutant fish experienced improved health and longevity, indicating that both fasting and refeeding are needed to confer health benefits and act through AMP kinase to do so.
Published New drug-like molecule extends lifespan, ameliorates pathology in worms and boosts function in mammalian muscle cells (via sciencedaily.com) Original source
Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process. Researchers have identified a new drug-like molecule that keeps mitochondria healthy via mitophagy, a process that removes and recycles damaged mitochondria in multicellular organisms. The compound, dubbed MIC, is a natural compound that extended lifespan in C. elegans, ameliorated pathology in neurodegenerative disease models of C. elegans, and improved mitochondrial function in mouse muscle cells.
Published Umbilical cord milking appears to be safe in preterm infants born after 28 weeks (via sciencedaily.com) Original source
A treatment to move blood from the umbilical cord into an infant's body may provide a safe option for preterm infants born after 28 weeks who need rapid support, suggests a new study. The procedure, called umbilical cord milking, involves gently squeezing the cord between the thumb and forefinger and pushing the blood into the newborn's abdomen. The new findings suggest that concerns raised by a 2019 study of infants born before 28 weeks -- which concluded that umbilical cord milking might increase the risk of bleeding inside the brain -- do not apply to preterm infants born after 28 weeks.
Published Zen and the art of mitochondrial maintenance: The machinery of death makes a healthier life (via sciencedaily.com) Original source
While we all aspire for a long lifespan, what is most coveted is a long period of vigor and health, or 'healthspan,' that precedes the inevitable decline of advancing age. Researchers have discovered that instruments of death that cells use to commit suicide when things go wrong contribute to making a longer and healthier life by revitalizing the specialized cellular compartments called mitochondria.
Published Artificial bladders shine light on bugs that cause urinary tract infections (via sciencedaily.com) Original source
A new study reveals that numerous bacterial strains are capable of hiding in the human bladder wall, suggesting why urinary tract infections often persist after treatment.