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Categories: Diabetes, Hormone Disorders

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Diabetes Diet and Weight Loss
Published

This outdated diabetes drug still has something to offer      (via sciencedaily.com)     Original source 

Researchers have discovered the biochemical workings of an old-fashioned diabetes drug, and it's helping them develop new, safer alternatives.

Diabetes Fitness
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Does the time of day you move your body make a difference to your health?      (via sciencedaily.com)     Original source 

Undertaking the majority of daily physical activity in the evening is linked to the greatest health benefits for people living with obesity, according to researchers who followed the trajectory of 30,000 people over almost 8 years.

Diabetes
Published

Beating back bitter taste in medicine      (via sciencedaily.com)     Original source 

The bitter taste of certain drugs is a barrier to taking some medications as prescribed, especially for people who are particularly sensitive to bitter taste. A team found that the diabetes drug rosiglitazone could partially block the bitter taste of some especially bad-tasting medications. The hope is that repurposed drugs could be added in small doses to other medicines to make them less bitter and taste better, thereby encouraging compliance with bitter drug regimens.

Diabetes Diet and Weight Loss Obesity Today's Healthcare
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Few newly diagnosed type 2 diabetics succeed in losing weight -- weight gain linked to much higher risk of complications      (via sciencedaily.com)     Original source 

A register-based study identified three distinct BMI trajectory groups among patients with newly diagnosed type 2 diabetes. In a four-year follow-up, most patients followed a stable trajectory without much weight change. Only 10% of patients lost weight, whereas 3% gained weight. Mean BMI exceeded the threshold of obesity in all groups at baseline. Weight loss is a central treatment goal in type 2 diabetes, but the study shows that few patients succeed in it.

Diabetes Today's Healthcare
Published

Study finds less invasive, safer option for removing benign pancreatic tumors      (via sciencedaily.com)     Original source 

Researchers describe a new technique for the minimally invasive removal of benign tumors located in the challenging posterior head of the pancreas (right side of abdomen, nestled in the curve of the duodenum (or first part of the small intestine). The technique, called the retro-laparoscopic approach, allows surgeons to safely and effectively remove these tumors without removing healthy pancreatic tissue, thereby preserving organ functionality.

Child Development Diabetes
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Large language models respond differently based on user's motivation      (via sciencedaily.com)     Original source 

A new study reveals how large language models (LLMs) respond to different motivational states. In their evaluation of three LLM-based generative conversational agents (GAs)--ChatGPT, Google Bard, and Llama 2, scientists found that while GAs are able to identify users' motivation states and provide relevant information when individuals have established goals, they are less likely to provide guidance when the users are hesitant or ambivalent about changing their behavior.

Diabetes Skin Care Today's Healthcare
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Wound treatment gel fights the battle against antibacterial resistance      (via sciencedaily.com)     Original source 

Polymer-based hydrogels are used to treat skin ailments and in tissue engineering because of their ability to retain water, deliver drugs into wounds, and biodegrade. However, they are complicated to manufacture and not very resilient to external forces like rubbing against clothing, sheets, or wound dressings. Scientists have now created a hydrogel enhanced with the amino acid polylysine and blood plasma that is easier to synthesize, contains natural antibiotic properties, and promotes cell growth.

Diabetes Diet and Weight Loss Nutrition Obesity
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Do sweeteners increase your appetite? New evidence from randomised controlled trial says no      (via sciencedaily.com)     Original source 

Replacing sugar with artificial and natural sweeteners in foods does not make people hungrier -- and also helps to reduce blood sugar levels, a significant new study has found. The double blind randomized controlled trial found that consuming food containing sweeteners produced a similar reduction in appetite sensations and appetite-related hormone responses as sugary foods -- and provides some benefits such as lowering blood sugar, which may be particularly important in people at risk of developing type 2 diabetes. The use of sweeteners in place of sugar in foods can be controversial due to conflicting reports about their potential to increase appetite. Previous studies have been carried out but did not provide robust evidence. However, the researchers say their study, which meets the gold standard level of proof in scientific investigation, provides very strong evidence that sweeteners and sweetness enhancers do not negatively impact appetite and are beneficial for reducing sugar intake.

Chronic Illness Depression Diabetes Mental Health Research Psychology Research
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For younger women, mental health now may predict heart health later      (via sciencedaily.com)     Original source 

Younger women are generally thought to have a low risk of heart disease, but new research urges clinicians to revisit that assumption, especially for women who suffer from certain mental health conditions. A new study found that having anxiety or depression could accelerate the development of cardiovascular risk factors among young and middle-aged women.

Diabetes Diet and Weight Loss Dietary Supplements and Minerals Nutrition Vitamin
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Eggs may not be bad for your heart after all      (via sciencedaily.com)     Original source 

Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a prospective, controlled trial show that over a four-month period cholesterol levels were similar among people who ate fortified eggs most days of the week compared with those who didn't eat eggs.

Birth Control Diabetes Pregnancy and Childbirth Today's Healthcare
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Miscarriages linked to health risks in later pregnancies      (via sciencedaily.com)     Original source 

Researchers analyzed 52 studies involving more than 4 million pregnancies across 22 countries to investigate the health impacts of miscarriage, abortion and recurrent pregnancy loss (more than two miscarriages in succession) on subsequent pregnancies. The study found different health risks for each group.

Chronic Illness Diabetes
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Clear shift in arterial diseases in diabetes      (via sciencedaily.com)     Original source 

There has been a redistribution in the risk of arterial disease in type 1 and 2 diabetes. The risks of heart attack and stroke have decreased significantly, while complications in more peripheral vessels have increased in relative importance, according to new studies.

Diabetes Diet and Weight Loss Dieting and Weight Control Healthy Aging Psychology Research
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Risk factors for faster aging in the brain revealed in new study      (via sciencedaily.com)     Original source 

Researchers have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.

Diabetes Neuropathy Skin Care Today's Healthcare
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Discovery has potential to solve the billion-dollar global cost of poorly managed wound healing      (via sciencedaily.com)     Original source 

Scientists have uncovered a key step in the wound healing process that becomes disabled in diseases like diabetes and aging, contributing to a global healthcare cost of managing poorly healing wounds exceeding $250 billion a year. Importantly, the research reveals a molecule involved in the healing of tissues that -- when injected into animal models -- leads to a drastic acceleration of wound closure, up to 2.5 times faster, and 1.6 times more muscle regeneration.

Diabetes Diet and Weight Loss Dieting and Weight Control Nutrition Obesity Parenting Pregnancy and Childbirth Psychology Research
Published

Metformin during pregnancy affects the brain development in offspring mice, study finds      (via sciencedaily.com)     Original source 

With the rise in gestational diabetes and metabolic disorders during pregnancy, metformin is also being prescribed more frequently. Although it is known that the oral antidiabetic agent can cross the placental barrier, the impacts on the brain development of the child are largely unknown. Researchers have now been able to demonstrate in a mouse model that although metformin has positive effects in pregnant animals, it does not in the offspring.

Diabetes
Published

Insulin affects the recycling of cellular power plants      (via sciencedaily.com)     Original source 

In nerve cells, the hormone regulates whether mitochondria are shut down or kept running.

Diabetes Diet and Weight Loss Fitness Obesity
Published

Kallistatin contributes to the beneficial metabolic effects of weight loss      (via sciencedaily.com)     Original source 

After weight loss, people with overweight and obesity express more of the protein Kallistatin in subcutaneous white adipose tissue. Kallistatin improves metabolism and could open up new therapeutic options for people with obesity and type 2 diabetes in future.

Diabetes
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Study with innovative insights into the heterogeneity of type 2 diabetes      (via sciencedaily.com)     Original source 

A landmark study sheds new light on the heterogeneity of type 2 diabetes. The researchers employed an innovative algorithm to stratify people with type 2 diabetes using routine data and thus visualize the metabolic diversity of diabetes.

Chronic Illness Diabetes
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Potential novel biomarkers of coronary heart disease discovered      (via sciencedaily.com)     Original source 

Coronary heart disease is a major global health problem, especially among people with type 2 diabetes. Researchers have identified novel protein biomarkers that are associated with the development of CHD in people with and without diabetes.

Diabetes Today's Healthcare
Published

Revolutionary chronic wound treatment could help millions      (via sciencedaily.com)     Original source 

An effective treatment for chronic wounds that does not involve antibiotics, but an ionised gas to activate a wound dressing, has been developed by a team of international scientists.