Showing 20 articles starting at article 1
Published Stem cell-based treatment controls blood sugar in people with Type 1 diabetes (via sciencedaily.com) Original source
An innovative stem cell-based treatment for Type 1 diabetes can meaningfully regulate blood glucose levels and reduce dependence on daily insulin injections, according to new clinical trial results. The therapy aims to replace the insulin-producing beta cells that people with Type 1 diabetes lack. Dubbed VC-02, the small medical implant contains millions of lab-grown pancreatic islet cells, including beta cells, that originate from a line of pluripotent stem cells.
Published Novel molecular mechanisms in the early development of diabetes mellitus (via sciencedaily.com) Original source
Researchers conducted a gene expression analysis at the single-cell level on pancreatic islets from prediabetic and diabetic mouse models. Analysis results revealed upregulation of Anxa10 expression in pancreatic beta cells during the early phases of diabetes, attributed to elevated blood glucose levels. This elevated Anxa10 expression was found to influence intracellular calcium homeostasis, leading to a reduction in insulin secretory capacity.
Published Poor work performance among Japanese employees strongly associated with insufficient sleep (via sciencedaily.com) Original source
This study examined the association between work performance and lifestyle habits among Japanese employees. The results revealed that insufficient sleep was the predominant factor affecting work performance in men and women, followed by lack of regular exercise and eating late-evening meals. Furthermore, the study indicated that men were more likely to exhibit lifestyle habits that impacted work performance than women.
Published Feeding dogs raw meat increases the risk of antibiotic-resistant E. coli (via sciencedaily.com) Original source
Feeding dogs raw (uncooked) meat increases their risk of excreting E. coli that cannot be killed by a widely used antibiotic -- ciprofloxacin -- researchers have found from a study of 600 healthy pet dogs.
Published Following a Mediterranean diet reduces the risk of cognitive decline in older people (via sciencedaily.com) Original source
Old people who follow a Mediterranean diet are at a lower risk of cognitive decline, according to a new study. The study provides new evidence for a better understanding of the biological mechanisms related to the impact of the diet on cognitive health in the aging population.
Published Hormones have the potential to treat liver fibrosis (via sciencedaily.com) Original source
Researchers have discovered previously unknown changes in a specific type of liver cells, potentially opening avenues for a new treatment for liver fibrosis, a potentially life-threatening condition. Currently, there are no drugs available to treat liver fibrosis.
Published People with obesity burn less energy during day (via sciencedaily.com) Original source
A study found people who have a healthy weight use more energy during the day, when most people are active and eat, while those who have obesity spend more energy during the night, when most people sleep. Researchers also found that, during the day, those with obesity have higher levels of the hormone insulin -- a sign that the body is working harder to use glucose, an energy-packed sugar.
Published NHS Diabetes Prevention Programme may have global impact (via sciencedaily.com) Original source
As ten percent of the world's adult population is predicted to have diabetes by 2030, a major new study finds that the NHS Diabetes Prevention Programme has a positive effect on reducing risk of developing diabetes.
Published Peer educators play key role in new recipe development and testing (via sciencedaily.com) Original source
Cooking and recipe demonstrations encourage healthy eating and adoption of unfamiliar foods by class participants.
Published Semaglutide reduced cardiovascular events by 20% in certain adults (via sciencedaily.com) Original source
Semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes, according to new research. Semaglutide is primarily prescribed for adults with type 2 diabetes but is also approved for chronic weight management in adults with obesity or overweight and have at least one other health issue. In the trial, patients treated with semaglutide lost an average of 9.4% of their body weight and experienced improvements in other risk factors for cardiovascular disease. Results from the 'SELECT -- Semaglutide and Cardiovascular Outcomes in Patients with Overweight or Obesity Who Do Not Have Diabetes' trial were presented today during a late-breaking science session at the American Heart Association's Scientific Sessions 2023 and simultaneously published in the New England Journal of Medicine.
Published Shortening sleep time increases diabetes risk in women (via sciencedaily.com) Original source
A new study in women found that shortening sleep by just 90 minutes for a few weeks increased insulin resistance, a risk factor for type 2 diabetes.
Published Drug screen points toward novel diabetes treatments (via sciencedaily.com) Original source
A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study. The preclinical discovery provides a new chemical tool for probing the biology of diabetes, and could point the way toward better treatments for the disease.
Published Allergic responses to common foods could significantly increase risk of heart disease, cardiovascular death (via sciencedaily.com) Original source
Allergic responses to common foods such as dairy and peanuts can increase the risk for heart disease and cardiovascular death as much or more than smoking, new research suggests. And these dangerous allergic responses can strike both people with food allergies and those with no obvious allergy symptoms.
Published Obesity linked to neurodegeneration through insulin resistance (via sciencedaily.com) Original source
Researchers have discovered a link between obesity and neurodegenerative disorders like Alzheimer's disease. Using the common fruit fly, the research shows that a high-sugar diet -- a hallmark of obesity -- causes insulin resistance in the brain, which in turn reduces the ability to remove neuronal debris, thus increasing the risk of neurodegeneration.
Published A step closer to injection-free diabetes care: Innovation in insulin-producing cells (via sciencedaily.com) Original source
A team has developed a new step to improve the process for creating insulin-producing pancreatic cells from a patient's own stem cells, bringing the prospect of injection-free treatment closer for people with diabetes.
Published Practicing mindfulness can help people make heart-healthy eating choices (via sciencedaily.com) Original source
A study found that participants in a mindfulness-based blood pressure reduction program improved health behaviors that lower blood pressure. When people who had elevated blood pressure participated in an eight-week mindfulness-based blood pressure reduction program, they significantly improved their scores on measures of self-awareness and adherence to a heart-healthy diet compared to a control group.
Published Repurposed drug offers new potential for managing type 1 diabetes (via sciencedaily.com) Original source
A new study presents exciting future possibilities for the management of type 1 diabetes and the potential reduction of insulin dependency. The study's findings suggest repurposing of the drug alpha-difluoromethylornithine (DFMO) may open doors to innovative therapies in the future.
Published New research links high salt consumption to risk of Type 2 diabetes (via sciencedaily.com) Original source
The study surveyed more than 400,000 adults and found that participants who 'sometimes,' 'usually,' or 'always' added salt had a respective 13%, 20%, and 39% higher risk of developing Type 2 diabetes.
Published High insulin levels directly linked to pancreatic cancer (via sciencedaily.com) Original source
The first detailed explanation of why people with obesity and Type 2 diabetes are at an increased risk of pancreatic cancer has been published. The research demonstrates that excessive insulin levels overstimulate pancreatic acinar cells, which produce digestive juices. This overstimulation leads to inflammation that converts these cells into precancerous cells. The researchers say the findings may have implications for other cancers associated with obesity and Type 2 diabetes, where elevated insulin levels may also play a contributing role in disease initiation.
Published Weekly insulin injections have the potential to be as effective in diabetes management as now-common daily injection regimes (via sciencedaily.com) Original source
Insulin icodec, a once-weekly basal injection to treat type 1 diabetes, has the potential to be as effective in managing the condition as daily basal insulin treatments, according to new research. The results of the year-long phase 3 clinical trial could revolutionize the future of diabetes care and help millions of people better manage their condition.