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Categories: Diabetes, Neuropathy

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Neuropathy
Published

Body's immune response may offer alternative approach to neuropathic pain therapies      (via sciencedaily.com)     Original source 

In the midst of a global opioid epidemic, a team of scientists is exploring natural killer (NK) cells as an alternative treatment for neuropathic pain. Researchers gather existing evidence for the impact of NK cells in pain, pointing to their ability to prune the damaged nerve cells that may cause it. They urge the scientific community to explore biological mechanisms underlying NK cell activity to move towards a realistic pain therapy that is both effective and safe.

Diabetes
Published

Hidden mechanism connects cancer and diabetes      (via sciencedaily.com)     Original source 

Insulin resistance is usually associated with type 2 diabetes. Now researchers have found it in cancer patients and learned that it can cause cancer to spread faster.

Neuropathy Pregnancy and Childbirth Psychology Research
Published

Pregnancy hormone repairs myelin damage in MS mouse model      (via sciencedaily.com)     Original source 

A new study has identified a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.

Diabetes Diet and Weight Loss Nutrition Obesity
Published

Fewer meals may prevent Type 2 diabetes, obesity      (via sciencedaily.com)     Original source 

When intermittent fasting became all the rage among Hollywood celebrities, skeptics balked at the idea of skipping meals. But new research suggests the celebs might not have been that far off. The review found that a specific type of restricted eating may reduce the chances of developing Type 2 diabetes and improve your overall health. Known as time-restricted eating, this type of fasting means having regular but fewer meals, cutting out late-night snacks and not eating for 12 to 14 hours (often overnight).

Children's Health Diabetes Today's Healthcare
Published

Machine-learning method used for self-driving cars could improve lives of type-1 diabetes patients      (via sciencedaily.com)     Original source 

The same type of machine learning methods used to pilot self-driving cars and beat top chess players could help type-1 diabetes sufferers keep their blood glucose levels in a safe range.

Chronic Illness Diabetes Healthy Aging
Published

Sea cucumbers: The marine delicacy that can deter diabetes      (via sciencedaily.com)     Original source 

They're a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research.

Diabetes
Published

Can exercise help counteract genetic risk of disease?      (via sciencedaily.com)     Original source 

Staying active could help keep the onset of type 2 diabetes at bay, even if someone has a genetic risk of developing the disease. Researchers say this highlights the importance of exercise in chronic disease prevention.

Diabetes
Published

Scientists target human stomach cells for diabetes therapy      (via sciencedaily.com)     Original source 

Stem cells from the human stomach can be converted into cells that secrete insulin in response to rising blood sugar levels, offering a promising approach to treating diabetes, according to a preclinical study.

Diabetes
Published

Experimental drug inhibits or prevents diabetic eye disease      (via sciencedaily.com)     Original source 

Researchers say they have evidence that an experimental drug may prevent or slow vision loss in people with diabetes. The results are from a study that used mouse as well as human retinal organoids and eye cell lines.

Diabetes Today's Healthcare
Published

Afternoon exercise linked with greater improvements in blood sugar levels for patients with type 2 diabetes      (via sciencedaily.com)     Original source 

A new study uses data from the Look AHEAD (Action for Health in Diabetes) study, a randomized controlled trial that compared an intensive lifestyle intervention with diabetes support and education in patients diagnosed with type 2 diabetes and overweight or obesity to track the development of cardiovascular disease over time.

Diabetes
Published

Researchers map the brain during blood sugar changes      (via sciencedaily.com)     Original source 

Researchers have successfully mapped specific regions in the brain that are activated in association with changes in blood sugar -- also known as glucose -- providing fundamental location information that could ultimately lead to more targeted therapies for people who struggle with conditions like diabetes.

Neuropathy
Published

New chemical compound demonstrates potential in nerve regeneration      (via sciencedaily.com)     Original source 

Recent research has identified a new compound that can stimulate nerve regeneration after injury, as well as protect cardiac tissue from the sort of damage seen in heart attack.

Diabetes
Published

Artificial pancreas reduces disease management burden for people with diabetes      (via sciencedaily.com)     Original source 

Researchers design a novel algorithm for controlling implanted insulin pumps that accounts for the unique characteristics of individual patients. Their model, tested using an FDA-approved diabetes computer simulation, proves intraperitoneal (within the abdominal cavity) insulin delivery is fast and closely mimics natural physiological insulin delivery. They developed a model that can account for individual patient differences and validated a pump control algorithm that does not require meal announcement.

Neuropathy
Published

Neuropathic pain: The underlying mechanism and a potential therapeutic target are revealed in mice      (via sciencedaily.com)     Original source 

Neuropathic pain -- abnormal hypersensitivity to stimuli -- is associated with impaired quality of life and is often poorly managed. Estimates suggest that 3 percent to 17 percent of adults suffer from neuropathic pain, including a quarter of people with diabetes and a third of people with HIV. Researchers report that a mechanism involving the enzyme Tiam1 in dorsal horn excitatory neurons of the spinal cord both initiates and maintains neuropathic pain. Moreover, they show that targeting spinal Tiam1 with anti-sense oligonucleotides injected into the cerebrospinal fluid effectively alleviated neuropathic pain hypersensitivity.

Diabetes
Published

High-throughput experiments might ensure a better diagnosis of hereditary diseases      (via sciencedaily.com)     Original source 

All human beings are genetically very similar, sharing approx. 99.9% of the DNA code. The remaining 0.1% explains the natural differences between people, including our predisposition to hereditary diseases. Although sequencing of our genetic material is becoming a routine diagnostic analysis, it is unfortunately far from simple to determine whether specific small differences in our DNA affect our risk of developing disease. The usefulness of DNA sequencing is therefore often limited to the few cases where it is already known if a gene variant increases the risk of disease.

Diabetes
Published

Potential breakthrough in Type 1 diabetes treatment      (via sciencedaily.com)     Original source 

Scientists identified three biomaterial formulations that could help develop a more sustainable, long-term, self-regulating way to treat Type 1 diabetes using a new screening technique that involves tagging each biomaterial formulation in a library of hundreds with a unique 'barcode.'

Birth Defects Chronic Illness Neuropathy
Published

How alcohol consumption contributes to chronic pain      (via sciencedaily.com)     Original source 

A team showed how both alcohol intake and alcohol withdrawal can lead to increased pain and hypersensitivity.

Diabetes
Published

Too much insulin can be as dangerous as too little      (via sciencedaily.com)     Original source 

Researchers describe a key player in the defense mechanism that safeguards against excessive insulin in the body, which can be as harmful as too little.

Diabetes Skin Care Today's Healthcare
Published

How electricity can heal wounds three times as fast      (via sciencedaily.com)     Original source 

Chronic wounds are a major health problem for diabetic patients and the elderly -- in extreme cases they can even lead to amputation. Using electric stimulation, researchers have developed a method that speeds up the healing process, making wounds heal three times faster.