Showing 20 articles starting at article 1
Published Body's immune response may offer alternative approach to neuropathic pain therapies (via sciencedaily.com) Original source
In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe.
Published Follow the leader: Researchers identify mechanism of cancer invasion (via sciencedaily.com) Original source
A cancerous tumor is the accumulation of cells uncontrollably dividing, some of which can invade other parts of the body. The process is difficult to predict in detail, and eradicating the cells poses even greater difficulty. Now, a research team has revealed how the exodus initiates, shedding light on a potential therapeutic target to halt the invasion and providing a prognostic marker to help clinicians select the best treatment option.
Published Poor sense of smell linked to increased risk of depression in older adults (via sciencedaily.com) Original source
In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.
Published Pain not perceived in the same way in people with Alzheimer's Disease (via sciencedaily.com) Original source
New research has found that in a mouse model mimicking Alzheimer's Disease (AD) pain signals are not processed in the same way as in healthy mice.
Published Loss of Y chromosome in men enables cancer to grow (via sciencedaily.com) Original source
As men age, some of their cells lose the very thing that makes them biological males -- the Y chromosome -- and this loss hampers the body's ability to fight cancer, according to new research. The study found that loss of the Y chromosome helps cancer cells evade the body's immune system. This common impact of the aging process in men results in aggressive bladder cancer, but somehow also renders the disease more vulnerable -- and responsive -- to a standard treatment called immune checkpoint inhibitors.
Published New findings show mitochondrial DNA fragments in blood as important biomarkers for aging and inflammation (via sciencedaily.com) Original source
In an eight-year study of more than 600 community-dwelling older adults, researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty. The study is novel and expands on previous work, the investigators say, because it focused on mitochondrial DNA rather than solely genomic DNA, as previously reported.
Published Close up on aging reveals how different cell types in the body age at different pace (via sciencedaily.com) Original source
A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Published Pregnancy hormone repairs myelin damage in MS mouse model (via sciencedaily.com) Original source
A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
Published Ultra small molecule as a new target for Alzheimer's disease? (via sciencedaily.com) Original source
A new study shows that a very small molecule called microRNA-132 can have a significant impact on different brain cells and may play a role in Alzheimer's disease.
Published Altered gut bacteria may be early sign of Alzheimer's disease (via sciencedaily.com) Original source
Alzheimer's disease causes changes to the brain that begin two decades or more before symptoms appear. A study reveals that the bacteria that live in the gut also change before Alzheimer's symptoms arise, a discovery that could lead to diagnostics or treatments for Alzheimer's disease that target the gut microbiome.
Published Taurine may be a key to longer and healthier life (via sciencedaily.com) Original source
A study finds that deficiency of taurine, a molecule produced in our bodies, drives aging, and taurine supplements can improve health and increase lifespan in animals.
Published The IL-17 protein plays a key role in skin aging (via sciencedaily.com) Original source
A team of scientists has discovered that IL-17 protein plays a central role in skin aging. The study highlights an IL-17-mediated ageing process to an inflammatory state.
Published A chance observation finds potential hearing biomarker for Alzheimer's disease (via sciencedaily.com) Original source
Researchers found where plaques are found in the brain may impact hearing in Alzheimer's disease.
Published Sea cucumbers: The marine delicacy that can deter diabetes (via sciencedaily.com) Original source
They're a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research.
Published Poorly insulated nerve cells promote Alzheimer's disease in old age (via sciencedaily.com) Original source
Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
Published Why do some people live to be 100? Intestinal bacteria may hold the answer (via sciencedaily.com) Original source
Some people live longer than others -- possibly due to a unique combination of bacteria in their intestines, new research concludes.
Published Tracking early signs of Alzheimer's pathology in a mouse model (via sciencedaily.com) Original source
About two-thirds of the risk for Alzheimer's disease (AD) is thought to arise from genetic influences, but about a third could be influenced by environment and lifestyle, opening the door for behavioral interventions that could delay or prevent pathophysiological changes that occur with AD. Now a new study in a mouse model of AD examines the effects of environmental enrichment on AD symptom progression and pathology.
Published Eat right, live longer: Could a moderate protein diet be the coveted elixir of youth? (via sciencedaily.com) Original source
Consuming nutritious food can improve metabolic health and delay aging. But what are the appropriate quantities of dietary macronutrients that can help achieve this? To answer this, researchers fed isocaloric diets with varying amounts of protein to young and middle-aged male mice. They found that the mice were metabolically healthier when fed moderate-protein diets. These findings could provide valuable insights into developing nutritional interventions and improving metabolic health in people.
Published Low sexual satisfaction linked to memory decline later in life (via sciencedaily.com) Original source
Low sexual satisfaction in middle age may serve as an early warning sign for future cognitive decline, according to a new study. The study, which tracked associations between erectile function, sexual satisfaction and cognition in hundreds of men aged 56 through 68, found that declines in sexual satisfaction and erectile function were correlated with future memory loss.
Published Low-flavanol diet drives age-related memory loss, large study finds (via sciencedaily.com) Original source
Age-related memory loss is likely caused, in part, by lack of flavanols -- nutrients found in certain fruits and vegetables -- according to a large study in older adults.