Showing 20 articles starting at article 1
Categories: Depression, Neuropathy
Published Lost brain function restored in mice after stroke
(via sciencedaily.com) Original source Researchers have succeeded in restoring lost brain function in mouse models of stroke using small molecules that in the future could potentially be developed into a stroke recovery therapy.
Published Common headaches tied to neck inflammation
(via sciencedaily.com) Original source Researchers have identified objective evidence of how the neck muscles are involved in primary headaches, according to a new study.
Published Heart over head? Stages of the heart's cycle affect neural responses
(via sciencedaily.com) Original source Optimal windows exist for action and perception during the 0.8 seconds of a heartbeat, according to new research. The sequence of contraction and relaxation is linked to changes in the motor system and its ability to respond to stimulation, and this could have implications for treatments for depression and stroke that excite nerve cells.
Published Fat cells help repair damaged nerves
(via sciencedaily.com) Original source Damage to the body's peripheral nerves can cause pain and movement disorders. Researchers have recently investigated how damaged nerves can regenerate better. They found that fat tissue strongly supports the Schwann cells needed for repair during the healing process.
Published Understanding subjective beliefs could be vital to tailoring more effective treatments for depression and ADHD
(via sciencedaily.com) Original source Taking into account whether people believe they are receiving a real treatment or a fake one (placebo) could provide better insights that could help improve interventions for conditions such as depression and ADHD.
Published Repairing nerve cells after injury and in chronic disease
(via sciencedaily.com) Original source Researchers discovered a mechanism for repairing damaged nerves during peripheral neuropathy in mice, wherein the protein Mitf orchestrates nerve repair after both trauma-induced and chronic nerve damage conditions, like Charcot Marie Tooth disease. Their findings may inspire novel therapeutics that bolster repair function and heal peripheral neuropathy -- even in hereditary and developmental cases.
Published Discrimination during pregnancy can affect infant's brain circuitry
(via sciencedaily.com) Original source Experiences of discrimination and acculturation are known to have a detrimental effect on a person's health. For pregnant women, these painful experiences can also affect the brain circuitry of their children, a new study finds. These effects, the researchers say, are separate from those caused by general stress and depression. The study was published in the journal Neuropsychopharmacology.
Published Getting to the root of visceral gut pain
(via sciencedaily.com) Original source Researchers have uncovered a reason that may explain why visceral pain is so common in conditions like irritable bowel syndrome. This understanding could inspire new and better ways to alleviate that pain.
Published A small molecule blocks aversive memory formation, providing a potential treatment target for depression
(via sciencedaily.com) Original source Depression is one of the most common mental illnesses in the world, but current anti-depressants have yet to meet the needs of many patients. Neuroscientists recently discovered a small molecule that can effectively alleviate stress-induced depressive symptoms in mice by preventing aversive memory formation with a lower dosage, offering a new direction for developing anti-depressants in the future.
Published High levels of maternal stress during pregnancy linked to children's behavior problems
(via sciencedaily.com) Original source Children whose mothers are highly stressed, anxious or depressed during pregnancy may be at higher risk for mental health and behavior issues during their childhood and teen years, according to new research.
Published New studies of brain activity explain benefits of electroconvulsive therapy
(via sciencedaily.com) Original source Researchers have shed new light on why electroconvulsive therapy has such a high success rate, a mystery that has puzzled doctors and scientists for almost a century. Findings could help improve this controversial treatment.
Published Genetic testing could greatly benefit patients with depression, save health system millions
(via sciencedaily.com) Original source A special kind of genetic test that helps determine the best antidepressant for patients with moderate-to-severe depression could generate substantive health system savings and greatly improve patient outcomes, according to new research. The study shows that in B.C. alone, implementing pharmacogenomic testing could save the provincial public health system an estimated $956 million over 20 years.
Published New compound outperforms pain drug by indirectly targeting calcium channels
(via sciencedaily.com) Original source A compound -- one of 27 million screened in a library of potential new drugs -- reversed four types of chronic pain in animal studies, according to new research. The small molecule, which binds to an inner region of a calcium channel to indirectly regulate it, outperformed gabapentin without troublesome side effects, providing a promising candidate for treating pain.
Published Brain imaging identifies biomarkers of mental illness
(via sciencedaily.com) Original source Research and treatment of psychiatric disorders are stymied by a lack of biomarkers -- objective biological or physiological markers that can help diagnose, track, predict, and treat diseases. In a new study, researchers use a very large dataset to identify predictive brain imaging-based biomarkers of mental illness in adolescents.
Published Disturbances in sensory neurons may alter transient pain into chronic pain
(via sciencedaily.com) Original source Researchers have identified that a transient inflammatory pain causes mitochondrial and redox changes in sensory neurons that persist beyond pain resolution. These changes appear to predispose to a failure in resolution of pain caused by a subsequent inflammation. Additionally, targeting the cellular redox balance prevents and treats chronic inflammatory pain in rodents.
Published Poetry can help people cope with loneliness or isolation
(via sciencedaily.com) Original source Research has found that many people who took to sharing, discussing and writing poetry as a means to deal with the COVID-19 pandemic experienced 'demonstrable positive impact on their wellbeing'.
Published When dads are feeling a bit depressed or anxious, how do kids fare?
(via sciencedaily.com) Original source A team of researchers has found that slightly higher, but mild anxious or depressive symptoms in fathers were associated with fewer behavioral difficulties in the first years of elementary school and better scores on a standardized IQ test in their children.
Published Location of strong sense of discomfort in brain found
(via sciencedaily.com) Original source Researchers have identified a new neural circuit in the brain which produces a strong sense of discomfort when activated. The discovery also allows them to show for the first time that the subthalamic nucleus, a structure in the brain that controls voluntary movements, may also play a role in the development of depression. The results could lead to better treatments for Parkinson's disease.
Published Paid family leave boosted postpartum wellbeing, breastfeeding rates
(via sciencedaily.com) Original source A new study has found postpartum individuals living in states with generous mandated paid family and medical leave (PFML) are more likely to breastfeed and less likely to experience postpartum depression symptoms compared to those living in states with little or no mandated state-paid leave. The findings were even more pronounced among lower-income populations covered by Medicaid.
Published New clues to the mechanism behind treatment-resistant depression
(via sciencedaily.com) Original source Major depressive disorder (MDD) is a widespread mental health condition that for many is disabling. It has long been appreciated that MDD has genetic as well as environmental influences. In a new study researchers identify a gene that interacted with stress to mediate aspects of treatment-resistant MDD in an animal model.